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Bozepinib
- CAS No.
- 1207993-83-6
- Chemical Name:
- Bozepinib
- Synonyms
- Bozepinib;4,1-Benzoxazepine, 3-(2,6-dichloro-9H-purin-9-yl)-1,2,3,5-tetrahydro-1-[(4-nitrophenyl)sulfonyl]-
- CBNumber:
- CB04718592
- Molecular Formula:
- C20H14Cl2N6O5S
- Molecular Weight:
- 521.33
- MDL Number:
- MOL File:
- 1207993-83-6.mol
Bozepinib Chemical Properties,Uses,Production
Enzyme inhibitor
This potent antitumor agent (FW = 521.33 g/mol), sysyematically known as (RS)-2,6-dichloro-9-[1-(p-nitrobenzenesulfonyl)-1,2,3,5-tetrahydro-4,1- benzoxazepin-3-yl]-9H-purine, induces apoptosis in breast and colon cancer cells via inhibition (IC50 = 0.3–2 μM) of the the double-stranded RNAdependent protein kinase, PKR, but not p53. Moreover, interferon enhances cytotoxicity of bozepinib in colon and breast cancer cells by increasing apoptotic cell death.
Bozepinib Preparation Products And Raw materials
Raw materials
Preparation Products
Bozepinib Suppliers
Global( 7)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 | 757984502@qq.com | China | 892 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9806 | 58 |
| ShangHai ChuanQian Chemcial Technique Centre | 15869524721 | 3525679403@qq.com | China | 3897 | 58 |
| Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 | 3477467573@qq.com | China | 8618 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24647 | 58 |
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | 024-024-88590548 18341751992 | 757984502@qq.com | China | 891 | 58 |
Bozepinib
4,1-Benzoxazepine, 3-(2,6-dichloro-9H-purin-9-yl)-1,2,3,5-tetrahydro-1-[(4-nitrophenyl)sulfonyl]-
1207993-83-6