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HNE

HNE Structure
HNE structure
CAS No.
75899-68-2
Chemical Name:
HNE
Synonyms
4-HNE;4-HYDROXYNONENAL;4-HYDROXY-2-NONENAL;(E)-4-hydroxynon-2-enal;HNE;Ccris 1781;4-hydroxy-2-nonena;(E)-4-HYDROXYNONENAL;(±)4-Hydroxynon-2-enal;HNE ISO 9001：2015 REACH
CBNumber:
CB0281140
Molecular Formula:
C9H16O2
Molecular Weight:
156.22
MDL Number:
MFCD00211020
MOL File:
75899-68-2.mol
Last updated:2025-01-27 09:38:02
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HNE Properties

Boiling point 125-127 °C(Press: 2 Torr)
Density 0.941±0.06 g/cm3(Predicted)
storage temp. -70°C
solubility DMF: >50 mg/ml; DMSO: >50 mg/ml; Ethanol: >50 mg/ml; PBS pH 7.2: >1 mg/ml
pka 13.31±0.20(Predicted)
form Colorless oil.
color Colorless to light yellow
CAS DataBase Reference 75899-68-2(CAS DataBase Reference)
FDA UNII K1CVM13F96
UNSPSC Code 12352114
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P305+P351+P338
NFPA 704
3
0 0

HNE price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 393204 4-Hydroxynonenal-CAS75899-68-2-Calbiochem 4-Hydroxynonenal,CAS75899-68-2,isamajoraldehydeproductformedbyperoxida 75899-68-2 1mg $144 2024-03-01 Buy
Cayman Chemical 32100 4-hydroxy Nonenal ≥98% 75899-68-2 1mg $78 2024-03-01 Buy
Cayman Chemical 32100 4-hydroxy Nonenal ≥98% 75899-68-2 5mg $311 2024-03-01 Buy
Cayman Chemical 32100 4-hydroxy Nonenal ≥98% 75899-68-2 10mg $543 2024-03-01 Buy
Cayman Chemical 32100 4-hydroxy Nonenal ≥98% 75899-68-2 50mg $1912 2022-04-27 Buy
Product number Packaging Price Buy
393204 1mg $144 Buy
32100 1mg $78 Buy
32100 5mg $311 Buy
32100 10mg $543 Buy
32100 50mg $1912 Buy

HNE Chemical Properties,Uses,Production

Uses

4-Hydroxynonenal is an irreversible inhibitor of Na+/K+-ATPase activity.

Uses

HNE is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids such as arachidonic acid. 4-hydroxy Nonenal is widely used as a marker of lipid peroxidation. It exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity. HNE inhibits pro-oxidant-induced Ca2+ release from mitochondria at 10-50 μM.[Cayman Chemical]

Definition

ChEBI: 4-hydroxynon-2-enal is an enal consisting of non-2-ene having an oxo group at the 1-position and a hydroxy group at the 4-position. It has a role as a human metabolite. It is a hydroxyaldehyde, an enal and a 4-hydroxynonenal.

Biological Activity

Primary Target
Na+, K+-ATPase activity', 'Product does not compete with ATP.', 'Target IC50: 120 μM against Na+, K+-ATPase activity

HNE synthesis

693-25-4
75899-68-2
Synthesis of HNE from N-PENTYLMAGNESIUM BROMIDE

HNE Preparation Products And Raw materials

Raw materials

2,3-EPOXYOCTANAL 2-Nonen-4-ol, 1-bromo-, (2E)- 2-Nonenal, 4-[(tetrahydro-2H-pyran-2-yl)oxy]-, (2E)- (E)-4-hydroxynon-2-enal dimethyl acetal Methoxymethylenetriphenylphosphorane
1-Octen-3-ol N-PENTYLMAGNESIUM BROMIDE Acrolein Hexanal 1-Bromopentane

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Preparation Products

4-HYDROXY NONENAL MERCAPTURIC ACID

HNE Suppliers

Global( 121)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19552 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32159 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 22793 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581 sales@chemhifuture.com China 3135 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38630 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054 trendseenbio@gmail.com China 11681 58
Shanghai Acmec Biochemical Technology Co., Ltd. 		+86-18621343501; +undefined18621343501 product@acmec-e.com China 33338 58
Nanjing Bicbiotechnology Co., Ltd 		+86-2552131256 +86-18251840740 sales@bicbiotech.com China 5994 58
Supplier Advantage
BOC Sciences 		58
TargetMol Chemicals Inc. 		58
Dideu Industries Group Limited 		58
InvivoChem 		58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
Nantong HI-FUTURE Biology Co., Ltd. 		58
TargetMol Chemicals Inc. 		58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		58
Shanghai Acmec Biochemical Technology Co., Ltd. 		58
Nanjing Bicbiotechnology Co., Ltd 		58

View Lastest Price from HNE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Hydroxynonenal pictures 2024-11-18 4-Hydroxynonenal
75899-68-2
 US $48.00-171.00 / mg 95.12% 10g TargetMol Chemicals Inc.
4-Hydroxynonenal pictures 2024-11-18 4-Hydroxynonenal
75899-68-2
 US $48.00-171.00 / mg 95.12% 10g TargetMol Chemicals Inc.
HNE pictures 2021-08-12 HNE
75899-68-2
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
  • HNE pictures
  • HNE
    75899-68-2
  • US $15.00-10.00 / KG
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd

75899-68-2(HNE)Related Search:

Titanium tetrachloride Glutathione 4-hydroxy Nonenal-d3 (E)-4-HYDROXY-2-NONENAL,TRANS-4-HYDROXY-2-NONENAL TRANS-4-HYDROXY-2-NONENAL-5,5,6,6,7,7,8,8,9,9,9-D11 DIMETHYL ACETAL
(E)-4-HYDROXYNONENAL-DIMETHYLACETAL,(E)-4-Hydroxynonenal-dimethylacetal, 4-HNE-DMA,(E)-4-Hydroxynonenal-dimethylacetal, 4-HNE-DMA,HNE-DA,HNE-DMA (E)-4-HYDROXYNONENAL, >85% HNE INHIBITOR ANTI-HNE FLUOROPHORE TAC, CD70, CD27 Ligand, Clone: HNE.51, Mab anti-Human, FITC
ANTI-HNE PAB,ANTISERUM TO (E)-4-HYDROXYNONENAL 4-Hydroxynonenal conj. BSA Purified ANTI-(E)-4-HYDROXYNONENAL,ANTI-HNE,ANTI-4-HYDROXY-2-NONENAL 4R-HYDROXY-2-NONENAL ANTI-HNE-MICHAEL ADDUCTS, REDUCED,ANTI-HNE-MICHAEL ADDUCTS, REDUCED (RABBIT),ANTI-HNE-MICHAEL ADDUCTS, REDUCED RABBIT PAB
4S-HYDROXY-2-NONENAL TAC, CD70, CD27 Ligand, Clone: HNE.51, Mab anti-Human HNE (4-Hydroxy-2-nonenal),HNE (4-Hydroxy-2-nonenal)

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Ccris 1781 (E)-4-HYDROXYNONENAL HNE (+/-)-4-HYDROXY-2E-NONENAL (+/-)-4-HYDROXYNON-2-ENAL 4-hydroxy-2-nonena 2-Nonenal, 4-hydroxy-, (2E)- HNE ISO 9001：2015 REACH 4-HYDROXY-2-NONENAL 4-HNE (E)-4-hydroxynon-2-enal 4-HYDROXYNONENAL biomarker,genotoxic,oxidative,Inhibitor,stress,Cancer,Aldehyde Dehydrogenase (ALDH),4-Hydroxynonenal,Endogenous Metabolite,4Hydroxynonenal,nitrosative,mitochondria,4 Hydroxynonenal,inhibit Rabbit Anti-4 Hydroxynonenal antibody Rabbit Anti-4 Hydroxynonenal/PE Conjugated antibody Rabbit Anti-4 Hydroxynonenal/AF647 Conjugated antibody 4-Hydroxynonenal, Lipid peroxidation marker 4-Hydroxynonenal, 10 mM in DMSO (±)4-Hydroxynon-2-enal Mouse 4-Hydroxy-2-nonenal elisa kit 75899-68-2 9001-90-6