ChemicalBook >제품 카탈로그 >5-에틸-4-(4-메톡시-페닐)-티아졸-2-일라민

5-에틸-4-(4-메톡시-페닐)-티아졸-2-일라민

5-에틸-4-(4-메톡시-페닐)-티아졸-2-일라민 구조식 이미지

카스 번호:: 493028-20-9

한글명:: 5-에틸-4-(4-메톡시-페닐)-티아졸-2-일라민

동의어(한글):: 5-에틸-4-(4-메톡시-페닐)-티아졸-2-일라민

상품명:: 5-ETHYL-4-(4-METHOXY-PHENYL)-THIAZOL-2-YLAMINE

동의어(영문):: CBFβ Inhibitor;CBFβ Inhibitor;TIMTEC-BB SBB011699;Runx1-CBFβ interaction inhibitor 1;2-Thiazolamine, 5-ethyl-4-(4-methoxyphenyl)-;CBFβ Inhibitor - CAS 493028-20-9 - Calbiochem;5-ETHYL-4-(4-METHOXY-PHENYL)-THIAZOL-2-YLAMINE;5-ethyl-4-(4-methoxyphenyl)-1,3-thiazol-2-amine

CBNumber:: CB0412427

분자식:: C12H14N2OS

포뮬러 무게:: 234.32

MOL 파일:: Mol file

속성

안전

용도

공급 업체 30

5-에틸-4-(4-메톡시-페닐)-티아졸-2-일라민 속성

끓는 점: 421.6±40.0 °C(Predicted)

밀도: 1.192±0.06 g/cm3(Predicted)

저장 조건: +2C to +8C

용해도: DMF: 50 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 30 mg/ml; Ethanol: 25 mg/ml

물리적 상태: 황갈색 고체

산도 계수 (pKa): 5.00±0.10(Predicted)

안전

위험품 표기	Xi
위험 등급	IRRITANT

5-에틸-4-(4-메톡시-페닐)-티아졸-2-일라민 C화학적 특성, 용도, 생산

개요

Core binding factors (CBFs) are heterodimeric transcription factors consisting of a DNA-binding CBFα component (a RUNX protein) and an enhancer of binding, CBFβ. CBF dimers have central roles in hematopoiesis and, when dysfunctional, in leukemias. CBFβ inhibitor is a small molecule that binds to CBFβ and inhibits its association with Runx1 (IC₅₀ = 3.2 μM). It blocks CBFβ-Runx1 interactions in ME-1 cells, acute myeloid leukemia cells harboring dysfunctional CBF, reducing proliferation without toxicity.

용도

Core binding factors (CBFs) are heterodimeric transcription factors consisting of a DNA-binding CBFα component (a RUNX protein) and an enhancer of binding, CBFβ. CBF dimers have central roles in hematopoiesis and, when dysfunctional, in leukemias. CBFβ inhibitor is a small molecule that binds to CBFβ and inhibits its association with Runx1 (IC50 = 3.2 μM). It blocks CBFβ-Runx1 interactions in ME-1 cells, acute myeloid leukemia cells harboring dysfunctional CBF, reducing proliferation without toxicity.

5-에틸-4-(4-메톡시-페닐)-티아졸-2-일라민 준비 용품 및 원자재

원자재

준비 용품

5-에틸-4-(4-메톡시-페닐)-티아졸-2-일라민 공급 업체

글로벌( 30)공급 업체

공급자	전화	이메일	국가	제품 수	이점
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
BOC Sciences	16314854226	info@bocsci.com	United States	9926	65
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9806	58
Changzhou Hopschain Chemical Co.,Ltd.	0519-85528066 13775048983	sales@hopschem.com	China	31557	55
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8141	58
Changzhou Furuisi Biotechnology Co., Ltd	0519-85524369	3477467573@qq.com	China	8618	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24647	58
Suzhou Zhixin Biotechnology Co., Ltd.	0512-65118909 15162312715	sales@szzxbio.com	China	2994	58