TS 155-2
- CAS No.
- 1314486-37-7
- Chemical Name:
- TS 155-2
- Synonyms
- 2E-butenedioicacid-1-[(2R,4R,5S,6R)-tetrahydro-2-hydroxy-2-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14E)-10-hydroxy-3-methoxy-7,9,11,13,15-pentamethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-5-methyl-6-(1-methylethyl)-2H-pyran-4-yl]ester;2-Butenedioic acid (2E)-, 1-[(2R,4R,5S,6R)-tetrahydro-2-hydroxy-2-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14E)-10-hydroxy-3-methoxy-7,9,11,13,15-pentamethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-5-methyl-6-(1-methylethyl)-2H-pyran-4-yl] ester
- CBNumber:
- CB04666837
- Molecular Formula:
- C39H60O11
- Molecular Weight:
- 704.89
- MDL Number:
- MOL File:
- 1314486-37-7.mol
TS 155-2 price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 20689 | TS 155-2 ≥95% | 1314486-37-7 | 1mg | $242 | 2024-03-01 | Buy |
| Cayman Chemical | 20689 | TS 155-2 ≥95% | 1314486-37-7 | 5mg | $1087 | 2024-03-01 | Buy |
| ApexBio Technology | C4021 | TS155-2 | 1314486-37-7 | 5mg | $1213 | 2021-12-16 | Buy |
| AK Scientific | 1451EN | (E)-4-[(2R,4R,5S,6R)-2-Hydroxy-2-[(2S,3R,4S)-3-hydroxy-4-[(2R,3S,4Z,6Z,9S,10S,11R,12Z,14Z)-10-hydroxy-3-methoxy-7,9,11,13,15-pentamethyl-16-oxo-1-oxacyclohexadeca-4,6,12,14-tetraen-2-yl]pentan-2-yl]-5-methyl-6-propan-2-yloxan-4-yl]oxy-4-oxobut-2-enoicacid | 1314486-37-7 | 5mg | $1309 | 2021-12-16 | Buy |
| ApexBio Technology | C4021 | TS155-2 | 1314486-37-7 | 1mg | $276 | 2021-12-16 | Buy |
TS 155-2 Chemical Properties,Uses,Production
Biological Activity
ts 155-2, is a macrocyclic lactone related to hygrolidin, is produced by a different streptomyces species found in oil. it blocks thrombin-evoked calcium (ca2+) entry into cells. ts155-2 exerts hypotensive, anti-platelet, anti-ischaemic and anti-inflammatory activity showed on the original patent, however, no literature investigation of ts155-2 is available.a rapid increase in cytosolic ca2+ is related to the signal transduction events following the induction of thrombin in a wide range of cell types which include fibroblasts, platelets, megakaryocytes, endothelium and smooth muscle. thrombin-stimulated ca2+ mobilization has been shown to be involved in both ca2+ release from internal storage sites and ca2+influx and has been extensively studied in human platelets. thrombin triggers phospholipase c resulting in the rapid generation of inositol 1,4,5-trisphosphate (ip3), which elicits the release of ca2+ from ip3-sensitive stores. however, the thrombin-induced ca2+ influx is still an area of contention [1].
References
[1]. somasundaram, b., mason, m., & mahaut-smith, m. thrombin-dependent calcium signalling in single human erythroleukaemia cells. the journal of physiology.1997;501(3):485-495.
TS 155-2 Preparation Products And Raw materials
Raw materials
Preparation Products
TS 155-2 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9704 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
| ApexBio Technology | -- | sales@apexbt.com | United States | 6254 | 58 |