PRKMK1

PRKMK1 C화학적 특성, 용도, 생산

용도

MEK1, active, GST tagged human has been used to induce kinase reactions in in vitro mitogen activated protein kinase/ERK kinase (MEK)1 kinase assay. It has also been used to activate extracellular-signal-regulated kinase 2 (ERK2) by phosphorylation.

일반 설명

Mitogen activated protein kinase/ERK kinase (MEK)1 is a hydrophilic non-receptor protein and is a member of dual specificity protein kinase family. It is ubiquitously expressed. MAP2K1 is encoded by the gene mapped to human chromosome 15q22.31.

Biochem/physiol Actions

Mitogen activated protein kinase/ERK kinase (MEK)1/2 catalyzes the phosphorylation of tyrosine and then threonine in extracellular-signal-regulated kinase1/2. As an essential component of RAS?RAF?MEK?ERK signaling pathway (MAP kinase signaling cascade), it is involved in the regulation of apoptosis, cell cycle progression, cell migration, differentiation, metabolism, and proliferation. Constitutive activation of MEK1 results in cellular transformation. Thus, MEK1 represents a likely target for pharmacologic intervention in proliferative diseases such as cancer.

PRKMK1 준비 용품 및 원자재

원자재

준비 용품

PRKMK1 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Wuhan Aibotek Biotechnology Co., Ltd.	--	tech@abclonal.com	CHINA	6796	58
Suzhou Ruinuode Biotechnology Co., Ltd.	--	2090855807@qq.com	CHINA	6063	58
Shanghai Qunji Biological Technology Co., Ltd.	--		CHINA	6971	58
Nanjing Sai Ruirui Biotechnology Co., Ltd.	--	sales@shrbio.com	CHINA	6873	58
Annuol (Beijing) Biotechnology Co., Ltd.	--	inquiry@annoron.com	CHINA	6434	58
Baiao De Biotechnology Co., Ltd.	--	nanjing@biogot.com	CHINA	1495	58
Shanghai Jingke Chemical Technology Co., Ltd.	--	jingkehuaxue@163.com	CHINA	6974	58
Beijing Bi Orange Blue Biotechnology Co., Ltd.	--	bo49855987@163.com	CHINA	6827	58
Beijing Fubo Biotechnology Co., Ltd.	--	info@f-biology.com	CHINA	6039	58
Shanghai Beinuo Biotechnology Co., Ltd.	--	beinuobio@163.com	CHINA	6580	58