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Δ2-Cefepime

CAS No.
88040-25-9
Chemical Name:
Δ2-Cefepime
Synonyms
Δ2-Cefepime;Δ2-Cefepime;Δ2-CefepiMe Etherate;Cefepime Δ - 3 Isomer;Cefepime Δ - 3 Isomer;Δ2-CefepiMe Etherate Dihydrochloride Salt;1-[[(6R,7R)-7-[[(2Z)-2-(2-AMino-4-thiazolyl)-2-(MethoxyiMino)acetyl]aMino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-en-3-yl]Methyl]-1-MethylpyrrolidiniuM Inner Salt Etherate;(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methylpyrrolidin-1-ium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylate,ethoxyethane
CBNumber:
CB02508627
Molecular Formula:
C23H34N6O6S2
Molecular Weight:
554.68266
MDL Number:
MOL File:
88040-25-9.mol
Last updated:2023-09-08 09:40:07

Δ2-Cefepime Properties

Melting point >151°C (dec.)
storage temp. Amber Vial, -20°C Freezer, Under Inert Atmosphere
solubility Water (Slightly)
form Solid
color White to Off-White
InChIKey DBCVQAGQPYVVDA-XVKMNWMGSA-N

Δ2-Cefepime price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC C242743 Δ2-Cefepime 88040-25-9 2.5mg $120 2021-12-16 Buy
AK Scientific 7513DU (6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methylpyrrolidin-1-ium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylate;ethoxyethane 88040-25-9 1mg $211 2021-12-16 Buy
Biosynth Carbosynth FC19856 Delta2-Cefepime etherate 88040-25-9 2mg $218.1 2021-12-16 Buy
Biosynth Carbosynth FC19856 Delta2-Cefepime etherate 88040-25-9 5mg $396.4 2021-12-16 Buy
Biosynth Carbosynth FC19856 Delta2-Cefepime etherate 88040-25-9 10mg $720.8 2021-12-16 Buy
Product number Packaging Price Buy
C242743 2.5mg $120 Buy
7513DU 1mg $211 Buy
FC19856 2mg $218.1 Buy
FC19856 5mg $396.4 Buy
FC19856 10mg $720.8 Buy

Δ2-Cefepime Chemical Properties,Uses,Production

Uses

Δ2-Cefepime is the Δ2-isomer of Cefepime (C242750), a new series of cephalosporins.

Uses

The Δ2-isomer of Cefepime (C242750), a new series of cephalosporins.

Preparation

First, cefepime and N-trimethylsilylacetamide were added to dichloromethane for 0.5 h. Subsequently, triethylamine dissolved in dichloromethane was added to the reaction system between 2-5 °C. Adjust the temperature to 2-5 °C and react for 24 h. After adding water, the aqueous layer was separated, and the aqueous phase was washed with methylene chloride. Wait for the solution to cool to 2-5 °C and adjust the pH=3 with sulfuric acid. Stir the resulting slurry for 2h. Filter to collect the solids and wash with water, adjust the pH=7.5-8.0 with sodium bicarbonate aqueous solution, add carbon, and stir for 30 min. Filter the mixture to collect the filtrate and adjust pH=3 with sulfuric acid. Finally, the solids are filtered and collected, and product Δ2-Cefepime is obtained by washing and drying.
Δ2-Cefepime

Δ2-Cefepime Preparation Products And Raw materials

Raw materials

Preparation Products

Δ2-Cefepime Suppliers

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BOC Sciences
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Δ2-Cefepime Δ2-CefepiMe Etherate 1-[[(6R,7R)-7-[[(2Z)-2-(2-AMino-4-thiazolyl)-2-(MethoxyiMino)acetyl]aMino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-en-3-yl]Methyl]-1-MethylpyrrolidiniuM Inner Salt Etherate Δ2-CefepiMe Etherate Dihydrochloride Salt (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methylpyrrolidin-1-ium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylate,ethoxyethane Cefepime Δ - 3 Isomer Δ2-Cefepime Cefepime Δ - 3 Isomer 88040-25-9 C23H34N6O6S2 Chiral Reagents Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds