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Product Name:Bortezomib Trimer CAS:390800-88-1 Purity:90%+ Package:10mg, 25mg, 50mg, 100mg, Other scale please email Sales@pipitech.com Remarks:N,N’,N’’-[2,4,6-Boroxintriyltris[[(1R)-3-methylbutylidene]imino[(1S)-2-oxo-1-(phenylmethyl)-2,1-ethanediyl]]]tris[2-pyrazinecarboxamide]
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| 2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris- Basic information |
Product Name: | 2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris- | Synonyms: | (1R,2S)-Bortezomib;Bortezomib-d15;Bortezomib impurity 10/(1R,2S)-Bortezomib;Bortezomib Trimer;Bortezomib ((1R,2S)-Bortezomib);Bortezomib trimer API;Bortezomib Trimer ((1R,2S)-Bortezomib Trimer);N,N',N''-((2S,2'S,2''S)-(((1R,1'R,1''R)-(1,3,5,2,4,6-Trioxatriborinane-2,4,6-triyl)tris(3-methylbutane-1,1-diyl))tris(azanediyl))tris(1-oxo-3-phenylpropane-1,2-diyl))tris(pyrazine-2-carboxamide)(Bortezomib Impurity) | CAS: | 390800-88-1 | MF: | C57H69B3N12O9 | MW: | 1098.67 | EINECS: | 816-310-1 | Product Categories: | | Mol File: | 390800-88-1.mol | ![2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris- Structure](CAS/20180808/GIF/390800-88-1.gif) |
| 2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris- Chemical Properties |
Boiling point | 1277.7±65.0 °C(Predicted) | density | 1.26±0.1 g/cm3(Predicted) | storage temp. | -20°C Freezer | solubility | DMSO (Slightly), Methanol (Slightly) | pka | 11.46±0.46(Predicted) | form | Solid | color | White to Off-White |
| 2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris- Usage And Synthesis |
Uses | Bortezomib Trimer is derived from Bortezomib (B675700), which is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway. |
| 2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris- Preparation Products And Raw materials |
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