ChemicalBook > Product Catalog >API >Antibiotics >β-Lactamase inhibitors >Sulbactam sodium

Sulbactam sodium

Sulbactam sodium Suppliers list
Company Name: Hebei Weibang Biotechnology Co., Ltd
Tel: +8615531157085
Email: abby@weibangbio.com
Products Intro: Product Name:Sulbactam sodium
CAS:69388-84-7
Purity:99% Package:25KG;0.00;USD
Company Name: Hebei Yime New Material Technology Co., Ltd.
Tel: +86-66697723 +86-17703311139
Email: admin@china-yime.com
Products Intro: Product Name:Sulbactam sodium
CAS:69388-84-7
Purity:99% Package:1KG;20USD
Company Name: Wuhan Fortuna Chemical Co., Ltd
Tel: +86-027-59207850
Email: info@fortunachem.com
Products Intro: Product Name:Sulbactam sodium
CAS:69388-84-7
Purity:98%min, sterile or non-sterile, USP Package:10KG/Tin;USD
Company Name: Hebei Chuanghai Biotechnology Co,.LTD
Tel: +86-13131129325
Email: sales1@chuanghaibio.com
Products Intro: Product Name:sulbactam sodium
CAS:69388-84-7
Purity: 99% Package:1KG;1.90;USD
Company Name: Sinoway Industrial co., ltd.
Tel: 0592-5800732; +8613806035118
Email: xie@china-sinoway.com
Products Intro: Product Name:Sulbactam sodium
CAS:69388-84-7
Purity:99% Package:1kg;|25kg;|100kg

Sulbactam sodium manufacturers

  • Sulbactam sodium
  • Sulbactam sodium pictures
  • $0.00 / 1kg
  • 2024-12-25
  • CAS:69388-84-7
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 20tons
  • Sulbactam Sodium
  • Sulbactam Sodium pictures
  • $150.00 / 1kg
  • 2024-12-25
  • CAS:69388-84-7
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 500kg
  • Sulbactam sodium
  • Sulbactam sodium pictures
  • $0.00 / 10KG/Tin
  • 2024-12-13
  • CAS:69388-84-7
  • Min. Order: 10KG
  • Purity: 98%min, sterile or non-sterile, USP
  • Supply Ability: 500kg
Sulbactam sodium Basic information
Product Name:Sulbactam sodium
Synonyms:SULBACTAM SODIUM;SULBACTAM SODIUM SALT;sodium (2s-cis)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide;4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3,3-dimethyl-7-oxo-, 4,4-dioxide, sodium salt, (2S,5R)- (9CI);(2S-cis)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3,2,0]heptane-2-carboxylic acid 4,4-dioxide sodium salt;sodium (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide;sulbacyam sodium;AMPICILLIN SODIUM AND SULBACTAM SODIUM 2:1
CAS:69388-84-7
MF:C8H12NNaO5S
MW:257.24
EINECS:273-984-4
Product Categories:pharmaceutical raw material;Antibiotic;Pharmaceutical raw materials;Inhibitors;Pharma;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;API;APIs;69388-84-7
Mol File:69388-84-7.mol
Sulbactam sodium Structure
Sulbactam sodium Chemical Properties
Melting point >230°C (dec.)
storage temp. -20°C Freezer, Under Inert Atmosphere
solubility Freely soluble in water, sparingly soluble in ethyl acetate, very slightly soluble in ethanol (96 per cent). It is freely soluble in dilute acids.
form Solid
color White
InChIKeyNKZMPZCWBSWAOX-IBTYICNHSA-M
CAS DataBase Reference69388-84-7(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 42/43
Safety Statements 22-24-36/37-45-24/25
HS Code 29349990
ToxicityLD50 ivn-rat: 6500 mg/kg NKRZAZ 32(Suppl 4),97,84
MSDS Information
Sulbactam sodium Usage And Synthesis
DescriptionSulbactam sodium is a parenterally-active, β-lactamase inhibitor recently introduced as a 1: 1 combination product with cefoperazone. Like clavulanic acid, the first agent of this type to b e introduced, sulbactam enhances the effectiveness of β-lactam antibiotics against resistant strains.
Chemical PropertiesWhite Solid
OriginatorPfizer (USA)
UsesA semi-synthetic β-lactamase inhibitor. It is used in combination with β-lactam antibiotics as antibacterial.
DefinitionChEBI: Sulbactam sodium is an organooxygen compound and an organonitrogen compound. It is functionally related to an alpha-amino acid.
Manufacturing ProcessSulbactam sodium is semi-synthetic antibiotic of penicillinic group. Start material for it's synthesis is 6-aminopenicillanic acid. First 6-aminopenicillanic acid was isolated in 1957 year from benzylpenicilline as resalt of treating of it by penicillinaze. Benzylpenicilline is produced by microorganism of genus Streptomyces.
Further, 6-aminopenicillanic acid reacted with bromine, hydrochloric acid and NaNO2. As a result the 6,6-dibromopenicillanic acid was obtained.
6,6-Dibromopenicillanic acid was oxidized by KMnO4, to give 6,6-dibromo-1,1-The 6,6-dibromo-1,1-dioxopenicillanic acid in presence of Fe was converted to the 1,1-dioxopenicillanic acid (sulbactam acid). The sulbactam acid was treated by sodium 2-ethylhexanoate and crude sulbactam sodium was obtained.
Brand nameSULPERAZONE
Therapeutic FunctionBeta-lactamase inhibitor
General DescriptionSulbactam was synthesized by Pfizer Research Laboratories in 1977 in the course of screening for β-lactamase inhibitors. It shows strong activity against penicillinase and moderate activity against cephalosporinase. Sulbactam itself shows activity against some gramnegative bacteria but no activity against most pathogenic bacteria. The use of sulbactam in combination with cefoperazone, which is partially hydrolyzed by penicillinase, is under study along with its use as an esterified complex with ampicillin (sultamicillin) for therapy of cefoperazone-ampicillin-resistant infections.
Safety ProfilePoison by intravenous route. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and SOx
Sulbactam sodium Preparation Products And Raw materials
Raw materialsSodium 2-ethylhexanoate-->Sulbactam
Preparation Products3-oxopropanoic acid
Tag:Sulbactam sodium(69388-84-7) Related Product Information
ETHANE Dimethyl phthalate Dimethyl fumarate ISOHEPTANE Dimethyl sulfoxide Sodium formate Sodium carbonate Sodium bicarbonate Sodium 1-heptanesulfonate Sulbactam Sodium gluconate Sodium benzoate Sodium chloride N,N-Dimethylformamide Sodium hydroxide Dimethyl sebacate Dimethyl ether Heptane