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ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris-

2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris-

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2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris- Suppliers list
Company Name: Standardpharm Co. Ltd.
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Products Intro: Product Name:Bortezomib Impurity 38
CAS:390800-88-1
Purity:0.99 Package:10mg;25mg;50mg;100mg
Company Name: Hubei Ipure Biology Co., Ltd
Tel: +8613367258412
Email: ada@ipurechemical.com
Products Intro: Product Name:Bortezomib
CAS:390800-88-1
Purity:99% Package:100mg;500mg;1g;5g;10g
Company Name: Shanghai Rochi Pharmaceutical Co.,Ltd.
Tel: 21-38751876 +8615000076078
Email: info@rochipharma.com
Products Intro: Product Name:Bortezomib
CAS:390800-88-1
Purity:99%min Package:1kg 5kg 10kg 25kg
Company Name: China National Standard Pharmaceutical Corporation Limited
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Email: overseasales@yongstandards.com
Products Intro: Product Name:Bortezomib Impurity 38
CAS:390800-88-1
Purity:0.95 Package:Vials
Company Name: Guangzhou PI PI Biotech Inc  
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Email: Sales@pipitech.com
Products Intro: Product Name:Bortezomib Trimer
CAS:390800-88-1
Purity:90%+ Package:10mg, 25mg, 50mg, 100mg, Other scale please email Sales@pipitech.com Remarks:N,N’,N’’-[2,4,6-Boroxintriyltris[[(1R)-3-methylbutylidene]imino[(1S)-2-oxo-1-(phenylmethyl)-2,1-ethanediyl]]]tris[2-pyrazinecarboxamide]
2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris- Basic information
Product Name:2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris-
Synonyms:(1R,2S)-Bortezomib;Bortezomib-d15;Bortezomib impurity 10/(1R,2S)-Bortezomib;Bortezomib Trimer;Bortezomib ((1R,2S)-Bortezomib);Bortezomib trimer API;Bortezomib Trimer ((1R,2S)-Bortezomib Trimer);N,N',N''-((2S,2'S,2''S)-(((1R,1'R,1''R)-(1,3,5,2,4,6-Trioxatriborinane-2,4,6-triyl)tris(3-methylbutane-1,1-diyl))tris(azanediyl))tris(1-oxo-3-phenylpropane-1,2-diyl))tris(pyrazine-2-carboxamide)（Bortezomib Impurity）
CAS:390800-88-1
MF:C57H69B3N12O9
MW:1098.67
EINECS:816-310-1
Product Categories:
Mol File:390800-88-1.mol
2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris- Structure
2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris- Chemical Properties
Boiling point 1277.7±65.0 °C(Predicted)
density 1.26±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO (Slightly), Methanol (Slightly)
pka11.46±0.46(Predicted)
form Solid
color White to Off-White
Safety Information
MSDS Information
2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris- Usage And Synthesis
UsesBortezomib Trimer is derived from Bortezomib (B675700), which is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.
2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris- Preparation Products And Raw materials
Tag:2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris-(390800-88-1) Related Product Information
BORTEZOMIB-PINANEDIOL 2-PyrazinecarboxaMide, N-[(1S)-2-[[(1R)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]- ((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid Bortezomib Impurity 2 (Mixture of (1S,2R)-Isomer and (1R,2R)-Isomer) 2-PyrazinecarboxaMide, N-[(1S)-2-[[(1S)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]- N-((S)-1-(((R)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide ((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid Bortezomib Impurity 1 (R,S-Isomer) Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]- BortezoMib IMpurity 2 (RR-IsoMer)