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5-ETHYL-4-(4-METHOXY-PHENYL)-THIAZOL-2-YLAMINE

5-ETHYL-4-(4-METHOXY-PHENYL)-THIAZOL-2-YLAMINE Structure
5-ETHYL-4-(4-METHOXY-PHENYL)-THIAZOL-2-YLAMINE structure
CAS No.
493028-20-9
Chemical Name:
5-ETHYL-4-(4-METHOXY-PHENYL)-THIAZOL-2-YLAMINE
Synonyms
CBFβ Inhibitor;CBFβ Inhibitor;TIMTEC-BB SBB011699;Runx1-CBFβ interaction inhibitor 1;2-Thiazolamine, 5-ethyl-4-(4-methoxyphenyl)-;CBFβ Inhibitor - CAS 493028-20-9 - Calbiochem;5-ETHYL-4-(4-METHOXY-PHENYL)-THIAZOL-2-YLAMINE;5-ethyl-4-(4-methoxyphenyl)-1,3-thiazol-2-amine
CBNumber:
CB0412427
Molecular Formula:
C12H14N2OS
Molecular Weight:
234.32
MDL Number:
MFCD02232182
MOL File:
Mol file
Last updated:2024-11-18 17:01:59
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5-ETHYL-4-(4-METHOXY-PHENYL)-THIAZOL-2-YLAMINE Properties

Boiling point 421.6±40.0 °C(Predicted)
Density 1.192±0.06 g/cm3(Predicted)
storage temp. +2C to +8C
solubility DMF: 50 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 30 mg/ml; Ethanol: 25 mg/ml
form Tan solid
pka 5.00±0.10(Predicted)

SAFETY

Risk and Safety Statements

Hazard Codes  Xi
HazardClass  IRRITANT

5-ETHYL-4-(4-METHOXY-PHENYL)-THIAZOL-2-YLAMINE price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 16771 CBFβ Inhibitor ≥98% 493028-20-9 5mg $72 2024-03-01 Buy
Cayman Chemical 16771 CBFβ Inhibitor ≥98% 493028-20-9 10mg $135 2024-03-01 Buy
Cayman Chemical 16771 CBFβ Inhibitor ≥98% 493028-20-9 25mg $301 2024-03-01 Buy
ApexBio Technology C3398 CBFβInhibitor 493028-20-9 25mg $342 2021-12-16 Buy
AK Scientific 4241AE 5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine 493028-20-9 1g $432 2021-12-16 Buy
Product number Packaging Price Buy
16771 5mg $72 Buy
16771 10mg $135 Buy
16771 25mg $301 Buy
C3398 25mg $342 Buy
4241AE 1g $432 Buy

5-ETHYL-4-(4-METHOXY-PHENYL)-THIAZOL-2-YLAMINE Chemical Properties,Uses,Production

Description

Core binding factors (CBFs) are heterodimeric transcription factors consisting of a DNA-binding CBFα component (a RUNX protein) and an enhancer of binding, CBFβ. CBF dimers have central roles in hematopoiesis and, when dysfunctional, in leukemias. CBFβ inhibitor is a small molecule that binds to CBFβ and inhibits its association with Runx1 (IC50 = 3.2 μM). It blocks CBFβ-Runx1 interactions in ME-1 cells, acute myeloid leukemia cells harboring dysfunctional CBF, reducing proliferation without toxicity.

Uses

Core binding factors (CBFs) are heterodimeric transcription factors consisting of a DNA-binding CBFα component (a RUNX protein) and an enhancer of binding, CBFβ. CBF dimers have central roles in hematopoiesis and, when dysfunctional, in leukemias. CBFβ inhibitor is a small molecule that binds to CBFβ and inhibits its association with Runx1 (IC50 = 3.2 μM). It blocks CBFβ-Runx1 interactions in ME-1 cells, acute myeloid leukemia cells harboring dysfunctional CBF, reducing proliferation without toxicity.

5-ETHYL-4-(4-METHOXY-PHENYL)-THIAZOL-2-YLAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

5-ETHYL-4-(4-METHOXY-PHENYL)-THIAZOL-2-YLAMINE Suppliers

Global( 29)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32112 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52925 58
BOC Sciences 16314854226 info@bocsci.com United States 9923 65
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
Changzhou Hopschain Chemical Co.,Ltd. 0519-85528066 13775048983 sales@hopschem.com China 31553 55
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11217 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8140 58
Changzhou Furuisi Biotechnology Co., Ltd 0519-85524369 3477467573@qq.com China 8617 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24647 58
Shanghai Haohong Scientific Co., Ltd. 400-400-8210725 malulu@leyan.com China 39953 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
BOC Sciences 65
Shanghai EFE Biological Technology Co., Ltd. 58
Changzhou Hopschain Chemical Co.,Ltd. 55
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
MedBioPharmaceutical Technology Inc 58
Changzhou Furuisi Biotechnology Co., Ltd 58
TargetMol Chemicals Inc. 58
Shanghai Haohong Scientific Co., Ltd. 58

View Lastest Price from 5-ETHYL-4-(4-METHOXY-PHENYL)-THIAZOL-2-YLAMINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
CBFβ Inhibitor pictures 2024-11-18 CBFβ Inhibitor
493028-20-9
 US $29.00-85.00 / mg 96.50% 10g TargetMol Chemicals Inc.
  • CBFβ Inhibitor pictures
  • CBFβ Inhibitor
    493028-20-9
  • US $29.00-85.00 / mg
  • 96.50%
  • TargetMol Chemicals Inc.

5-ETHYL-4-(4-METHOXY-PHENYL)-THIAZOL-2-YLAMINE Spectrum

5-ETHYL-4-(4-METHOXY-PHENYL)-THIAZOL-2-YLAMINE(493028-20-9)1HNMR
TIMTEC-BB SBB011699 5-ETHYL-4-(4-METHOXY-PHENYL)-THIAZOL-2-YLAMINE CBFβ Inhibitor 5-ethyl-4-(4-methoxyphenyl)-1,3-thiazol-2-amine CBFβ Inhibitor - CAS 493028-20-9 - Calbiochem CBFβ Inhibitor 2-Thiazolamine, 5-ethyl-4-(4-methoxyphenyl)- Runx1-CBFβ interaction inhibitor 1 493028-20-9