ANTI-MDM2
- CAS No.
- Chemical Name:
- ANTI-MDM2
- Synonyms
- MDMX;HDMX;HDM2;MGC5370;MGC71221;Anti-HDM4;ANTI-MDM4;ANTI-MDM2;ANTI-HDMX;Anti-hdm2
- CBNumber:
- CB0241012
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00282354
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P305+P351+P338 |
| WGK Germany | 3 |
ANTI-MDM2 price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB4503937 | Anti-phospho-MDM2 (pSer166) antibody produced in rabbit affinity isolated antibody | 100μg | $506 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB4501852 | Anti-MDM4 antibody produced in rabbit affinity isolated antibody | 100μg | $506 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB4501849 | Anti-MDM2 antibody produced in rabbit affinity isolated antibody | 100μG | $506 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB4300601 | Anti-MDM2 (Ab-166) antibody produced in rabbit affinity isolated antibody | 100μg | $441 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB4300284 | Anti-phospho-MDM2 (pSer166) antibody produced in rabbit affinity isolated antibody | 100μg | $511 | 2024-03-01 | Buy |
ANTI-MDM2 Chemical Properties,Uses,Production
Uses
Monoclonal Anti-MDMX antibody is suitable for use in immunocytochemistry, immunoprecipitation, immunoblot (approx. 80 kDa), microarray, and ELISA. The product may also be used for western blot and for assessing ectopic expression of MDMX (using a conc. of 1-2 μg/mL in total cell extract of HEK 293T cells transfected with human MDMX).
General Description
Monoclonal Anti-MDMDX (mouse IgG1 isotype) is derived from the hybridoma MDMX-82 produced by the fusion of mouse myeloma cells (NS1 cells) and splenocytes from BALB/c mice. MDMX belongs to the MDM family. The MDMX/ mouse double minute 4 (MDM4) gene encode a 490 amino acid protein. MDMX comprises a putative nuclear localization signal, a really interesting new gene (RING) finger domain in the C terminal and a p53-binding domain in the N terminal. MDMX has significant structural similarity to MDM2 E3 ubiquitin ligase.
Biochem/physiol Actions
MDMX is a structural homolog of MDM2 and inhibits the tumor suppressor, p53. MDMX also prevents MDM2-mediated degradation of p53, and subsequently regulates cellular levels of p53. MDMX also modulates cell growth and survival. Thus, MDMX can be useful as a therapeutic target in cancers, especially in tumors where native p53 functions can be restored . Monoclonal Anti-MDMX antibody is specific for human MDMX.
ANTI-MDM2 Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-MDM2 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15839 | 69 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51456 | 80 |
| Shanghai guandao biology engineering co., ltd | 18818239863 18818239863 | 3171921642@qq.com | China | 8889 | 58 |
| Shanghai Huzhen Industrial Co., LTD | 021-60345367 13916550749 | sales@shzbio.com | China | 9966 | 58 |