Mn(III) Meso-Tetra (4-carboxyphenyl) porphine chloride
- CAS No.
- 55266-18-7
- Chemical Name:
- Mn(III) Meso-Tetra (4-carboxyphenyl) porphine chloride
- Synonyms
- Mn(III)TBAP (chloride);MnTBAP chloride, 10 mM in DMSO;MnTBAP chloride, Superoxide dismutase (SOD) mimetic;Mn(III) Meso-Tetra (4-carboxyphenyl) porphine chloride;Manganese(III) meso-tetra(4-carboxyphenyl)porphine chloride;5,10,15,20-Tetrakis(4-carboxyphenyl)porphyrin-Mn(III) chloride (MnTBAP);5,10,15,20-Tetrakis(4-carboxyphenyl)-21H,23H-porphine]manganese(III) chloride
- CBNumber:
- CB02709192
- Molecular Formula:
- C48H28ClMnN4O8
- Molecular Weight:
- 879.148969
- MDL Number:
- MFCD06227760
- MOL File:
- 55266-18-7.mol
- MSDS File:
- SDS
| storage temp. | -20C |
|---|---|
| solubility | Soluble in 0.1M NaOH |
| form | Brown solid |
| color | Black |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in 0.1M NaOH may be stored at -20° for up to 1 month. |
| FDA UNII | 5J7YG8LCQ4 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
Mn(III) Meso-Tetra (4-carboxyphenyl) porphine chloride price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 475870 | MnTBAP - Calbiochem MnTBAP, CAS 55266-18-7, is a cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger., Cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger. |
55266-18-7 | 25mg | $111 | 2024-03-01 | Buy |
| Cayman Chemical | 75850 | Mn(III)TBAP (chloride) | 55266-18-7 | 25mg | $41 | 2024-03-01 | Buy |
| Cayman Chemical | 75850 | Mn(III)TBAP (chloride) | 55266-18-7 | 50mg | $78 | 2024-03-01 | Buy |
| Cayman Chemical | 75850 | Mn(III)TBAP (chloride) | 55266-18-7 | 10mg | $19 | 2024-03-01 | Buy |
| Cayman Chemical | 75850 | Mn(III)TBAP (chloride) | 55266-18-7 | 100mg | $138 | 2024-03-01 | Buy |
Mn(III) Meso-Tetra (4-carboxyphenyl) porphine chloride Chemical Properties,Uses,Production
Description
MnTBAP (55266-18-7) is a superoxide dismutase (SOD) mimetic. Potent peroxynitrite scavenger but does not scavenge nitric oxide.
Uses
MnTBAP chloride is a cell permeable superoxide dismutase mimetic and peroxynitrite scavenger.
General Description
Cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger. Protects endothelial cells in a dose-dependent manner (EC50 ~40 μM) against paraquat (2 mM). Inhibits the oxidation of Dihydrorhodamine 123 (Cat. No. 309825) by peroxynitrite, but does not scavenge nitric oxide (NO).
Biochem/physiol Actions
Cell permeable: yes
in vivo
MnTBAP chloride (10 mg/kg; IP; three times per week for twelve weeks) attenuates renal fibrosis in 5/6 Nx mice[1].
| Animal Model: | C57BL/6J mice with 5/6 nephrectomy (Nx)[1] |
| Dosage: | 10?mg/kg |
| Administration: | IP; three times per week for twelve weeks |
| Result: | Attenuated renal fibrosis in 5/6 Nx mice and reduced protein expressions of fibronectin, collagen III in remnant kidneys. |
IC 50
NFκB
References
1) Szabo et al. (1996), Evaluation of the relative contribution of nitric oxide and peroxynitrite to the suppression of mitochondrial resporation in immunostimulated macrophages using a manganese mesoporphyrin superoxide dismutase mimetic and peroxynitrite scavenger; FEBS Lett., 381 82 2) Faulkner et al. (1994), Stable MN(III) porphyrins mimic superoxide dismutase in vitro and substitute for it in vivo; J. Biol. Chem., 269 23471
Mn(III) Meso-Tetra (4-carboxyphenyl) porphine chloride Preparation Products And Raw materials
Raw materials
Preparation Products
Mn(III) Meso-Tetra (4-carboxyphenyl) porphine chloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Aslee Biopharmaceuticals, Inc. | 28-85305008 | CHINA | 964 | 58 | |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12162 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| SUZHOU SENFEIDA CHEMICAL CO.,LTD | +86-0512-83500002 +8618501500038 | 3899766280@qq.com | China | 26362 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| J & K SCIENTIFIC LTD. | 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chongqing Xingcan Pharmaceutical Technology Co., Ltd. | 15523000485 | xingcanyaoye@sina.com | China | 1686 | 58 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 | shenlinxing@macklin.cn | China | 15874 | 55 |
| Chengdu Aslee Biopharmaceuticals, Inc | 028-85305008 02885305008 | 2306208234@qq.com | China | 1006 | 50 |
View Lastest Price from Mn(III) Meso-Tetra (4-carboxyphenyl) porphine chloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-16 | MnTBAP chloride
55266-18-7
|
US $34.00-55.00 / mg | 10g | TargetMol Chemicals Inc. |
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- MnTBAP chloride
55266-18-7
- US $34.00-55.00 / mg
- TargetMol Chemicals Inc.