Tebufenozide
- CAS No.
- 112410-23-8
- Chemical Name:
- Tebufenozide
- Synonyms
- MIMIC;rh5992;RoMdan;CONFIRM;Conform;MiMic 240LV;MiMic 700WP;ebufenozide;Confirm(TM);TEBUFENOZIDE
- CBNumber:
- CB0286635
- Molecular Formula:
- C22H28N2O2
- Molecular Weight:
- 352.47
- MDL Number:
- MFCD00467963
- MOL File:
- 112410-23-8.mol
- MSDS File:
- SDS
Melting point | 191°; mp 186-188° (Sundaram, 1081) |
---|---|
Density | 1.074±0.06 g/cm3(Predicted) |
vapor pressure | 3 x 10 -6 Pa (25 °C) |
storage temp. | 0-6°C |
solubility | Chloroform: Slightly Soluble,Methanol: Slightly Soluble |
Water Solubility | 0.83 mg l-1 (20 °C) |
pka | 10.89±0.46(Predicted) |
form | Solid |
color | White to off-white |
BRN | 7822297 |
InChI | InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25) |
InChIKey | QYPNKSZPJQQLRK-UHFFFAOYSA-N |
SMILES | C(N(C(C)(C)C)NC(=O)C1=CC=C(CC)C=C1)(=O)C1=CC(C)=CC(C)=C1 |
LogP | 4.240 (est) |
CAS DataBase Reference | 112410-23-8(CAS DataBase Reference) |
EWG's Food Scores | 1 |
FDA UNII | TNN5MI5EKF |
Pesticides Freedom of Information Act (FOIA) | Tebufenozide |
EPA Substance Registry System | Tebufenozide (112410-23-8) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS09 |
---|---|
Signal word | Danger |
Hazard statements | H411 |
Precautionary statements | P273 |
Hazard Codes | N |
Risk Statements | 51/53 |
Safety Statements | 61 |
RIDADR | UN 3077 |
WGK Germany | 2 |
HazardClass | 9 |
PackingGroup | III |
HS Code | 29280000 |
Toxicity | LD50 orally in rats, mice: >5000 mg/kg; dermally in rats: >5000 mg/kg; LD50 in honey bees (96 hr, contact): >234 mg/bee; LC50 in mallard duck (8-day dietary): >5000 mg/kg; LC50 in rainbow trout (96 hr): 5.7 mg/l (Heller) |
Tebufenozide price More Price(8)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 31652 | Tebufenozide PESTANAL | 112410-23-8 | 100mg | $198 | 2024-03-01 | Buy |
Cayman Chemical | 24055 | Tebufenozide ≥95% | 112410-23-8 | 50mg | $90 | 2024-03-01 | Buy |
Cayman Chemical | 24055 | Tebufenozide ≥95% | 112410-23-8 | 100mg | $152 | 2024-03-01 | Buy |
TRC | T013200 | Tebufenozide | 112410-23-8 | 100mg | $135 | 2021-12-16 | Buy |
AK Scientific | G709 | Tebufenozide | 112410-23-8 | 100mg | $154 | 2021-12-16 | Buy |
Tebufenozide Chemical Properties,Uses,Production
General Description
Tebufenozide is an ecdysone insecticide, which causes the premature molting of insects by interfering with the normal development of insects. It has high insecticidal activity and high selectivity, being effective in treatment of all lepidopteran larvae, caterpillar, diamondback moth and beet armyworm. It has a strong ovicidal activity, being safe to non-target organisms. Tebfenozide has no irritating effect on the eyes and skin without any teratogenic, carcinogenic and mutagenic effects on higher animals, being of high safety to mammals, birds and natural enemies. It is an ideal insecticide during integrated control.
Chemical Properties
Pure white powder, melting point 191 ℃. Slightly soluble in water and organic solvents; stable to light. It is stable at 5 ° C in pH 7 aqueous solution upon light emission.
Toxicity (to higher animals)
Low toxicity
Mechanism of Action
Tebufenozide is a pro-skinning compound that selectively controls lepidopteran larvae by acting in close association with the descorticophilin receptor protein. During its effect, tebufenozide mimics the action of natural insect pest hormone 20-hydroxy-descorticoid, leading to its premature, deadly peeling.
Control object and using method
It can be used to control a variety of lettuce larvae such as cabbage, apples and other crops. It is effective in the treatment of all instar larvae at drug interval of 14d.
- Control Spodoptera exigua, Spodoptera litura, Spodoptera frugiperda, melon field borer and cabbage budworm; apply in the early larvae emergence, spray 1 500 ~ 2 000 times 20% SC.
- Control apple leaf roller and peach moth worm, Spray 1000 ~ 2000 times 20% suspension.
- Control corn borer and bean curl moth; spray 1000 ~ 2000 times 20% suspension.
Attention
- This product is toxic to silkworms, should pay attention to be away from the silkworm area.
- This product is generally effective against Plutella xylostella and can be mixed with avermectin.
- Spray uniformly; ensure that the contact of liquid with parasites.
- It is best to apply pesticide in the evening when controlling beet armyworm.
Uses
Synthetic nonsteroidal ecdysone agonist causing premature molting; novel insect growth regulator specific to lepidopteran species. Insecticide.
Uses
Tebufenozide is used to control lepidopterous larvae on rice, fruit, row crops, nut crops, vegetables and vines and in forestry.
Definition
ChEBI: A carbohydrazide that is hydrazine in which the amino hydrogens have been replaced by tert-butyl, 3,5-dimethylbenzoyl and 4-ethylbenzoyl groups respectively. It is an insecticide used widely against caterpillars.
Hazard
Low toxicity by ingestion, inhalation, and skin contact.
Agricultural Uses
Insecticide, Insect growth regulator: Tebufenozide is an insect growth regulator that interferes with molting of Lepidopteran larvae. It is used on fruitworm, fireworms, false armyworm, gypsy moth, and spanworms, and is applied pre-harvest. Registered for use in EU countries. Registered for use in the U.S.
Trade name
CONFIRM®; MIMIC®; RH-5992®
Metabolic pathway
Oxidation of ethyl and methyl substituents of the phenyl rings of tebufenozide occurs in soils and plants, to give carboxylic acids, alcohols and a ketone.
Degradation
Tebufenozide was stable at 94 °C for 7 days, stable to light in pH 7 aqueous solution (25 °C) and stable in dark sterile water for 30 days (25 °C). The DT50 in natural pond water, in light, was 30 days (25 °C) (PM). It was stable in acidic and neutral buffer solutions. Hydrolysis was marked in alkaline conditions (DT50 203 days, pH 10, 20°C). Tebufenozide was stable in sterilised stream water in the dark but degraded in non-sterile water (DT50 181 days). The insecticide was photodegraded by sunlight (DT50 83 hours, summer 46°N). The results suggest that microbial degradation and photolysis will be the main routes of tebufenozide dissipation in natural aquatic conditions (Sundaram, 1994).
Tebufenozide Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Qingdao Trust Agri Chemical Co.,Ltd | +8613573296305 | aroma@qdtrustagri.com | China | 297 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 | peter@yan-xi.com | China | 5873 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 | info@tnjchem.com | China | 2989 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29894 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 15319487004 | 1015@dideu.com | China | 4088 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12450 | 58 |
View Lastest Price from Tebufenozide manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-08-15 | Tebufenozide
112410-23-8
|
US $30.00-10.00 / kg | 1kg | 0.99 | 10 tons | Hebei Yanxi Chemical Co., Ltd. | |
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2024-08-15 | Tebufenozide
112410-23-8
|
US $0.00 / kg | 1kg | 99 | 20tons | qingdao trust agri chemical co.,ltd | |
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2023-09-06 | Tebufenozide
112410-23-8
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Guanlang Biotechnology Co., Ltd. |
-
- Tebufenozide
112410-23-8
- US $30.00-10.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
-
- Tebufenozide
112410-23-8
- US $0.00 / kg
- 99
- qingdao trust agri chemical co.,ltd
-
- Tebufenozide
112410-23-8
- US $0.00-0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.