ChemicalBook >> CAS DataBase List >>K-604 dihydrochloride
K-604 dihydrochloride
- CAS No.
- 217094-32-1
- Chemical Name:
- K-604 dihydrochloride
- Synonyms
- K-604 2HCl;K-604 (K604);K-604 >=98% (HPLC);K-604 dihydrochloride;2-(4-(2-((1H-Benzo[d]imidazol-2-yl)thio)ethyl)piperazin-1-yl)-N-(6-methyl-2,4-bis(methylthio)pyridin-3-yl)acetamide dihydrochloride;K604,K604 dihydrochloride,acyl-CoA:cholesterol acyltransferase,K-604,inhibit,K 604,Inhibitor,Diacylglycerol acyltransferase,Diglyceride acyltransferase,mono- acylglycerol acyltransferase,Acyltransferase,K 604 dihydrochloride
- CBNumber:
- CB04797074
- Molecular Formula:
- C23H31ClN6OS3
- Molecular Weight:
- 539.17
- MDL Number:
- MOL File:
- 217094-32-1.mol
Last updated:2024-07-02 08:54:58
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
K-604 dihydrochloride price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1837 | K-604 ≥98% (HPLC) | 217094-32-1 | 5mg | $128 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML1837 | K-604 ≥98% (HPLC) | 217094-32-1 | 25mg | $313.8 | 2024-03-01 | Buy |
| ChemScene | CS-0018788 | K-604dihydrochloride >99.0% | 217094-32-1 | 10mg | $390 | 2021-12-16 | Buy |
| ChemScene | CS-0018788 | K-604dihydrochloride >99.0% | 217094-32-1 | 5mg | $230 | 2021-12-16 | Buy |
| DC Chemicals | DC21196 | K-604 >98% | 217094-32-1 | 100mg | $700 | 2021-12-16 | Buy |
K-604 dihydrochloride Chemical Properties,Uses,Production
Biological Activity
K-604 dihydrochloride is a potent and selective acyl-CoA:cholesterol acyltransferase 1 (ACAT-1) inhibitor with IC50 of 0.45±0.06 μM.
in vivo
Using F1B hamsters, an animal model susceptible to diet-induced hyperlipidemia and atherosclerosis, the effects of K-604 dihydrochloride on aortic lesion areas and plasma cholesterol levels are assessed.
target
| ACAT-1 < span> 0.45 μM (IC 50 ) | ACAT-2 102.85 μM (IC 50 ) |
K-604 dihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
K-604 dihydrochloride Suppliers
Global( 26)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4428 | 55 |
| Shanghai Rechem science Co., Ltd. | 21-31433387 15618786686 | sales@rechemscience.com | China | 2993 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9730 | 58 |
| Henan Weituxi Chemical Technology Co., Ltd. | 0371-63284658 18135795563 | 2885349392@qq.com | China | 9995 | 58 |
| DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9412 | 58 |
| Changzhou Chenhong Biotechnology Co., Ltd. | 0519-85788828 13775037613 | sales@chemrenpharm.com | China | 3574 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Shanghai Luofa Biochemical Technology Co., Ltd. | 021-51111890 15317326293 | sales@molnova.com | China | 4196 | 58 |
K-604 dihydrochloride
K-604
(K604)
K-604 >=98% (HPLC)
K-604 2HCl
2-(4-(2-((1H-Benzo[d]imidazol-2-yl)thio)ethyl)piperazin-1-yl)-N-(6-methyl-2,4-bis(methylthio)pyridin-3-yl)acetamide dihydrochloride
K604,K604 dihydrochloride,acyl-CoA:cholesterol acyltransferase,K-604,inhibit,K 604,Inhibitor,Diacylglycerol acyltransferase,Diglyceride acyltransferase,mono- acylglycerol acyltransferase,Acyltransferase,K 604 dihydrochloride
217094-32-1