ChemicalBook >> CAS DataBase List >>2-Hydroxy-4-(trifluoromethyl)quinoline
2-Hydroxy-4-(trifluoromethyl)quinoline
- CAS No.
- 25199-84-2
- Chemical Name:
- 2-Hydroxy-4-(trifluoromethyl)quinoline
- Synonyms
- BUTTPARK 33\04-80;4-(Trifluoromethyl)quinolin-2-ol;4-Trifluoromethyl-1H-quinolin-2-one;4-trifluoroMethyl-2(1H)-quinolinone;4-(trifluoromethyl)quinolin-2(1H)-one;2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE;4--(TrifluoroMethyl)quinoline-2(H)-one;2-hydroxy-4-(trifluoroMethyl)quinqline;4-Trifluoromethyl-2(1H)-quinolinone,97%;2(1H)-Quinolinone, 4-(trifluoromethyl)-
- CBNumber:
- CB0496696
- Molecular Formula:
- C10H6F3NO
- Molecular Weight:
- 213.16
- MDL Number:
- MFCD03407380
- MOL File:
- 25199-84-2.mol
- MSDS File:
- SDS
Last updated:2024-01-18 08:48:14
| Melting point | >240°C |
|---|---|
| Boiling point | 284 ºC |
| Density | 1.391 |
| Flash point | 126 ºC |
| storage temp. | Sealed in dry,Room Temperature |
| form | Solid |
| color | White |
| InChI | InChI=1S/C10H6F3NO/c11-10(12,13)7-5-9(15)14-8-4-2-1-3-6(7)8/h1-5H,(H,14,15) |
| InChIKey | UUROBWTVZZNDFD-UHFFFAOYSA-N |
| SMILES | N1C2=C(C=CC=C2)C(C(F)(F)F)=CC1=O |
| CAS DataBase Reference | 25199-84-2 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Safety Statements | 24/25 | |||||||||
| HS Code | 29339900 | |||||||||
| NFPA 704 |
|
2-Hydroxy-4-(trifluoromethyl)quinoline price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Alfa Aesar | H61732 | 4-Trifluoromethyl-2(1H)-quinolinone, 97% | 25199-84-2 | 1g | $264 | 2024-03-01 | Buy |
| Alfa Aesar | H61732 | 4-Trifluoromethyl-2(1H)-quinolinone, 97% | 25199-84-2 | 250mg | $92.2 | 2023-06-20 | Buy |
| TRC | T900055 | 4-(trifluoromethyl)quinolin-2(1H)-one | 25199-84-2 | 50mg | $90 | 2021-12-16 | Buy |
| Matrix Scientific | 074152 | 2-Hydroxy-4-(trifluoromethyl)quinoline 95+% | 25199-84-2 | 1g | $416 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 37718 | 2-Hydroxy-4-(trifluoromethyl)quinoline 95+% | 25199-84-2 | 1g | $447 | 2021-12-16 | Buy |
2-Hydroxy-4-(trifluoromethyl)quinoline Chemical Properties,Uses,Production
Chemical Properties
White solid
Synthesis
4-Trifluoromethylquinolin-2(1H)-one was prepared by reacting aniline and ethyl-4,4,4-trifluoroacetoacetate stirred in toluene.
Experimental Procedure: In a 1 L round flask fitted with a reflux condenser a mixture of 25.60 g aniline, 50.0 g ethyl-4,4,4-trifluoroacetoacetate 300 ml toluene was heated to reflux in an oil bath at 130 °C. After 20 min 3 ml water was added and the mixture was heated at reflux for another 24 h. the reaction mixture was cooled to room temperature and concentrated under reduced pressure. A round flask with 200 mL H2SO4 was heated to 80°C and the crude oil from the step before was added in portions to the H2SO4 keeping the internal temperature below 90°C, total addition time was approximately 40 min. After addition was complete, the mixture was stirred at 80°C for 1 h, cooled and poured onto 400 g crushed ice. The resulting solids were filtered, washed with water, and dried under vacuum at 40°C to give 33.0 g (50%) product (2-Hydroxy-4-(trifluoromethyl)quinoline) as a colorless solid.
Synthesis of 2-Hydroxy-4-(trifluoromethyl)quinoline from Aniline and Ethyl 4,4,4-trifluoroacetoacetate
2-Hydroxy-4-(trifluoromethyl)quinoline Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 118)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hongxiong | +undefined18915499068 | Suzhouhongxiong@163.com | China | 120 | 58 |
| Hangzhou FandaChem Co.,Ltd. | +8615858145714 | FandaChem@Gmail.com | China | 9214 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29884 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8838 | 58 |
View Lastest Price from 2-Hydroxy-4-(trifluoromethyl)quinoline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-03-09 | 2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE
25199-84-2
|
US $1.10 / g | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2019-07-06 | 2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE
25199-84-2
|
US $1.00 / kg | 1kg | 98% | 200KG | Career Henan Chemical Co |
-
- 2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE
25199-84-2
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- 2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE
25199-84-2
- US $1.00 / kg
- 98%
- Career Henan Chemical Co
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1of4
BUTTPARK 33\04-80
2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE
4-(Trifluoromethyl)quinolin-2-ol
4-Trifluoromethyl-1H-quinolin-2-one
2-Hydroxy-4-(trifluoromethyl)quinoline ,98%
4-(trifluoromethyl)quinolin-2(1H)-one
2-hydroxy-4-(trifluoroMethyl)quinqline
4--(TrifluoroMethyl)quinoline-2(H)-one
4-trifluoroMethyl-2(1H)-quinolinone
2(1H)-Quinolinone, 4-(trifluoromethyl)-
4-Trifluoromethyl-2(1H)-quinolinone,97%
2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE ISO 9001：2015 REACH
25199-84-2
C10H6F3NO