ChemicalBook >> CAS DataBase List >>2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris-

2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris-

2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris- structure

CAS No.: 390800-88-1

Chemical Name:: 2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris-

Synonyms: Bortezomib-d15;Bortezomib Trimer;(1R,2S)-Bortezomib;Bortezomib trimer API;Bortezomib ((1R,2S)-Bortezomib);Bortezomib impurity 10/(1R,2S)-Bortezomib;Bortezomib Trimer ((1R,2S)-Bortezomib Trimer);N,N',N''-((2S,2'S,2''S)-(((1R,1'R,1''R)-(1,3,5,2,4,6-Trioxatriborinane-2,4,6-triyl)tris(3-methylbutane-1,1-diyl))tris(azanediyl))tris(1-oxo-3-phenylpropane-1,2-diyl))tris(pyrazine-2-carboxamide)（Bortezomib Impurity）

CBNumber:: CB92563421

Molecular Formula:: C57H69B3N12O9

Molecular Weight:: 1098.67

MDL Number:: MFCD32644677

MOL File:: 390800-88-1.mol

MSDS File:: SDS

Last updated:2023-05-15 10:43:59

Request For Quotation

2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris- Properties

Boiling point	1277.7±65.0 °C(Predicted)
Density	1.26±0.1 g/cm3(Predicted)
storage temp.	-20°C Freezer
solubility	DMSO (Slightly), Methanol (Slightly)
pka	11.46±0.46(Predicted)
form	Solid
color	White to Off-White
FDA UNII	264LX948L0

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS08,GHS09,GHS06
Signal word	Danger
Hazard statements	H361-H300-H372-H315-H411-H319
Precautionary statements	P201-P202-P281-P308+P313-P405-P501-P260-P264-P270-P314-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P310-P321-P330-P405-P501

2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris- price More Price(4)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	22367	Bortezomib-d15	390800-88-1	500μg	$166	2024-03-01	Buy
Cayman Chemical	22367	Bortezomib-d15	390800-88-1	1mg	$313	2024-03-01	Buy
TRC	B675720	BortezomibTrimer	390800-88-1	5mg	$155	2021-12-16	Buy
Chemenu	CM334947	N,N'',N''''-((1S,1''S,1''''S)-(((1R,1''R,1''''R)-(1,3,5,2,4,6-Trioxatriborinane-2,4,6-triyl)tris(3-methylbutane-1,1-diyl))tris(azanediyl))tris(2-oxo-1-phenylethane-2,1-diyl))tris(pyrazine-2-carboxamide) 95%+	390800-88-1	1g	$1235	2021-12-16	Buy

Product number	Packaging	Price	Buy
22367	500μg	$166	Buy
22367	1mg	$313	Buy
B675720	5mg	$155	Buy
CM334947	1g	$1235	Buy

2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris- Chemical Properties,Uses,Production

Uses

Bortezomib Trimer is derived from Bortezomib (B675700), which is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.

2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris- Preparation Products And Raw materials

Raw materials

Preparation Products

2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris- Suppliers

Global( 48)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10326	58
Shanghai Rochi Pharmaceutical Co.,Ltd.	21-38751876 +8615000076078	info@rochipharma.com	China	431	58
ZHEJIANG JIUZHOU CHEM CO., LTD	+86-0576225566889 +86-13454675544	admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com	China	19947	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
Guangzhou PI PI Biotech Inc	+86-020-81716320 +86-13602409664	Sales@pipitech.com	China	3635	55
Shanghai Fuhe Chemistry Technology Co., Ltd.	0086-21-67651709	cfx759@hotmail.com	China	410	57
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
S.Z. PhyStandard Bio-Tech. Co., Ltd.	0755-4000505016 13380397412	3001272453@qq.com	China	4963	50
ChemStrong Scientific Co.,Ltd	0755-0755-66853366 13670046396	sales@chem-strong.com	China	18018	56

Supplier	Advantage
Standardpharm Co. Ltd.	58
Hubei Ipure Biology Co., Ltd	58
Shanghai Rochi Pharmaceutical Co.,Ltd.	58
ZHEJIANG JIUZHOU CHEM CO., LTD	58
China National Standard Pharmaceutical Corporation Limited	58
Guangzhou PI PI Biotech Inc	55
Shanghai Fuhe Chemistry Technology Co., Ltd.	57
BOC Sciences	65
S.Z. PhyStandard Bio-Tech. Co., Ltd.	50
ChemStrong Scientific Co.,Ltd	56

390800-88-1(2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris-)Related Search:

BORTEZOMIB-PINANEDIOL 2-PyrazinecarboxaMide, N-[(1S)-2-[[(1R)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]- ((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid Bortezomib Impurity 2 (Mixture of (1S,2R)-Isomer and (1R,2R)-Isomer) 2-PyrazinecarboxaMide, N-[(1S)-2-[[(1S)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]-

N-((S)-1-(((R)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide ((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid Bortezomib Impurity 1 (R,S-Isomer) Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]- BortezoMib IMpurity 2 (RR-IsoMer)

1of2

(1R,2S)-Bortezomib Bortezomib-d15 Bortezomib impurity 10/(1R,2S)-Bortezomib Bortezomib Trimer Bortezomib ((1R,2S)-Bortezomib) Bortezomib trimer API Bortezomib Trimer ((1R,2S)-Bortezomib Trimer) N,N',N''-((2S,2'S,2''S)-(((1R,1'R,1''R)-(1,3,5,2,4,6-Trioxatriborinane-2,4,6-triyl)tris(3-methylbutane-1,1-diyl))tris(azanediyl))tris(1-oxo-3-phenylpropane-1,2-diyl))tris(pyrazine-2-carboxamide)（Bortezomib Impurity） 390800-88-1 C57H69B3N12O9