ChemicalBook >> CAS DataBase List >>FMoc-Val-Cit-PAB
FMoc-Val-Cit-PAB
- CAS No.
- 159858-22-7
- Chemical Name:
- FMoc-Val-Cit-PAB
- Synonyms
- Fmoc-Val-Cit-PAB-OH;(9H-fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate;FMoc-Val-Cit-PAB;Fomc-Val-Cit-PAB;TrastuzumabImpurity2;Fmoc-L-Val-Cit-PAB-OH;Fmoc-val-citrulline-para-aminobenzyl-OH;Trastuzumab Impurity 2 (Fmoc-Val-Cit-PAB-OH);4-(N-((9H-fluoren-9-yl)methoxycarbonyl)-L-valinyl-D-citrullinamido)benzyl alcohol;N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide
- CBNumber:
- CB02730901
- Molecular Formula:
- C33H39N5O6
- Molecular Weight:
- 601.69
- MDL Number:
- MFCD22417106
- MOL File:
- 159858-22-7.mol
- MSDS File:
- SDS
Last updated:2024-05-24 15:44:31
Melting point | 204 °C(dec.) |
---|---|
Boiling point | 914.2±65.0 °C(Predicted) |
Density | 1.276±0.06 g/cm3(Predicted) |
storage temp. | Sealed in dry,Store in freezer, under -20°C |
form | powder to crystal |
pka | 10.63±0.46(Predicted) |
color | White to Almost white |
CAS DataBase Reference | 159858-22-7 |
FMoc-Val-Cit-PAB price More Price(18)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TCI Chemical | F1223 | Fmoc-Val-Cit-PAB-OH | 159858-22-7 | 25MG | $16 | 2024-03-01 | Buy |
TCI Chemical | F1223 | Fmoc-Val-Cit-PAB-OH | 159858-22-7 | 100MG | $39 | 2024-03-01 | Buy |
AK Scientific | 2998DP | Fmoc-Val-Cit-PAB | 159858-22-7 | 25mg | $259 | 2021-12-16 | Buy |
ChemScene | CS-5170 | Fmoc-Val-Cit-PAB 97.15% | 159858-22-7 | 250mg | $300 | 2021-12-16 | Buy |
Iris Biotech GmbH | ADC1030 | Fmoc-Val-Cit-PAB | 159858-22-7 | 250mg | $303.75 | 2021-12-16 | Buy |
FMoc-Val-Cit-PAB Chemical Properties,Uses,Production
Uses
Fmoc-Val-Cit-PAB is a commonly used bridge for a degradable antibody-conjugated drug (ADC).
Description
Fmoc-Val-Cit-PAB-OH is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. Fmoc can be deprotected under basic condition.
FMoc-Val-Cit-PAB Preparation Products And Raw materials
Global( 221)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Chemtour Biotech Co., Ltd | +8617327281506 | market@chemtour.com | China | 1460 | 58 |
Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3002 | 58 |
Hangzhou FandaChem Co.,Ltd. | +8615858145714 | FandaChem@Gmail.com | China | 9084 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32956 | 60 |
Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 965 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10311 | 58 |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
Jurong Coupling Biotechnology Co., Ltd. | 13656108824 | coupling278191416@hotmail.com | CHINA | 184 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29810 | 58 |
Related articles
- FMoc-Val-Cit-PAB: Applications of FMoc-Val-Cit-PAB in Antibody-Drug Conjugates and Its Synthesis Method
- FMoc-Val-Cit-PAB is a peptide conjugate with Val-Cit linker and PAB moiety, enhancing ADC stability and cytotoxicity in target....
- Apr 22,2024
- FMoc-Val-Cit-PAB——Storage and operation
- The molecular formula of Fmoc-Val-Cit-PAB is C33H39N5O6, and the exact molecular weight is 601.6692668199539. Its Catalog No. ....
- Feb 25,2020
View Lastest Price from FMoc-Val-Cit-PAB manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-12-24 | FMoc-Val-Cit-PAB
159858-22-7
|
US $10.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co.,Ltd | ||
2024-03-29 | Fmoc-Val-Cit-PAB-OH
159858-22-7
|
US $0.00 / g | 10g | >95.00% | 10g | Xian confluore Biological Technology Co., Ltd. | ||
2022-10-14 | FMoc-Val-Cit-PAB
159858-22-7
|
US $0.00-0.00 / KG | 1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
- FMoc-Val-Cit-PAB
159858-22-7
- US $10.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
- Fmoc-Val-Cit-PAB-OH
159858-22-7
- US $0.00 / g
- >95.00%
- Xian confluore Biological Technology Co., Ltd.
- FMoc-Val-Cit-PAB
159858-22-7
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
159858-22-7(FMoc-Val-Cit-PAB)Related Search:
FMoc-Val-Cit-PAB
L-Ornithinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-
(9H-fluoren-9-yl)methyl((S)-1-((())-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate
(9H-fluoren-9-yl)methyl N-[(1S)-1-{[(1S)-4-(carbamoylamino)-1-{[4-(hydroxymethyl)phenyl]carbamoyl}butyl]carbamoyl}-2-methylpropyl]carbamate
Fmoc-val-citrulline-para-aminobenzyl-OH
(9H-fluoren-9-yl)methyl ((2S)-1-((1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate
4-(N-((9H-fluoren-9-yl)methoxycarbonyl)-L-valinyl-D-citrullinamido)benzyl alcohol
Fmoc-Val-Cit-PAB-OH
(9H-fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate
TrastuzumabImpurity2
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide
9H-fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbam
9H-fluoren-9-ylmethyl N-[(2S)-1-[[(2S)-5-(carbamoylamino)-1-[4-(hydroxymethyl)anilino]-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate
Trastuzumab Impurity 2 (Fmoc-Val-Cit-PAB-OH)
Fmoc-L-Val-Cit-PAB-OH
Fomc-Val-Cit-PAB
159858-22-7
159858-22-8
1959858-22-7
ADCs
ADC Linker
ADC-Linker
ADC-Linkers