ChemicalBook >> CAS DataBase List >>Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-
Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-
- CAS No.
- 1132709-16-0
- Chemical Name:
- Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-
- Synonyms
- Bortizomib SR-OH;(1S,2R)-BortezoMib;Bortezomib (1R,2R)Isomer;Bortezomib S,R Enantiomer;Bortezomib (1S, 2R)-Isomer;(1S,2R)-Bortezomib Impurity;Bortezomib S,R-Isomer Impurity;Bortezomib impurities (R, S-isomer);Bortezomib Impurity (1S,2R - Isomer);Bortezomib impurity 2/(1S,2R)-Bortezomib
- CBNumber:
- CB02677165
- Molecular Formula:
- C19H25BN4O4
- Molecular Weight:
- 384.24
- MDL Number:
- MFCD09749895
- MOL File:
- 1132709-16-0.mol
Last updated:2023-05-15 10:43:59
Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]- Properties
Density | 1.214±0.06 g/cm3(Predicted) |
---|---|
solubility | Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly) |
pka | 9.66±0.43(Predicted) |
form | Solid |
color | White to Off-White |
Stability | Hygroscopic, Light sensitive, Moisture sensitive |
Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]- price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | B675710 | (1S,2R)-Bortezomib | 1132709-16-0 | 50mg | $375 | 2021-12-16 | Buy |
Chemenu | CM205039 | ((S)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid 95%+ | 1132709-16-0 | 100mg | $668 | 2021-12-16 | Buy |
Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]- Chemical Properties,Uses,Production
Uses
(1S,3R)-Bortezomib is an diastereomer of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway
Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]- Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 63)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8647 | 58 |
sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12373 | 58 |
China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11922 | 58 |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
Suzhou ARTK Medchem Co., Ltd. | +86-512-68323658 +86-18168183658 | sales1@artkmedchem.com | China | 39004 | 58 |
Guangzhou PI PI Biotech Inc | 020-81716320 +86-13602409664 | Sales@pipitech.com | China | 3633 | 55 |
1132709-16-0(Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-)Related Search:
2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris-
BORTEZOMIB-PINANEDIOL
2-PyrazinecarboxaMide, N-[(1S)-2-[[(1R)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]-
Bortezomib Impurity 2 (Mixture of (1S,2R)-Isomer and (1R,2R)-Isomer)
2-PyrazinecarboxaMide, N-[(1S)-2-[[(1S)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]-
N-((S)-1-(((R)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
Bortezomib Impurity 1 (R,S-Isomer)
BortezoMib IMpurity 2 (RR-IsoMer)
(S)-N-(1-(3-MethylbutanaMido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
bortezoMib iMpurity H
Bortezomib
((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid
(S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID
(aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate
1of4
Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-
(1S,2R)-BortezoMib
(S)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butylboronic acid
N-(2-Pyrazinecarbonyl)-D-phenylalanine-D-leucine boronic anhydride
Bortezomib Impurity (1S,2R - Isomer)
Bortezomib impurity 2/(1S,2R)-Bortezomib
Bortezomib (1R,2R)Isomer
(1S,2R)-Bortezomib Impurity
Bortezomib impurities (R, S-isomer)
Bortezomib (1S, 2R)-Isomer
(1s) - 3-methyl-1 - [(2R) - 1-oxo-3-phenyl-2 - [(pyrazinoyl) - amino] propyl] amino] butyl] boric acid
Bortizomib SR-OH
Bortezomib S,R-Isomer Impurity
(1S,2R) BortezomibQ: What is
(1S,2R) Bortezomib Q: What is the CAS Number of
(1S,2R) Bortezomib Q: What is the storage condition of
(1S,2R) Bortezomib Q: What are the applications of
(1S,2R) Bortezomib
Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2
Bortezomib S,R Enantiomer
1132709-16-0
Chiral Reagents, Boron Derivatives, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals