ChemicalBook >> CAS DataBase List >>HO-PEG8-CH2COOH
HO-PEG8-CH2COOH
- CAS No.
- 780006-30-6
- Chemical Name:
- HO-PEG8-CH2COOH
- Synonyms
- HO-PEG8-CH2COOH;Hydroxy-PEG8-acetic acid;Acetic acid, 2-[(23-hydroxy-3,6,9,12,15,18,21-heptaoxatricos-1-yl)oxy]-;HO-PEG8-CH2COOH/Acetic acid, 2-[(23-hydroxy-3,6,9,12,15,18,21-heptaoxatricos-1-yl)oxy]-
- CBNumber:
- CB03309429
- Molecular Formula:
- C18H36O11
- Molecular Weight:
- 428.47
- MDL Number:
- MFCD31656912
- MOL File:
- 780006-30-6.mol
Last updated:2023-02-23 14:24:01
HO-PEG8-CH2COOH Chemical Properties,Uses,Production
Biological Activity
HO-PEG8-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
HO-PEG8-CH2COOH Preparation Products And Raw materials
Raw materials
Preparation Products
HO-PEG8-CH2COOH Suppliers
Global( 12)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
9i LLC | +18039569191 | MWan@NiNeiLab.com | United States | 418 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
Amatek Scientific Co. Ltd. | 0512-56316828 | info@amateksci.com | China | 28819 | 58 |
Guangzhou Hongyuan Chemical Co.,Ltd | 15817493340 | 981810490@qq.com | China | 1566 | 58 |
Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29778 | 58 |
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80514535 19917294565 | et@chemextension.com | China | 5061 | 58 |
Shanghai Haohong Scientific Co., Ltd. | 400-400-8210725 | malulu@leyan.com | China | 40041 | 58 |
Chengdu Hanwei Biotechnology Co., Ltd | 17360178904 18217049878 | zengzongwen@pegtide.com | China | 1222 | 58 |
Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | ET-market@chemextension.com | China | 41846 | 58 |
HO-PEG8-CH2COOH
HO-PEG8-CH2COOH/Acetic acid, 2-[(23-hydroxy-3,6,9,12,15,18,21-heptaoxatricos-1-yl)oxy]-
Acetic acid, 2-[(23-hydroxy-3,6,9,12,15,18,21-heptaoxatricos-1-yl)oxy]-
Hydroxy-PEG8-acetic acid
780006-30-6