Epoxy Fluor 7
- CAS No.
- 863223-43-2
- Chemical Name:
- Epoxy Fluor 7
- Synonyms
- Epoxy Fluor 7;Epoxy Fluor 7 Exclusive;[cyano-(6-methoxynaphthalen-2-yl)methyl] (3-phenyloxiran-2-yl)methyl carbonate;Carbonic acid, cyano(6-methoxy-2-naphthalenyl)methyl [(2R,3R)-3-phenyl-2-oxiranyl]methyl ester, rel-
- CBNumber:
- CB02590956
- Molecular Formula:
- C23H19NO5
- Molecular Weight:
- 389.4
- MDL Number:
- MOL File:
- 863223-43-2.mol
Epoxy Fluor 7 price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 10008610 | Epoxy Fluor 7 ≥98% | 863223-43-2 | 1mg | $40 | 2024-03-01 | Buy |
| Cayman Chemical | 10008610 | Epoxy Fluor 7 ≥98% | 863223-43-2 | 5mg | $180 | 2024-03-01 | Buy |
| Cayman Chemical | 10008610 | Epoxy Fluor 7 ≥98% | 863223-43-2 | 10mg | $299 | 2024-03-01 | Buy |
| Cayman Chemical | 10008610 | Epoxy Fluor 7 ≥98% | 863223-43-2 | 50mg | $1498 | 2023-06-20 | Buy |
| AK Scientific | 1692AH | Cyano(6-methoxy-2-napthalenyl)methyl[(2,3)-3-phenyloxiranyl]methylester,carbonicacid | 863223-43-2 | 5mg | $318 | 2021-12-16 | Buy |
Epoxy Fluor 7 Chemical Properties,Uses,Production
Description
Soluble epoxide hydrolase (sEH) catalyzes the conversion of epoxyeicosatrienoic acids (EpETrEs) to the corresponding DiHETrEs thereby diminishing their vasodilator activity.1 Inhibitors of sEH may therefore have clinical utility for treating hypertension and systemic inflammation.2,3 Epoxy fluor 7 is a sensitive fluorescent substrate for soluble epoxide hydrolase (sEH) that can be used to monitor the activity of both human and mouse enzymes.4 Hydrolysis of the substrate epoxide yields a highly fluorescent product that can be monitored at excitation and emission wavelengths of 330 and 465 nm, respectively. Epoxy fluor 7 is more stable in aqueous solution and offers about 2-
References
1. Yu, Z., Xu, F., Huse, L.M., et al. Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids Circ. Res. 87(11),992-998(2000).
2. Imig, J.D., Zhao, X., Zaharis, C.Z., et al. An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in salt-
3. Schmelzer, K.R., Kubala, L., Newman, J.W., et al. Soluble epoxide hydrolase is a therapeutic target for acute inflammation Proc. Natl. Acad. Sci. USA 102(28),9772-9777(2005).
4. Jones, P.D., Wolf, N.M., Morisseau, C., et al. Fluorescent substrates for soluble epoxide hydrolase and application to inhibition studies Anal. Biochem. 343,66-75(2005).
Epoxy Fluor 7 Preparation Products And Raw materials
Raw materials
Preparation Products
Epoxy Fluor 7 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8739 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 28091 | 58 |