ChemicalBook >> CAS DataBase List >>NS 3623
NS 3623
- CAS No.
- 343630-41-1
- Chemical Name:
- NS 3623
- Synonyms
- NS 3623;1-[4-bromo-2-(2H-tetrazol-5-yl)phenyl]-3-[3-(trifluoromethyl)phenyl]urea;1-(4-Bromo-2-(1H-tetrazol-5-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea;N-[4-Bromo-2-(1H-tetrazol-5-yl-phenyl]-N'-[3-(trifluoromethyl)phenyl]-urea;Urea, N-[4-bromo-2-(2H-tetrazol-5-yl)phenyl]-N'-[3-(trifluoromethyl)phenyl]-;channels,NS 3623,midmyocardial,cardiomyocytes,current,ion,NS3623,Potassium Channel,canine,Potassium,KcsA,Inhibitor,inhibit,cells,Antiarrhythmic,effect,NS-3623
- CBNumber:
- CB02694337
- Molecular Formula:
- C15H10BrF3N6O
- Molecular Weight:
- 427.18
- MDL Number:
- MOL File:
- 343630-41-1.mol
- MSDS File:
- SDS
Last updated:2024-07-02 08:54:57
| Density | 1.759±0.06 g/cm3(Predicted) |
|---|---|
| storage temp. | Store at -20°C |
| solubility | Soluble to 100 mM in DMSO |
| form | Powder |
| pka | 3.95±0.10(Predicted) |
| color | White to off-white |
| FDA UNII | J9HB2T5SS4 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301-H413 |
| Precautionary statements | P264-P270-P273-P301+P310+P330-P405-P501 |
NS 3623 price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML2843 | NS3623 ≥98% (HPLC) | 343630-41-1 | 5MG | $118 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML2843 | NS3623 ≥98% (HPLC) | 343630-41-1 | 25MG | $476 | 2024-03-01 | Buy |
| Tocris | 4462 | NS3623 ≥99%(HPLC) | 343630-41-1 | 10 | $233 | 2021-12-16 | Buy |
| Tocris | 4462 | NS3623 ≥99%(HPLC) | 343630-41-1 | 50 | $980 | 2021-12-16 | Buy |
| TRC | N900250 | NS3623 | 343630-41-1 | 10mg | $160 | 2021-12-16 | Buy |
NS 3623 Chemical Properties,Uses,Production
Uses
NS 3623 selectively activates the human ether-a-go-go related gene (hERG) potassium channel which mediates the repolarizing cardiac current IKr. NS 3623 an IKr agonist, cause QT interval prolongation, increasing the risk of dangerous ventricular fibrillations, eventually leading to sudden cardiac death.
storage
Store at +4°C
NS 3623 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 58)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Wuhan Shanhai Zhihe Biotechnology Co., Ltd. | 17771424646 | shoubull@126.com | China | 967 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94717 | 76 |
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8073 | 58 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4252 | 55 | |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
NS 3623
1-[4-bromo-2-(2H-tetrazol-5-yl)phenyl]-3-[3-(trifluoromethyl)phenyl]urea
N-[4-Bromo-2-(1H-tetrazol-5-yl-phenyl]-N'-[3-(trifluoromethyl)phenyl]-urea
1-(4-Bromo-2-(1H-tetrazol-5-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea
channels,NS 3623,midmyocardial,cardiomyocytes,current,ion,NS3623,Potassium Channel,canine,Potassium,KcsA,Inhibitor,inhibit,cells,Antiarrhythmic,effect,NS-3623
Urea, N-[4-bromo-2-(2H-tetrazol-5-yl)phenyl]-N'-[3-(trifluoromethyl)phenyl]-
343630-41-1
C15H10BrF3N6O
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