TH
- CAS No.
- Chemical Name:
- TH
- Synonyms
- TH;Anti-TYH;TYROSINE HYDROXYLASE;Human TH Protein, His Tag;Anti-th antibody produced in rabbit;Anti-TH (C-terminal) antibody produced in goat
- CBNumber:
- CB0244316
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00213057
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H317-H412 |
Precautionary statements | P261-P272-P273-P280-P302+P352-P333+P313 |
TH price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | SAB2701683 | Anti-th antibody produced in rabbit affinity isolated antibody, buffered aqueous solution | 100μL | $467 | 2024-03-01 | Buy | |
Sigma-Aldrich | HPA061003 | Anti-TH antibody produced in rabbit affinity isolated antibody, buffered aqueous glycerol solution | 25μL | $294 | 2024-03-01 | Buy | |
Sigma-Aldrich | SAB2501155 | Anti-TH (C-terminal) antibody produced in goat affinity isolated antibody, buffered aqueous solution | 100μg | $568 | 2024-03-01 | Buy | |
Sigma-Aldrich | HPA061003 | Anti-TH antibody produced in rabbit affinity isolated antibody, buffered aqueous glycerol solution | 100μL | $514 | 2024-03-01 | Buy | |
Usbiological | 028723 | Tyrosine Hydroxylase | 96Tests | $837 | 2021-12-16 | Buy |
TH Chemical Properties,Uses,Production
Description
An enzyme that is located in catecholamine-synthesizing cells and is responsible for the hydroxylation of L-tyrosine to L 3,4-dihydroxyphenylalanine (L-dopa). This is the initial and rate-limiting step in the biosynthetic pathway for catecholamines (dopamine, norepinephrine, and epinephrine). In addition to hydroxylating tyrosine using biopterin as a coenzyme, this enzyme can also hydroxylate phenylalanine to tyrosine. The enzyme is located in the cytosol of catecholamine neurons and has a Km for tyrosine that is in the micromolar range.
Uses
Anti-th antibody produced in rabbit has been used in:
- western blotting (1:1000)
- whole retinal flat-mount immunolabelling (1:500)
- immunofluorescence (2:1000)
- immunohistochemistry (2:1000)
General Description
Tyrosine hydroxylase?(TH) is a cytoplasmic enzyme. The TH gene codes for a monooxygenase.
Biochem/physiol Actions
Cell surface-associated protein is implicated in virulence. Promotes bacterial attachment exclusively to the γ-chain of human fibrinogen. Induces formation of bacterial clumps, which diminish the ability of group IIA phospholipase A2 to cause bacterial phospholipid hydrolysis and killing. Significantly decreases macrophage phagocytosis possibly thanks to the clumps, clumped bacteria being too large to be phagocytosed. Dominant factor responsible for human platelet aggregation, which may be an important mechanism for initiating infective endocarditis. Enhances spleen cell proliferative response in vitro, contributing significantly to the immunostimulatory activity of S.aureus.
TH Preparation Products And Raw materials
Raw materials
Preparation Products
TH Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Ontores Biotech | 0571-88760729 18072970094 | supports@ontorespeptide.com | China | 2696 | 58 |
Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10024 | 58 |
Shanghai Universal Biotech Co.,Ltd | 18768175414 | gaojun@univ-bio.com | China | 24998 | 58 |
Shanghai Yaji Biological Technology Co., Ltd. | 021-34661275 15301693058 | yajikit@163.com | China | 8373 | 58 |
Guangzhou Weihua Biotechnology Co., Ltd | 020-020-37239396 18922492046 | weihuasw@foxmail.com | China | 2074 | 58 |
Shanghai Huzhen Industrial Co., LTD | 021-60345367 13916550749 | sales@shzbio.com | China | 9965 | 58 |
Shanghai Yiyan Biotechnology Co. , Ltd. | 021-69985186 13611928337 | 3427709316@qq.com | China | 7984 | 58 |