ANTI-MDM2

ANTI-MDM2 Struktur
CAS-Nr.
Englisch Name:
ANTI-MDM2
Synonyma:
MDMX;HDMX;HDM2;MGC5370;MGC71221;Anti-HDM4;ANTI-MDM4;ANTI-MDM2;ANTI-HDMX;Anti-hdm2
CBNumber:
CB0241012
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

ANTI-MDM2 Eigenschaften

storage temp. 
−20°C
Aggregatzustand
buffered aqueous solution
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
WGK Germany  3
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
Sicherheit
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

ANTI-MDM2 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Monoclonal Anti-MDMX antibody is suitable for use in immunocytochemistry, immunoprecipitation, immunoblot (approx. 80 kDa), microarray, and ELISA. The product may also be used for western blot and for assessing ectopic expression of MDMX (using a conc. of 1-2 μg/mL in total cell extract of HEK 293T cells transfected with human MDMX).

Allgemeine Beschreibung

Monoclonal Anti-MDMDX (mouse IgG1 isotype) is derived from the hybridoma MDMX-82 produced by the fusion of mouse myeloma cells (NS1 cells) and splenocytes from BALB/c mice. MDMX belongs to the MDM family. The MDMX/ mouse double minute 4 (MDM4) gene encode a 490 amino acid protein. MDMX comprises a putative nuclear localization signal, a really interesting new gene (RING) finger domain in the C terminal and a p53-binding domain in the N terminal. MDMX has significant structural similarity to MDM2 E3 ubiquitin ligase.

Biochem/physiol Actions

MDMX is a structural homolog of MDM2 and inhibits the tumor suppressor, p53. MDMX also prevents MDM2-mediated degradation of p53, and subsequently regulates cellular levels of p53. MDMX also modulates cell growth and survival. Thus, MDMX can be useful as a therapeutic target in cancers, especially in tumors where native p53 functions can be restored . Monoclonal Anti-MDMX antibody is specific for human MDMX.

ANTI-MDM2 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ANTI-MDM2 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 30)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
3bsc@sina.com China 15839 69
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51456 80
Shanghai guandao biology engineering co., ltd 18818239863 18818239863
3171921642@qq.com China 8889 58
Shanghai Huzhen Industrial Co., LTD 021-60345367 13916550749
sales@shzbio.com China 9966 58

  • ANTI-UBIQUITIN PROTEIN LIGASE
  • ANTI-UBIQUITIN PROTEIN LIGASE (AB-1), HUMAN
  • p53-binding protein Mdm2
  • Ubiquitin-protein ligase E3 Mdm2
  • double minute 4 protein
  • Mdm2-like p53-binding protein
  • MDMX
  • p53-binding protein Mdm4
  • Anti-Double minute 4 protein
  • Anti-Mdm2-like p53-binding protein
  • Anti-MDM4 antibody produced in rabbit
  • Anti-p53-binding protein Mdm4
  • Anti-Protein Mdm4
  • Anti-Protein Mdmx
  • Anti-HGNC:6973
  • Anti-MDM2 (Isoform) antibody produced in goat
  • Anti-Transformed 3T3 cell double minute 2
  • Anti-MDM2 (Ab-166) antibody produced in rabbit
  • Anti-hdm2 antibody produced in rabbit
  • Anti-HDMX antibody produced in rabbit
  • Anti-Mdm2 p53 binding protein homolog (mouse) antibody produced in rabbit
  • Anti-MGC71221 antibody produced in rabbit
  • Anti-phospho-MDM2 (pSer166) antibody produced in rabbit
  • Anti-Mdm4, transformed 3T3 cell double minute 4, p53 binding protein (mouse)
  • HDMX
  • MDM2, untagged human
  • MGC5370
  • MGC71221
  • Anti-MDM2 antibody produced in chicken
  • Anti-Mouse double minute 2 homolog isoform MDM2
  • Anti-Ubiquitin-protein ligase E3 Mdm2
  • Anti-MDM2, C-Terminal antibody produced in rabbit
  • Anti-HDM4
  • Anti-MGC132766
  • ANTI-UBIQUITIN PROTEIN LIGASE (AB-1) MOUSE MAB
  • ANTI-UBIQUITIN PROTEIN LIGASE (AB-2), HUMAN
  • ANTI-UBIQUITIN PROTEIN LIGASE (AB-2) MOUSE MAB
  • ANTI-MDM4
  • ANTI-MDM2(C-18)
  • ANTI-MDM2(N-20)
  • ANTI-MDM2 PROTEIN
  • ANTI-MDM2
  • ANTI-MDM2 (AB-1)
  • ANTI-MDM2 (AB-1), HUMAN
  • ANTI-MDM2 (AB-1) MOUSE MAB
  • ANTI-MDM2 (AB-2)
  • ANTI-MDM2 (AB-2), HUMAN
  • ANTI-MDM2 (AB-2) MOUSE MAB
  • ANTI-MURINE DOUBLE MINUTE 2
  • ANTI-MURINE DOUBLE MINUTE CHROMOSOME-2 (AB-1) MOUSE MAB
  • ANTI-MURINE DOUBLE MINUTE CHROMOSOME 2 (AB-2)
  • ANTI-P53 BINDING PROTEIN
  • ANTI-P53 BINDING PROTEIN (AB-1), HUMAN
  • ANTI-P53 BINDING PROTEIN (AB-1) MOUSE MAB
  • ANTI-P53 BINDING PROTEIN (AB-2), HUMAN
  • ANTI-P53 BINDING PROTEIN (AB-2) MOUSE MAB
  • ANTI-ONCOPROTEIN MDM-2
  • ANTI-ONCOPROTEIN MDM-2, MOUSE
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