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BROMAMPHENICOL

CAS No.
16803-75-1
Chemical Name:
BROMAMPHENICOL
Synonyms
Acetamide, 2,2-dibromo-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-
CBNumber:
CB02451280
Molecular Formula:
C11H12Br2N2O5
Molecular Weight:
412.03
MDL Number:
MFCD09837762
MOL File:
16803-75-1.mol

BROMAMPHENICOL Properties

Melting point 155-156 °C
Boiling point 664.4±55.0 °C(Predicted)
Density 1.939±0.06 g/cm3(Predicted)
pka 11.14±0.46(Predicted)

BROMAMPHENICOL price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B679578 Bromamphenicol 16803-75-1 10mg $120 2021-12-16 Buy
Product number Packaging Price Buy
B679578 10mg $120 Buy

BROMAMPHENICOL Chemical Properties,Uses,Production

Uses

Bromamphenicol is a semi-synthetic chloramphenicol analogue first reported in 1950, in which the dichloroacetamide is replaced with dibromoacetamide. Bromamphenicol possesses weak antibiotic activity. Comparative crystallography with chloramphenicol helped defined the SARs of the acetamide binding region on the ribosome. More recently, this relationship was used to demonstrate that chloramphenicol binding to DraE virulence factors in Gram negative bacteria was independent of chloramphenicol binding site on the ribosome.

Uses

Bromamphenicol is a semi-synthetic chloramphenicol analogue in which the dichloroacetamide is replaced with dibromoacetamide, first reported in 1950. Bromamphenicol possesses weak antibiotic activity. Comparative crystallography with chloramphenicol helped defined the SARs of the acetamide binding region on the ribosome. More recently, this relationship was used to demonstrate that chloramphenicol binding to DraE virulence factors in Gram negative bacteria was independent of chloramphenicol binding site on the ribosome.

BROMAMPHENICOL Preparation Products And Raw materials

Raw materials

Preparation Products

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Acetamide, 2,2-dibromo-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]- 16803-75-1 C11H12Br2N2O5