Kibdelone C
- CAS No.
- 934464-79-6
- Chemical Name:
- Kibdelone C
- Synonyms
- Kibdelone C;2H-[1]Benzopyrano[2',3':6,7]naphth[2,1-g]isoquinoline-1,14-dione, 4-chloro-6,7,10,11,12,13-hexahydro-5,10,12,13,15,16-hexahydroxy-8-methoxy-2-methyl-3-propyl-, (10S,12S,13R)-
- CBNumber:
- CB02703741
- Molecular Formula:
- C29H28ClNO10
- Molecular Weight:
- 585.99
- MDL Number:
- MOL File:
- 934464-79-6.mol
- MSDS File:
- SDS
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Kibdelone C Chemical Properties,Uses,Production
Description
Kibdelone C is a member of a family of natural heterocyclic polyketides first isolated from a soil actinomycete, Kibdelosporangium. Kibdelones have been described as having potent and selective cytotoxicity against a panel of human tumor cell lines, and kibdelone C has low nanomolar effectiveness in these assays. Kibdelone C disrupts the actin cytoskeleton without directly binding actin or affecting its polymerization in vitro.
Uses
Kibdelone C is the major analogue of a potent antitumor complex.
Uses
Kibdelone C is the major analogue of a potent antitumor complex isolated from Kibdelosporangium sp.. Structurally, kibdelone C is related to lysolipin and albofungin, however no comparative investigation of this class has been reported. The mode of action and pharmacology of the kibdelones has received little attention.
Uses
Kibdelone C is the major analogue of a potent antitumour complex isolated from Kibdelosporangium sp.. Structurally, kibdelone C is related to lysolipin and albofungin, however no comparative investigation of this class has been reported. The mode of action and pharmacology of the kibdelones has received little attention.
Kibdelone C Preparation Products And Raw materials
Raw materials
Preparation Products
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