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Bromo-PEG4-t-butyl ester

Bromo-PEG4-t-butyl ester structure

CAS No.: 564476-32-0

Chemical Name:: Bromo-PEG4-t-butyl ester

Synonyms: Br-PEG4-C2-Boc;Br-PEG4-COOtBu;CAS_564476-32-0;Br-PEG4-CH2CH2COOtBu;Br-PEG4-t-butyl ester;Bromo-PEG5-t-butyl ester;Bromo-PEG4-t-butyl ester;tert-butyl 3-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]propanoate;4,7,10,13-Tetraoxapentadecanoic acid, 15-bromo-, 1,1-dimethylethyl ester;3,6,9,12-Tetraoxapentadecan-15-oic acid, 1-bromo-, 1,1-dimethylethylester

CBNumber:: CB03048720

Molecular Formula:: C15H29BrO6

Molecular Weight:: 385.29

MDL Number:: MFCD22574808

MOL File:: 564476-32-0.mol

MSDS File:: SDS

Last updated:2025-04-17 18:22:24

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Bromo-PEG4-t-butyl ester Properties

Boiling point	415.8±35.0 °C(Predicted)
Density	1.210±0.06 g/cm3(Predicted)
solubility	Soluble in DMSO, DCM, DMF
form	Liquid
color	Colorless to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P280-P301+P312-P302+P352-P305+P351+P338

Bromo-PEG4-t-butyl ester price More Price(13)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0107159	Br-PEG4-C2-Boc	564476-32-0	50mg	$90	2021-12-16	Buy
BroadPharm	BP-20711	Bromo-PEG4-t-butylester 98%	564476-32-0	500mg	$140	2021-12-16	Buy
ChemScene	CS-0107159	Br-PEG4-C2-Boc	564476-32-0	100mg	$150	2021-12-16	Buy
ChemScene	CS-0107159	Br-PEG4-C2-Boc	564476-32-0	250mg	$200	2021-12-16	Buy
AK Scientific	2640CT	Bromo-PEG4-t-butylester	564476-32-0	100mg	$522	2021-12-16	Buy

Product number	Packaging	Price	Buy
CS-0107159	50mg	$90	Buy
BP-20711	500mg	$140	Buy
CS-0107159	100mg	$150	Buy
CS-0107159	250mg	$200	Buy
2640CT	100mg	$522	Buy

Bromo-PEG4-t-butyl ester Chemical Properties,Uses,Production

Description

Bromo-PEG4-t-butyl ester is a PEG linker containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

Br-PEG4-C2-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Biological Activity

Br-PEG4-C2-Boc is a cleavable ADC linker containing 4 units of PEG, which can be used to synthesize antibody drug conjugates (ADC).

target

Cleavable

PEGs

Alkyl/ether

IC 50

Cleavable Linker; PEGs; Alkyl/ether

References

[1] Robert Yongxin Zhao, et al. Cytotoxic agents. WO2003068144A2.

Bromo-PEG4-t-butyl ester synthesis

Synthesis of Bromo-PEG4-t-butyl ester from Tos-PEG5 t-butyl ester

Bromo-PEG4-t-butyl ester Preparation Products And Raw materials

Raw materials

Tos-PEG5 t-butyl ester Hydroxy-PEG4-t-butyl ester tert-Butyl acrylate Carbon tetrabromide Bis[2-(2-hydroxyethoxy)ethyl] ether

Preparation Products

Bromo-PEG4-t-butyl ester Suppliers

Global( 71)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shaanxi Dideu Medichem Co. Ltd	+86-29-87569266 15319487004	1015@dideu.com	China	3978	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	contact@trustwe.com	China	5738	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32159	58
Wuhan Borenpharm Co., Ltd	027-65563561 18717150066	3207347307@qq.com	CHINA	1238	58
Hangzhou Huarong Pharm Co., Ltd.	571-86758373 +8613588754946	sales@huarongpharm.com	CHINA	3148	58
ChemExpress	+86-021-58950125 +86-021-58950125;	info@chemexpress.com	China	782	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38630	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8467	58
Jilin Chinese Academy of Sciences-yanshen Technology	+undefined18143011203	info@chemextension.com	China	42056	58
Xian confluore Biological Technology Co., Ltd.	+86-15680926068 +86-15680926068	1924344760@confluore.cn	China	2996	58

Supplier	Advantage
Shaanxi Dideu Medichem Co. Ltd	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
TargetMol Chemicals Inc.	58
Wuhan Borenpharm Co., Ltd	58
Hangzhou Huarong Pharm Co., Ltd.	58
ChemExpress	58
TargetMol Chemicals Inc.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Jilin Chinese Academy of Sciences-yanshen Technology	58
Xian confluore Biological Technology Co., Ltd.	58

View Lastest Price from Bromo-PEG4-t-butyl ester manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-10-28	Br-PEG4-C2-Boc 564476-32-0	US $0.00 / mg			10g	TargetMol Chemicals Inc.
	2024-03-25	Br-PEG4-COOtBu 564476-32-0	US $0.00 / g	5g	>98.00%	5g	Xian confluore Biological Technology Co., Ltd.

Br-PEG4-C2-Boc
564476-32-0
US $0.00 / mg
TargetMol Chemicals Inc.

Br-PEG4-COOtBu
564476-32-0
US $0.00 / g
>98.00%
Xian confluore Biological Technology Co., Ltd.

564476-32-0(Bromo-PEG4-t-butyl ester)Related Search:

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Bromo-PEG4-t-butyl ester Bromo-PEG5-t-butyl ester Br-PEG4-t-butyl ester CAS_564476-32-0 Br-PEG4-CH2CH2COOtBu Br-PEG4-COOtBu Br-PEG4-C2-Boc 4,7,10,13-Tetraoxapentadecanoic acid, 15-bromo-, 1,1-dimethylethyl ester 3,6,9,12-Tetraoxapentadecan-15-oic acid, 1-bromo-, 1,1-dimethylethylester Br-PEG4-CH2CH2COOtBu/4,7,10,13-Tetraoxapentadecanoic acid, 15-bromo-, 1,1-dimethylethyl ester tert-butyl 3-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]propanoate 564476-32-0 C15H29BrO6