키브델론C

키브델론C
키브델론C 구조식 이미지
카스 번호:
934464-79-6
한글명:
키브델론C
동의어(한글):
키브델론C
상품명:
Kibdelone C
동의어(영문):
Kibdelone C;2H-[1]Benzopyrano[2',3':6,7]naphth[2,1-g]isoquinoline-1,14-dione, 4-chloro-6,7,10,11,12,13-hexahydro-5,10,12,13,15,16-hexahydroxy-8-methoxy-2-methyl-3-propyl-, (10S,12S,13R)-
CBNumber:
CB02703741
분자식:
C29H28ClNO10
포뮬러 무게:
585.99
MOL 파일:
934464-79-6.mol

키브델론C 속성

녹는점
265-267 °C(Solv: benzene (71-43-2))
끓는 점
968.8±65.0 °C(Predicted)
밀도
1.71±0.1 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
물리적 상태
고체
산도 계수 (pKa)
6.44±0.70(Predicted)

안전

키브델론C C화학적 특성, 용도, 생산

개요

Kibdelone C is a member of a family of natural heterocyclic polyketides first isolated from a soil actinomycete, Kibdelosporangium. Kibdelones have been described as having potent and selective cytotoxicity against a panel of human tumor cell lines, and kibdelone C has low nanomolar effectiveness in these assays. Kibdelone C disrupts the actin cytoskeleton without directly binding actin or affecting its polymerization in vitro.

용도

Kibdelone C is the major analogue of a potent antitumour complex isolated from Kibdelosporangium sp.. Structurally, kibdelone C is related to lysolipin and albofungin, however no comparative investigation of this class has been reported. The mode of action and pharmacology of the kibdelones has received little attention.

키브델론C 준비 용품 및 원자재

원자재

준비 용품


키브델론C 공급 업체

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