ChemicalBook >> CAS DataBase List >>SRT3025 Hydrochloride
SRT3025 Hydrochloride
- CAS No.
- 2070015-26-6
- Chemical Name:
- SRT3025 Hydrochloride
- Synonyms
- SRT3025 Hydrochloride;SIRTUIN MODULATOR 1;SRT3025 HCL;Inhibitor,Sirtuin,Sirtuin modulator1,inhibit,Sirtuin modulator-1,Sirtuin modulator 1;5-(3-Methoxypropyl)-2-phenyl-N-(2-(6-(pyrrolidin-1-ylmethyl)thiazolo[5,4-b]pyridin-2-yl)phenyl)thiazole-4-carboxamide hydrochloride
- CBNumber:
- CB04672236
- Molecular Formula:
- C31H32ClN5O2S2
- Molecular Weight:
- 606.2
- MDL Number:
- MOL File:
- 2070015-26-6.mol
Last updated:2025-01-27 09:38:02
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501 | |||||||||
| NFPA 704 |
|
SRT3025 Hydrochloride price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | S490940 | SRT3025Hydrochloride | 2070015-26-6 | 1mg | $180 | 2021-12-16 | Buy |
| AK Scientific | 6186EF | SRT3025Hydrochloride | 2070015-26-6 | 5mg | $190 | 2021-12-16 | Buy |
| ChemScene | CS-5444 | Sirtuinmodulator1 99.44% | 2070015-26-6 | 10mg | $225 | 2021-12-16 | Buy |
| ChemScene | CS-5444 | Sirtuinmodulator1 99.44% | 2070015-26-6 | 50mg | $675 | 2021-12-16 | Buy |
| ChemScene | CS-5444 | Sirtuinmodulator1 99.44% | 2070015-26-6 | 1mg | $65 | 2021-12-16 | Buy |
SRT3025 Hydrochloride Chemical Properties,Uses,Production
Uses
SRT3025 Hydrochloride is a SIRT1 activator which in turn inhibits RANKL-induced osteoclastogenesis in bone marrow-derived macrophages. Decreases osteoclast-mediated bone resporption.
Biological Activity
SRT3025 is an orally active sirtuin 1 activator (Sirt1 EC1.5 ≤1 μM, Emax ≥150% and <300%) th at reduces cellular acetylation of Sirt1 substrates FoxO1 (induced by RANKL ) and histone 3 (1-10 μM; murine bone marrow macrophages) and exhibits in vivo efficacy in a murine atherosclerosis model (3.18 g/kg high-cholesterol diet; mice) and ovariectomy-induced bone loss in female mice (50 & 100 mg/kg via daily p.o.).
SRT3025 Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
SRT3025 Hydrochloride Suppliers
Global( 35)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| Nanjing Doge Biomedical Technology Co., Ltd | +86-25-58227606 +86-15305155328 | sales@dogechemical.com | China | 4128 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38631 | 58 | |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57505 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66099280 17798518460 | cfzhang@aikonchem.com | China | 19915 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9805 | 58 |
| Qingdao IniKem BioPharmaTech Co.,Ltd | 0532-58268780 | sales@inikem.com | China | 296 | 55 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 4009686088 | 3193328036@qq.com | China | 29764 | 68 |
| Guangzhou Tomums Life Science Co., Ltd. | 020-31155029 18902330969 | sales@tomums.cn | China | 4696 | 58 |
View Lastest Price from SRT3025 Hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | Sirtuin modulator 1
2070015-26-6
|
US $31.00-83.00 / mg | 99.1% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-11-19 | Sirtuin modulator 1
2070015-26-6
|
US $31.00-83.00 / mg | 99.1% | 10g | TargetMol Chemicals Inc. |
-
- Sirtuin modulator 1
2070015-26-6
- US $31.00-83.00 / mg
- 99.1%
- TargetMol Chemicals Inc.
-
- Sirtuin modulator 1
2070015-26-6
- US $31.00-83.00 / mg
- 99.1%
- TargetMol Chemicals Inc.
SRT3025 Hydrochloride
SIRTUIN MODULATOR 1;SRT3025 HCL
Inhibitor,Sirtuin,Sirtuin modulator1,inhibit,Sirtuin modulator-1,Sirtuin modulator 1
5-(3-Methoxypropyl)-2-phenyl-N-(2-(6-(pyrrolidin-1-ylmethyl)thiazolo[5,4-b]pyridin-2-yl)phenyl)thiazole-4-carboxamide hydrochloride
2070015-26-6