ChemicalBook >> CAS DataBase List >>Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]-
Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]-
- CAS No.
- 211555-08-7
- Chemical Name:
- Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]-
- Synonyms
- Janex 3;WHI-P180, >98%;WHI-P180(Janex 3);WHI P180;JANEX3;WHIP180;JANEX-3;3-(6,7-dimethoxyquinazolin-4-ylamino)phenol;3-[(6,7-Dimethoxy-4-quinazolinyl)amino]phenol;Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]-;3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol (Related Reference);WHI-P-180,HER1,Janex3,WHI P180,RET,EGFR,Vascular endothelial growth factor receptor,Inhibitor,Janex-3,WHIP180,inhibit,WHI-P180,VEGFR,ErbB-1,Epidermal growth factor receptor
- CBNumber:
- CB02667258
- Molecular Formula:
- C16H15N3O3
- Molecular Weight:
- 297.31
- MDL Number:
- MFCD02683970
- MOL File:
- 211555-08-7.mol
- MSDS File:
- SDS
Last updated:2024-07-02 08:54:57
Boiling point | 476.5±40.0 °C(Predicted) |
---|---|
Density | 1.336±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C(protect from light) |
solubility | DMSO : 25 mg/mL (84.09 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble) |
form | Powder |
pka | 9.58±0.10(Predicted) |
color | White to off-white |
Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]- price More Price(34)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 681500 | WHI-P180 A potent inhibitor of lgE-mediated mast cell responses to allergens in vitro and in vivo. | 211555-08-7 | 1MG | $259 | 2024-03-01 | Buy |
Cayman Chemical | 23452 | WHI-P180 ≥98% | 211555-08-7 | 500μg | $93 | 2024-03-01 | Buy |
Cayman Chemical | 23452 | WHI-P180 ≥98% | 211555-08-7 | 1mg | $176 | 2024-03-01 | Buy |
Cayman Chemical | 23452 | WHI-P180 ≥98% | 211555-08-7 | 5mg | $684 | 2024-03-01 | Buy |
ChemScene | CS-1702 | WHI-P180 99.76% | 211555-08-7 | 50mg | $1080 | 2021-12-16 | Buy |
Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]- Chemical Properties,Uses,Production
Biological Activity
WHI-P180 is an inhibitor of multiple kinases with IC50 values of 4.5 nM and 66 nM for RET (c-RET) and KDR, respectively.
in vivo
WHI-P180 is also an active inhibitor of IgE-mediated mast cell responses. The elimination half-life of WHI-P180 in CD-1 mice (BALB/c mice) following iv, ip, or po administration is less than 10 min. Systemic clearance of WHI-P180 is 6742 mL/h/kg in CD-I mice and 8188 mL/h/kg in BALB/c mice. Notably, WHI-P180, when administered in two consecutive nontoxic ip bolus doses of 25 mg/kg, inhibits IgE/antigen-induced vascular hyperpermeability in a well-characterized murine model of passive cutaneous anaphylaxis.
target
Target | Value |
RET (Cell-free assay) | 4.5 nM |
KDR (Cell-free assay) | 66 nM |
Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]- Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 81)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29897 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 | cbc@coresyn.com | China | 9991 | 58 |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
View Lastest Price from Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]- manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2019-09-06 | Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]-
211555-08-7
|
US $1.00 / KG | 1KG | 98% | 20kg | Career Henan Chemical Co |
- Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]-
211555-08-7
- US $1.00 / KG
- 98%
- Career Henan Chemical Co
211555-08-7(Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]-)Related Search:
Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]-
3-[(6,7-Dimethoxy-4-quinazolinyl)amino]phenol
Janex 3
3-(6,7-dimethoxyquinazolin-4-ylamino)phenol
3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol (Related Reference)
WHI P180;JANEX3;WHIP180;JANEX-3
WHI-P180(Janex 3)
WHI-P180, >98%
WHI-P-180,HER1,Janex3,WHI P180,RET,EGFR,Vascular endothelial growth factor receptor,Inhibitor,Janex-3,WHIP180,inhibit,WHI-P180,VEGFR,ErbB-1,Epidermal growth factor receptor
211555-08-7
Inhibitors