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(2S)-OMPT

(2S)-OMPT Structure
(2S)-OMPT structure
CAS No.
1217471-69-6
Chemical Name:
(2S)-OMPT
Synonyms
(2S)-OMPT (triethylamine);SHELRVLEXVWOAY-JNYXYQEXSA-N
CBNumber:
CB03152922
Molecular Formula:
C34H73N2O6PS
Molecular Weight:
668.992
MDL Number:
MOL File:
1217471-69-6.mol
Last updated:2023-04-10 09:29:42
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(2S)-OMPT Properties

solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml

(2S)-OMPT price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10005707 (2S)-OMPT ≥98% 1217471-69-6 500μg $71 2024-03-01 Buy
Cayman Chemical 10005707 (2S)-OMPT ≥98% 1217471-69-6 1mg $133 2024-03-01 Buy
Cayman Chemical 10005707 (2S)-OMPT ≥98% 1217471-69-6 5mg $554 2024-03-01 Buy
Cayman Chemical 10005707 (2S)-OMPT ≥98% 1217471-69-6 10mg $968 2024-03-01 Buy
Product number Packaging Price Buy
10005707 500μg $71 Buy
10005707 1mg $133 Buy
10005707 5mg $554 Buy
10005707 10mg $968 Buy

(2S)-OMPT Chemical Properties,Uses,Production

Description

Lysophosphatidic acid (LPA) is a potent lipid mediator that elicits its effect through four distinct receptors - LPA1/EDG-2, LPA2/EDG-4, LPA3/EDG-7 and LPA4/GPR23.1,2 OMPT is a selective agonist of the lysophosphatidic acid 3 (LPA3) receptor. It exhibits EC50 values of 68 nM and >6.8 μM for calcium mobilization in LPA1 and LPA2-expressing Sf9 cells, respectively.3 The (2S)-OMPT enantiomer is 5- to 20-fold more active than (2R)-OMPT in calcium release assays in both LPA3-transfected Sf9 and rat hepatoma Rh7777 cells.4

References

1. Chun, J., Goetzl, E.J., Hla, T., et al. International union of pharmacology. XXXIV. Lysophospholipid receptor nomenclature Pharmacol. Rev. 54,265-269(2002).
2. Niu, S.L., Mitchell, D.C., and Litman, B.J. Trans fatty acid derived phospholipids show increased membrane cholesterol and reduced receptor activation as compared to their cis analogs Biochemistry 44,4458-4465(2005).
3. Hasegawa, Y., Erickson, J.R., Goddard, G.J., et al. Identification of a phosphothionate analogue of lysophosphatidic acid (LPA) as a selective agonist of the LPA3 receptor J. Biol. Chem. 278(14),11962-11969(2003).
4. Qian, L., Xu, Y., Hasegawa, Y., et al. Enantioselective responses to a phosphorothioate analogue of lysophosphatidic acid with LPA3 receptor-selective agonist activity J. Med. Chem. 46,5575-5578(2003).

(2S)-OMPT Preparation Products And Raw materials

Raw materials

Preparation Products

(2S)-OMPT Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11975 58
Supplier Advantage
Shanghai Hongye Biotechnology Co. Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
MedBioPharmaceutical Technology Inc 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
SHELRVLEXVWOAY-JNYXYQEXSA-N (2S)-OMPT (triethylamine) 1217471-69-6