Sulbactam sodium
- CAS No.
- 69388-84-7
- Chemical Name:
- Sulbactam sodium
- Synonyms
- Sodium Sodium;Sulbatam Sodium;SODIUM SULBACTAM;Sterile Sulbactam sodium;(2S,5R);CP-45899-2;Shu ba sodium;sulbacyam sodium;SULBACTAM SODIUM;cp45899sodiumsalt
- CBNumber:
- CB0370356
- Molecular Formula:
- C8H12NNaO5S
- Molecular Weight:
- 257.24
- MDL Number:
- MFCD01750374
- MOL File:
- 69388-84-7.mol
- MSDS File:
- SDS
Melting point | >230°C (dec.) |
---|---|
storage temp. | -20°C Freezer, Under Inert Atmosphere |
solubility | Freely soluble in water, sparingly soluble in ethyl acetate, very slightly soluble in ethanol (96 per cent). It is freely soluble in dilute acids. |
form | Solid |
color | White |
InChIKey | NKZMPZCWBSWAOX-IBTYICNHSA-M |
CAS DataBase Reference | 69388-84-7(CAS DataBase Reference) |
FDA UNII | DKQ4T82YE6 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 |
Hazard Codes | Xn |
Risk Statements | 42/43 |
Safety Statements | 22-24-36/37-45-24/25 |
HS Code | 29349990 |
Toxicity | LD50 ivn-rat: 6500 mg/kg NKRZAZ 32(Suppl 4),97,84 |
Sulbactam sodium price More Price(27)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | Y0000529 | Sulbactam sodium European Pharmacopoeia (EP) Reference Standard | 69388-84-7 | y0000529 | $220 | 2024-03-01 | Buy |
TRC | S699185 | SulbactamSodiumSalt | 69388-84-7 | 2g | $180 | 2021-12-16 | Buy |
TRC | S699185 | SulbactamSodiumSalt | 69388-84-7 | 50mg | $65 | 2021-12-16 | Buy |
Axon Medchem | Axon2041 | Sulbactamsodium-CP45899sodium 98% | 69388-84-7 | 25mg | $77 | 2021-12-16 | Buy |
Apolloscientific | BIS0150 | Sulbactam sodium | 69388-84-7 | 1g | $95 | 2021-12-16 | Buy |
Sulbactam sodium Chemical Properties,Uses,Production
Description
Sulbactam sodium is a parenterally-active, β-lactamase inhibitor recently introduced as a 1: 1 combination product with cefoperazone. Like clavulanic acid, the first agent of this type to b e introduced, sulbactam enhances the effectiveness of β-lactam antibiotics against resistant strains.
Chemical Properties
White Solid
Originator
Pfizer (USA)
Uses
A semi-synthetic β-lactamase inhibitor. It is used in combination with β-lactam antibiotics as antibacterial.
Definition
ChEBI: Sulbactam sodium is an organooxygen compound and an organonitrogen compound. It is functionally related to an alpha-amino acid.
Manufacturing Process
Sulbactam sodium is semi-synthetic antibiotic of penicillinic group. Start
material for it's synthesis is 6-aminopenicillanic acid. First 6-aminopenicillanic
acid was isolated in 1957 year from benzylpenicilline as resalt of treating of it
by penicillinaze. Benzylpenicilline is produced by microorganism of genus
Streptomyces.
Further, 6-aminopenicillanic acid reacted with bromine, hydrochloric acid and
NaNO2. As a result the 6,6-dibromopenicillanic acid was obtained.
6,6-Dibromopenicillanic acid was oxidized by KMnO4, to give 6,6-dibromo-1,1-The 6,6-dibromo-1,1-dioxopenicillanic acid in presence of Fe was converted to
the 1,1-dioxopenicillanic acid (sulbactam acid). The sulbactam acid was
treated by sodium 2-ethylhexanoate and crude sulbactam sodium was
obtained.
brand name
SULPERAZONE
Therapeutic Function
Beta-lactamase inhibitor
General Description
Sulbactam was synthesized by Pfizer Research Laboratories in 1977 in the course of screening for β-lactamase inhibitors. It shows strong activity against penicillinase and moderate activity against cephalosporinase. Sulbactam itself shows activity against some gramnegative bacteria but no activity against most pathogenic bacteria. The use of sulbactam in combination with cefoperazone, which is partially hydrolyzed by penicillinase, is under study along with its use as an esterified complex with ampicillin (sultamicillin) for therapy of cefoperazone-ampicillin-resistant infections.
Safety Profile
Poison by intravenous route. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and SOx
Sulbactam sodium Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8811 | 58 |
Hebei Yime New Material Technology Co., Ltd. | +86-66697723 +86-17703311139 | admin@china-yime.com | China | 563 | 58 |
Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | info@fortunachem.com | China | 5978 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5892 | 58 |
Sinoway Industrial co., ltd. | 0592-5800732; +8613806035118 | xie@china-sinoway.com | China | 988 | 58 |
Hebei Weibang Biotechnology Co., Ltd | +8617732866630 | bess@weibangbio.com | China | 18153 | 58 |
shandong perfect biotechnology co.ltd | +86-53169958659 +86-13153181156 | sales@sdperfect.com | China | 294 | 58 |
Hangzhou ICH Biofarm Co., Ltd | +86-0571-28186870; +undefined8613073685410 | sales@ichemie.com | China | 998 | 58 |
Hangzhou Hyper Chemicals Limited | +86-0086-57187702781 +8613675893055 | info@hyper-chem.com | China | 295 | 58 |
Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618092446649 | sarah@tnjone.com | China | 1143 | 58 |
View Lastest Price from Sulbactam sodium manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-25 | Sulbactam sodium
69388-84-7
|
US $0.00-0.00 / kg | 1kg | 99% | 20tons | Sinoway Industrial co., ltd. | ||
2024-11-22 | Sulbactam sodium
69388-84-7
|
US $0.00 / KG/Tin | 10KG | 98%min, sterile or non-sterile, USP | 500kg | WUHAN FORTUNA CHEMICAL CO., LTD | ||
2024-11-19 | Sulbactam sodium
69388-84-7
|
US $44.00-31.00 / mg | 99.63% | 10g | TargetMol Chemicals Inc. |
- Sulbactam sodium
69388-84-7
- US $0.00-0.00 / kg
- 99%
- Sinoway Industrial co., ltd.
- Sulbactam sodium
69388-84-7
- US $0.00 / KG/Tin
- 98%min, sterile or non-sterile, USP
- WUHAN FORTUNA CHEMICAL CO., LTD
- Sulbactam sodium
69388-84-7
- US $44.00-31.00 / mg
- 99.63%
- TargetMol Chemicals Inc.