ChemicalBook >> CAS DataBase List >>DESMETHYL LOPERAMIDE
DESMETHYL LOPERAMIDE
- CAS No.
- 66164-07-6
- Chemical Name:
- DESMETHYL LOPERAMIDE
- Synonyms
- dLop;R 20905;DESMETHYL LOPERAMIDE;N-Desmethyl Loperamid;N-Desmethyl Loperamide;Desmethylloperamide D5;Desmethyl loperamide HCl;4-(4-Chlorophenyl)-4-hydroxy-N-methyl-a,a-diphenyl-1-piperidinebutanamide;4-(4-Chlorophenyl)-4-hydroxy-N-Methyl-α,α-diphenyl-1-piperidinebutanaMide;1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N-methyl-α,α-diphenyl-
- CBNumber:
- CB0462831
- Molecular Formula:
- C28H31ClN2O2
- Molecular Weight:
- 463.01
- MDL Number:
- MFCD08063667
- MOL File:
- 66164-07-6.mol
Last updated:2024-10-23 13:36:13
| Melting point | 219-221?C |
|---|---|
| Boiling point | 678.3±55.0 °C(Predicted) |
| Density | 1?+-.0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | DMF: 2 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 1 mg/ml |
| form | A crystalline solid |
| pka | 13.85±0.20(Predicted) |
| FDA UNII | 0R07BFN7L3 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501 | |||||||||
| HS Code | 9999999999 | |||||||||
| NFPA 704 |
|
DESMETHYL LOPERAMIDE price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 16126 | N-Desmethyl-loperamide ≥98% | 66164-07-6 | 500μg | $184 | 2024-03-01 | Buy |
| Cayman Chemical | 16126 | N-Desmethyl-loperamide ≥98% | 66164-07-6 | 1mg | $330 | 2024-03-01 | Buy |
| Cayman Chemical | 16126 | N-Desmethyl-loperamide ≥98% | 66164-07-6 | 5mg | $984 | 2024-03-01 | Buy |
| TRC | D291840 | N-DesmethylLoperamide | 66164-07-6 | 2mg | $365 | 2021-12-16 | Buy |
| Usbiological | 008596 | N-Desmethyl Loperamide | 66164-07-6 | 1mg | $475 | 2021-12-16 | Buy |
DESMETHYL LOPERAMIDE Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
A metabolite of Loperamide; a new and improved PET radiotracer for imaging P-gp function
Uses
Loperamide is an opiate which potently and selectively activates μ opioid receptors (Ki = 0.16 nM) exclusively in the periphery. N-Desmethyl-loperamide (dLop) is a major metabolite of loperamide. Like loperamide, dLop is a substrate of the ATP-dependent efflux transporter, P-glycoprotein. As a result, both the parent compound and the metabolite display restricted passage through the blood-brain barrier. dLop in biological samples can be analyzed by a variety of methods.
Definition
ChEBI: A monocarboxylic acid amide that is the methylamide of 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenylbutanoic acid.
DESMETHYL LOPERAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 50)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9639 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12373 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38631 | 58 | |
| Hebei Miaoyin Technology Co.,Ltd | +86-17367732028 +86-17367732028 | kathy@hbyinsheng.com | China | 3512 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52924 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
View Lastest Price from DESMETHYL LOPERAMIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-24 | N-Desmethyl Loperamide
66164-07-6
|
US $2460.00-825.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2022-02-18 | DESMETHYL LOPERAMIDE
66164-07-6
|
US $0.00 / gram | 1gram | 99% | 10kg | Zhejiang J&C Biological Technology Co.,Limited |
-
- N-Desmethyl Loperamide
66164-07-6
- US $2460.00-825.00 / mg
- TargetMol Chemicals Inc.
-
- DESMETHYL LOPERAMIDE
66164-07-6
- US $0.00 / gram
- 99%
- Zhejiang J&C Biological Technology Co.,Limited
66164-07-6(DESMETHYL LOPERAMIDE)Related Search:
DESMETHYL LOPERAMIDE
4-(4-Chlorophenyl)-4-hydroxy-N-methyl-a,a-diphenyl-1-piperidinebutanamide
N-Desmethyl Loperamide
R 20905
Desmethyl loperamide HCl
Desmethylloperamide D5
4-(4-Chlorophenyl)-4-hydroxy-N-Methyl-α,α-diphenyl-1-piperidinebutanaMide
1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N-methyl-α,α-diphenyl-
dLop
N-Desmethyl Loperamid
4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-methyl-2,2-diphenylbutanamide
66164-07-6
C28H31ClN2O2HCl
C28H31ClN2O2
Amines
Heterocycles
Intermediates & Fine Chemicals
Metabolites & Impurities
Pharmaceuticals