PRKMK1
- CAS No.
- Chemical Name:
- PRKMK1
- Synonyms
- MKK1;MAPKK1;MAP2K1;PRKMK1;MEK1 active;MAPK/ERK kinase 1;MAP Kinase Kinase 1 human;MEK1, active, GST tagged human;MEK1 (EE), active, GST tagged from mouse;Mitogen-activated protein kinase kinase 1
- CBNumber:
- CB02886886
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00239713
- MOL File:
- Mol file
PRKMK1 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M8822 | MEK1, active, GST tagged human PRECISIO? Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution | 10μG | $500 | 2023-06-20 | Buy | |
| Usbiological | 026845 | Mitogen Activated Protein Kinase Kinase 1 | 96Tests | $864 | 2021-12-16 | Buy | |
| Usbiological | 366318 | Mitogen Activated Protein Kinase Kinase 1 | 96Tests | $911 | 2021-12-16 | Buy |
PRKMK1 Chemical Properties,Uses,Production
Uses
MEK1, active, GST tagged human has been used to induce kinase reactions in in vitro mitogen activated protein kinase/ERK kinase (MEK)1 kinase assay. It has also been used to activate extracellular-signal-regulated kinase 2 (ERK2) by phosphorylation.
General Description
Mitogen activated protein kinase/ERK kinase (MEK)1 is a hydrophilic non-receptor protein and is a member of dual specificity protein kinase family. It is ubiquitously expressed. MAP2K1 is encoded by the gene mapped to human chromosome 15q22.31.
Biochem/physiol Actions
Mitogen activated protein kinase/ERK kinase (MEK)1/2 catalyzes the phosphorylation of tyrosine and then threonine in extracellular-signal-regulated kinase1/2. As an essential component of RAS?RAF?MEK?ERK signaling pathway (MAP kinase signaling cascade), it is involved in the regulation of apoptosis, cell cycle progression, cell migration, differentiation, metabolism, and proliferation. Constitutive activation of MEK1 results in cellular transformation. Thus, MEK1 represents a likely target for pharmacologic intervention in proliferative diseases such as cancer.
PRKMK1 Preparation Products And Raw materials
Raw materials
Preparation Products
PRKMK1 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Aibotek Biotechnology Co., Ltd. | -- | tech@abclonal.com | CHINA | 6796 | 58 |
| Suzhou Ruinuode Biotechnology Co., Ltd. | -- | 2090855807@qq.com | CHINA | 6063 | 58 |
| Shanghai Qunji Biological Technology Co., Ltd. | -- | CHINA | 6971 | 58 | |
| Nanjing Sai Ruirui Biotechnology Co., Ltd. | -- | sales@shrbio.com | CHINA | 6873 | 58 |
| Annuol (Beijing) Biotechnology Co., Ltd. | -- | inquiry@annoron.com | CHINA | 6434 | 58 |
| Baiao De Biotechnology Co., Ltd. | -- | nanjing@biogot.com | CHINA | 1495 | 58 |
| Shanghai Jingke Chemical Technology Co., Ltd. | -- | jingkehuaxue@163.com | CHINA | 6974 | 58 |
| Beijing Bi Orange Blue Biotechnology Co., Ltd. | -- | bo49855987@163.com | CHINA | 6827 | 58 |
| Beijing Fubo Biotechnology Co., Ltd. | -- | info@f-biology.com | CHINA | 6039 | 58 |
| Shanghai Beinuo Biotechnology Co., Ltd. | -- | beinuobio@163.com | CHINA | 6580 | 58 |