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Lercanidipine hydrochloride

Lercanidipine hydrochloride structure

CAS No.: 132866-11-6

Chemical Name:: Lercanidipine hydrochloride

Synonyms: LERCANIDIPINE HCL;CLAP;mE10;R 75;BCL10;c-E10;CIPER;CarMen;Lercan;LerzaM

CBNumber:: CB0371085

Molecular Formula:: C36H42ClN3O6

Molecular Weight:: 648.19

MDL Number:: MFCD07773089

MOL File:: 132866-11-6.mol

MSDS File:: SDS

Last updated:2025-01-27 09:38:02

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Lercanidipine hydrochloride Properties

Melting point	175-177°C
storage temp.	2-8°C
solubility	Methanol[soluble in]
solubility	soluble in Methanol
form	powder
color	yellow
Merck	14,5446
InChIKey	WMFYOYKPJLRMJI-UHFFFAOYSA-N
SMILES	C1(C)NC(C)=C(C(OC(C)(C)CN(CCC(C2=CC=CC=C2)C2=CC=CC=C2)C)=O)C(C2=CC=CC([N+]([O-])=O)=C2)C=1C(OC)=O.[H]Cl
CAS DataBase Reference	132866-11-6(CAS DataBase Reference)
FDA UNII	OA8TFX68PE
UNSPSC Code	12352200
NACRES	NA.77

Pharmacokinetic data

Protein binding	>98%
Excreted unchanged in urine	50 (as metabolites)
Biological half-life	8-10 / Increased

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06

Signal word

Danger

Hazard statements

H301

Precautionary statements

P301+P310

Hazard Codes

Risk Statements

Safety Statements

36/37-45

RIDADR

UN 2811

WGK Germany

HS Code

2933.39.4100

Toxicity

LD50 in mice (mg/kg): 83 i.p.; 657 orally (Nardi)

NFPA 704

	0
2		0

Lercanidipine hydrochloride price More Price(41)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	L6668	Lercanidipine hydrochloride ≥98% (HPLC)	132866-11-6	10mg	$122.4	2024-03-01	Buy
Sigma-Aldrich	L6668	Lercanidipine hydrochloride ≥98% (HPLC)	132866-11-6	50mg	$643	2024-03-01	Buy
TCI Chemical	L0282	Lercanidipine Hydrochloride >98.0%(HPLC)(T)	132866-11-6	200mg	$16	2024-03-01	Buy
TCI Chemical	L0282	Lercanidipine Hydrochloride >98.0%(HPLC)(T)	132866-11-6	1g	$44	2024-03-01	Buy
Alfa Aesar	H36728	Lercanidipine hydrochloride 98%	132866-11-6	1g	$327.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
L6668	10mg	$122.4	Buy
L6668	50mg	$643	Buy
L0282	200mg	$16	Buy
L0282	1g	$44	Buy
H36728	1g	$327.65	Buy

Lercanidipine hydrochloride Chemical Properties,Uses,Production

Chemical Properties

Pale-Yellow Powder

Uses

long-acting dihydropyridine calcium channel blocker, antihypertensive

Uses

A dihydropyridine calcium channel blocker. Antihypertensive.

Definition

ChEBI: Lercanidipine hydrochloride is a diarylmethane.

brand name

Cardiovasc (Recor dati, Italy); Carmen (Recordati, Italy); Corifeo (Recordati, Italy); Lercadip (Recordati, Italy); Lercan (Recordati, Italy); Lercapin (Recordati, Italy); Lercaton (Recordati, Italy); Lerkamen (Recordati, Italy); Lerzam (Recordati, Italy); Renovia (Recordati, Italy); Vasodip (Recordati, Italy); Zandip (Recordati, Italy); Zanicor (Recordati, Italy).

Biological Activity

L-type Ca 2+ channel blocker that displays higher vascular selectivity than Felodipine (4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester ). Causes peripheral vasodilation with only weak negative inotropic activity. Antihypertensive.

Biochem/physiol Actions

Lercanidipine hydrochloride is a L-type (Cav1.2b) vascular channel antagonist; L-type (Cav1.2a) cardiac channel agonist voltage-dependent and highly lipophylic compound, which exhibits a slower onset and longer duration of action than other calcium channel antagonists; an antihypertensive agent in patients with mild-to-moderate hypertension; more vasoselective than lacidipine and amlodipine.

Lercanidipine hydrochloride synthesis

Synthesis of Lercanidipine hydrochloride from Lercanidipine

Lercanidipine hydrochloride Preparation Products And Raw materials

Raw materials

Lercanidipine Impurity 26 2-[(3-Nitrophenyl)methylene]-3-oxo-butanoic Acid 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl Ester Hydrochloride Butanoic acid, 3-oxo-,2-[(3,3-diphenylpropyl)MethylaMino]-1,1-diMethylethyl ester N-Methyl-3,3-diphenylpropylamine Lercanidipine

2,N-Dimethyl-N-(3,3-diphenylpropyl)-1-amino-2-propanol methyl 3-aminocrotonate Methyl 3-aminocrotonate 3-Nitrobenzaldehyde

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Preparation Products

Lercanidipine hydrochloride Suppliers

Global( 380)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Xuchang Hengsheng Pharmaceutical Co., Ltd	+86-03745692999 +86-13569491380	xccxn@xchsyy.com	China	15	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531157085	abby@chuanghaibio.com	China	8808	58
Hebei Yanxi Chemical Co., Ltd.	+8617531153977	allison@yan-xi.com	China	5854	58
Hangzhou Hyper Chemicals Limited	+86-0086-57187702781 +8613675893055	info@hyper-chem.com	China	295	58
Frapp's ChemicalNFTZ Co., Ltd.	+86 (576) 8169-6106	sales@frappschem.com	China	880	50
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29730	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21628	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29858	58

Supplier	Advantage
Xuchang Hengsheng Pharmaceutical Co., Ltd	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
Hangzhou Hyper Chemicals Limited	58
Frapp's ChemicalNFTZ Co., Ltd.	50
Capot Chemical Co.,Ltd.	60
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58

View Lastest Price from Lercanidipine hydrochloride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-04-23	Lercanidipine hydrochloride 132866-11-6	US $9.90 / KG	100KG	99%	10 tons	Hebei Chuanghai Biotechnology Co., Ltd
2025-03-07	Lercanidipine hydrochloride 132866-11-6	US $0.00 / kg	1kg	0.99	20 tons	Hebei Yanxi Chemical Co., Ltd.
2025-03-07	Lercanidipine hydrochloride 132866-11-6	US $0.00 / kg	1kg	0.99	20 tons	Hebei Yanxi Chemical Co., Ltd.

Lercanidipine hydrochloride
132866-11-6
US $9.90 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

Lercanidipine hydrochloride
132866-11-6
US $0.00 / kg
0.99
Hebei Yanxi Chemical Co., Ltd.

Lercanidipine hydrochloride
132866-11-6
US $0.00 / kg
0.99
Hebei Yanxi Chemical Co., Ltd.

132866-11-6(Lercanidipine hydrochloride)Related Search:

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N,N-Dimethylallylamine Topotecan hydrochloride 2,5-Dimethylpyridine Chromium picolinate Dimethyl sulfate

DIMETHYLAMINOPYRIDINE, POLYMER-BOUND Dimethyl sulfoxide 1-AdaMantanethylaMine

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1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester hydrochloride LERCANIDIPINE HYDROCHLORIDE 1,4-Dihydro-2,6-dimethyl-4-(3-nittrophenyl)-3,5-pyridinedicarboxylicAcid2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimeth 1,4-Dihydro-2,6-dimethyl-4-(3-nittrophenyl)-3,5-pyridinedicarboxylic Acid 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl Methyl Ester Hydrochloride 3-(1-((3,3-Diphenylpropyl)(methyl)amino)-2-methylpropan-2-yl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride 3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-diMethyl-4-(3-nitrophenyl)-,3-[2-[(3,3-diphenylpropyl)MethylaMino]-1,1-diMethylethyl] 5-Methyl ester,hydrochloride (1:1) 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester 3,5-pyridinedicarboxylic acid hydrochloride B-cell CLL/lymphoma 10 B-cell lymphoma/leukemia 10 BCL10 CARD-containing molecule enhancing NF-κ-B BCL-10 human c-E10 CIPER CLAP mE10 LERCANIDIPINEHYDROCHLORIDE(FORR&DONLY) Lercanidipine hemihydrate hydrochloride 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid O3-[2-[3,3-diphenylpropyl(methyl)amino]-1,1-dimethyl-ethyl] ester O5-methyl ester hydrochloride 3-O-[1-[3,3-diphenylpropyl(methyl)amino]-2-methylpropan-2-yl] 5-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride O3-[1-[3,3-diphenylpropyl(methyl)amino]-2-methyl-propan-2-yl] O5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride Lercaridipine Cardiovasc CarMen Corifeo Lercadip Lercan Lercapin Lercaton LerkaMen LerzaM R 75 Renovia Vasodip Zandip Zanicor Lercanidipine hydrochloride heMihydrate 1,4-dihydro-2,6-diMethyl-4-(3-nitrophenyl)-3,5- Lercanidipine Impurity 1 Lercanidipine hydrochloride hemihydrate, ≥98% (HPLC) -1,4-dihydropyridine-3,5-dicarboxylate hydrochloride -2-methylpropan-2-yl) 3-(1-((3,3-Diphenylpropyl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl) LercanidipineHydrochloride> ercanidipine hydrochL Lercanidipine hydrochloride USP/EP/BP Lercanidipine HCL WS Lercanidipine HCl (REC 15-237, Lercadip, Lerdip, Zanidip) Lercanidipine HydrochlorideQ: What is Lercanidipine Hydrochloride Q: What is the CAS Number of Lercanidipine Hydrochloride Q: What is the storage condition of Lercanidipine Hydrochloride Q: What are the applications of Lercanidipine Hydrochloride TIANFU CHEM Lercanidipine hydrochloride NSC 405365 NSC405365 NSC-405365 LERCANIDIPINE HCL Lercanidipine HCL Powder USP Standard Lercanidpine Hydrochoride Lecardipine hydrochloride