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ROSOLIC ACID

CAS No.
603-45-2
Chemical Name:
ROSOLIC ACID
Synonyms
AURIN;RosoL;AURINE;CORALLIN;CI 43800;AURIN GR;Nsc 7805;Aurin 555;Rosolic aci;CI NO 43800
CBNumber:
CB0296269
Molecular Formula:
C19H14O3
Molecular Weight:
290.31
MDL Number:
MFCD00001624
MOL File:
603-45-2.mol
MSDS File:
SDS
Last updated:2024-12-18 13:37:16

ROSOLIC ACID Properties

Melting point 309°C (decompose)
Boiling point 372.4°C (rough estimate)
Density 1.2497 (rough estimate)
refractive index 1.4200 (estimate)
storage temp. Store at room temperature.
solubility Practically insoluble in water, benzene; freely soluble in ethanol
form Crystalline Powder
Colour Index 43800
pka 6.98(at 25℃)
color Red-brown to brownish-red
PH Range 6.8(YELLOW)--8.2(RED)
Water Solubility Soluble in alcohol, sodium hydroxide, potassium hydroxide and strong acids. Insoluble in water.
λmax 534.6nm, 479.5nm, 482nm
Merck 14,881
BRN 2055205
Stability Stable. Incompatible with strong oxidizing agents.
Major Application electrorheological materials, films patterning, antireflective coatings, thermochromic materials, photoresists, film patterning, recording materials, lithium battery, semiconductors, printing materials, inks, corrosion inhibitors, adhesives, drugs, detecting viable cells, treatment of Alzheimer’s disease
CAS DataBase Reference 603-45-2
EWG's Food Scores 1
FDA UNII 85N4AK3JAU
EPA Substance Registry System 2,5-Cyclohexadien-1-one, 4-[bis(4-hydroxyphenyl)methylene]- (603-45-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  Xi
Risk Statements  36/37/38-36/38
Safety Statements  26-36-37/39
WGK Germany  3
TSCA  Yes
HS Code  29145090
NFPA 704
1
2 0

ROSOLIC ACID price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 861324 p-Rosolic acid Dye content 85% 603-45-2 25g $129 2024-03-01 Buy
Sigma-Aldrich 861324 p-Rosolic acid Dye content 85% 603-45-2 100g $447 2024-03-01 Buy
Sigma-Aldrich RX0175 Rosolic Acid 603-45-2 25g $143 2023-01-07 Buy
TCI Chemical A0598 Pararosolic Acid 603-45-2 25g $65 2024-03-01 Buy
Alfa Aesar B21737 Rosolic acid 603-45-2 25g $79.4 2024-03-01 Buy
Product number Packaging Price Buy
861324 25g $129 Buy
861324 100g $447 Buy
RX0175 25g $143 Buy
A0598 25g $65 Buy
B21737 25g $79.4 Buy

ROSOLIC ACID Chemical Properties,Uses,Production

Chemical Properties

red crystals or powder

Uses

A red coloring medium made from phenol or carbolic acid. It is soluble in alcohol and ether but insoluble in water. When fabrics were steeped in this solution, the color was nonactinic and therefore safe for darkrooms, windows, and doorways. Aurin was also mixed with water-soluble gums and brushed on the backs of collodion and silver bromide gelatin plates as an antihalation layer.

Uses

activates heme oxygenase, anti-oxidative stress, inhibits DNA fragmentation

Uses

Rosolic acid is used as a pH indicator in the range from 5.0 to 6.8. It acts as an intermediate in the manufacturing dyes. It is involved in the activation of heme oxygenase and in the inhibition of DNA fragmentation. It finds application in the selective isolation of coliform bacteria.

Definition

ChEBI: Aurin is a diarylmethane.

Purification Methods

It forms green crystals with a metallic luster, but the colour depends on the solvent used. When recrystallised from brine (saturated aqueous NaCl) acidified with HCl, it forms red needles, but when recrystallised from EtO/AcOH, the crystals have a beetle iridescent green colour. It has been recrystallised from Me2CO (although it dissolves slowly), methyl ethyl ketone, 80-95% AcOH and from AcOH/*C6H6. An aqueous KOH solution is golden yellow, and a 70% H2SO4 solution is deep red in colour. An alternative purification is to dissolve this triphenylmethane dye in 1.5% of aqueous NH3, filter, and heat to 70-80o, then acidify with dilute AcOH by adding it slowly with vigorous stirring, whereby the aurin separates as a brick-red powder or as purplish crystals depending on the temperature and period of heating. Filter off the solid, wash it with H2O and a little dilute AcOH, then H2O again. Stir this solid with Et2O to remove any ketones and allow it to stand overnight in the Et2O, then filter and dry it in air then in a vacuum. [Gomberg & Snow J Am Chem Soc 47 202 1925, Baines & Driver J Chem Soc 123 1216 1923, UV: Burawoy Chem Ber 64 462 1941, Beilstein 8 IV 2646.]

56-23-5
108-95-2
456-55-3
603-45-2
Synthesis of ROSOLIC ACID from Carbon tetrachloride and Phenol
Global( 234)Suppliers
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Henan Tianfu Chemical Co.,Ltd.
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LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43340 58

View Lastest Price from ROSOLIC ACID manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Rosolic Acid pictures 2024-10-28 Rosolic Acid
603-45-2
US $1520.00-1980.00 / mg 10g TargetMol Chemicals Inc.
Pararosolic Acid pictures 2021-07-02 Pararosolic Acid
603-45-2
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
Aurin pictures 2019-07-06 Aurin
603-45-2
US $1.00 / kg 1kg 95%-99% 1000kg Career Henan Chemical Co
  • Rosolic Acid pictures
  • Rosolic Acid
    603-45-2
  • US $1520.00-1980.00 / mg
  • TargetMol Chemicals Inc.
  • Pararosolic Acid pictures
  • Pararosolic Acid
    603-45-2
  • US $15.00-10.00 / KG
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd
  • Aurin pictures
  • Aurin
    603-45-2
  • US $1.00 / kg
  • 95%-99%
  • Career Henan Chemical Co
4-[Bis(4-hydroxyphenyl)methylene]-2,5-cyclohexadienone, Aurin 4,4'-Dihydroxyfuchsone Corallin Spirit Soluble Spirit Aurin Rosolic acid (CI x 43800) 4-(p,p′-Dihydroxybenzhydrylidine)-2,5-cyclohexadien-1-one Corallin Aurin p-Rosolic Acid Rosolic aci 4-(bis(4-hydroxyphenyl)Methylene)cyclohexa-2,5-dienone PARAROSOLIC ACID P-ROSOLIC ACID 4-[bis(4-hydroxyphenyl)methylene]-5-cyclohexadien-1-one CORALLIN CORALLIN RED CORALLIN YELLOW CI NO 43800 CI 43800 LABOTEST-BB LT00847601 AURIN AURINE 4-(Bis(4-hydroxyphenyl) cyclohexa-2,5-dienone 4-[BIS(4-HYDROXYPHENYL)METHYLENE]-2,5-CYCLOHEXADIEN-1-ONE 4-[BIS(4-HYDROXYPHENYL)METHYLENE]-2,5-CYCLOHEXADIENONE 4-[BIS-(P-HYDROXYPHENYL)METHYLENE]-2,5-CYCLO-HEXADIEN-1-ONE ROSOLIC ACID INDICATOR ROSOLIC ACID (C.I. 43800) ROSOLIC ACID PRACTICAL GRADE ROSOLIC ACID C.I. 43800 INDICATOR FOR MICROSCOPY AURIN FOR MICROSCOPY (Rosolic Acid) C.I. No 43800 Para-ROSOLIC ACID INDICATOR AURIN (C.I. 43800) 4-[bis(p-hydroxyphenyl)methylene]cyclohexa-2,5-dien-1-one Roseolic acid AURIN GR RHODIZONIC ACID Dihydrate(P) 2,5-cyclohexadien-1-one, 4-[bis(p-hydroxyphenyl)methylene]- 4-(p,p′-dihydroxybenzhydrylidene)-2,5-cyclohexadien-1-one 4-[bis(p-hydroxy- Aphenyl)methylene]-2,5-cyclohexadien-1-one Aurin 555 Nsc 7805 Rosalic Acid Spirit Aurine 2,5-Cyclohexadien-1-one, 4-bis(4-hydroxyphenyl)methylene- Aurine、Pararosolic acid p-Rosolic acid, indicator Aurin (p-rosolic acid) RosoL 4-[bis(4-hydroxyphenyl)methylidene]cyclohexa-2,5-dien-1-one Rosolic acid pH indicator solution ROSOLIC ACID USP/EP/BP Rosonic acid, indicator TIANFUCHEM--High purity ROSOLIC ACID factory price p-ROSOLIC ACID INDICATOR For Microscopy 4-(Bis(4-hydroxyphenyl)methylene)cyclohexa-2,5-dien-1-one AURIN (p-ROSALIC ACID) Aurin (P-Rosolic Acid) For Microscopy 603-45-2