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3-(Trifluoromethyl)benzaldehyde

3-(Trifluoromethyl)benzaldehyde structure

CAS No.: 454-89-7

Chemical Name:: 3-(Trifluoromethyl)benzaldehyde

Synonyms: MTF-BAD;3-(three fluoroMethyl;Cinacalcet Impurity 56;3-TRIFLUORMETHYLBENZALDEHYDE;m-Trifuoromethylbenzaldehyde;M-TRIFLUOROMETHYLBENZALDEHYDE;3-TRIFLUOROMETHYLBENZYLDEHYDE;Alpha-Trifluoro-M-tolualdehyde;A,A,A-TRIFLUORO-3-TOLUALDEHYDE;A,A,A-TRIFLUORO-M-TOLUALDEHYDE

CBNumber:: CB2759919

Molecular Formula:: C8H5F3O

Molecular Weight:: 174.12

MDL Number:: MFCD00003373

MOL File:: 454-89-7.mol

MSDS File:: SDS

Last updated:2025-02-19 17:26:24

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3-(Trifluoromethyl)benzaldehyde Properties

Boiling point	83-86 °C30 mm Hg(lit.)
Density	1.301 g/mL at 25 °C(lit.)
refractive index	n20/D 1.465(lit.)
Flash point	155 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Liquid
color	Clear colorless to very slightly orange
Specific Gravity	1.301
Sensitive	Air Sensitive
BRN	2327537
InChIKey	NMTUHPSKJJYGML-UHFFFAOYSA-N
CAS DataBase Reference	454-89-7(CAS DataBase Reference)
FDA UNII	AT7H4H5U3E
NIST Chemistry Reference	Benzaldehyde, 3-(trifluoromethyl)-(454-89-7)
EPA Substance Registry System	Benzaldehyde, 3-(trifluoromethyl)- (454-89-7)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS09

Signal word

Warning

Hazard statements

H315-H319-H335-H410

Precautionary statements

P261-P264-P271-P273-P302+P352-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

RIDADR

UN3082 - class 9 - PG 3 - DOT NA1993 - Environmentally hazardous substances, liquid, n.o.s. HI: all (not BR)

WGK Germany

10-23

TSCA

HazardClass

IRRITANT

HS Code

29130000

NFPA 704

	2
2		0

3-(Trifluoromethyl)benzaldehyde price More Price(38)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	196878	3-(Trifluoromethyl)benzaldehyde 97%	454-89-7	25g	$42.8	2024-03-01	Buy
Sigma-Aldrich	196878	3-(Trifluoromethyl)benzaldehyde 97%	454-89-7	5g	$61.8	2024-03-01	Buy
TCI Chemical	T1399	3-(Trifluoromethyl)benzaldehyde >95.0%(GC)	454-89-7	5g	$34	2024-03-01	Buy
TCI Chemical	T1399	3-(Trifluoromethyl)benzaldehyde >95.0%(GC)	454-89-7	25g	$98	2024-03-01	Buy
Alfa Aesar	A10463	3-(Trifluoromethyl)benzaldehyde, 97%	454-89-7	5g	$48.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
196878	25g	$42.8	Buy
196878	5g	$61.8	Buy
T1399	5g	$34	Buy
T1399	25g	$98	Buy
A10463	5g	$48.65	Buy

3-(Trifluoromethyl)benzaldehyde Chemical Properties,Uses,Production

Uses

3-(Trifluoromethyl)benzaldehyde is used as a reagent in the synthesis of 2,3-di- and 2,2,3-trisubstituted-3-methoxycarbonyl-γ-butyrolactones as potent antitumor agents. Also used as a reagent in the synthesis of novel chalcone derivatives as hypoxia-inducible factor (HIF)-1 inhibitors.

Chemical Properties

CLEAR COLOURLESS TO VERY SLIGHTLY ORANGE LIQUID

Uses

3-(Trifluoromethyl)benzaldehyde is used as a reagent in the synthesis of 2,3-di- and 2,2,3-trisubstituted-3-methoxycarbonyl-╬│-butyrolactones as potent antitumor agents. Also used as a reagent in the synthesis of novel chalcone derivatives as hypoxia-inducible factor (HIF)-1 inhibitors.

Synthesis Reference(s)

Journal of the American Chemical Society, 68, p. 426, 1946 DOI: 10.1021/ja01207a024

General Description

Aldol reaction of 3-(trifluoromethyl)benzaldehyde with hydroxyacetone in the aldolase antibody 38C2-ionic liquid system has been investigated.

3-(Trifluoromethyl)benzaldehyde synthesis

Synthesis of 3-(Trifluoromethyl)benzaldehyde from 3-(Trifluoromethyl)benzyl alcohol

3-(Trifluoromethyl)benzaldehyde Preparation Products And Raw materials

Raw materials

1,3-Diphenyl-1,1,3,3-tetramethyldisiloxane

Preparation Products

3-(3-Trifluoromethylphenyl)propionic acid 3-(Trifluoromethyl)benzoyl chloride 3-(Trifluoromethyl)benzyl bromide 3-(3-(Trifluoromethyl)phenyl)propan-1-ol 3-(Trifluoromethyl)cinnamic acid

3,3'-BIS(TRIFLUOROMETHYL)BENZOPHENONE 3-（trifluoromethyl) Cinnamaldehyde 3-(TRIFLUOROMETHYL)BENZOYL FLUORIDE 3'-(TRIFLUOROMETHYL)PROPIOPHENONE 3-(Trifluoromethyl)benzylamine

3-(TRIFLUOROMETHYL)BENZALDOXIME

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3-(Trifluoromethyl)benzaldehyde Suppliers

Global( 498)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Weibang Biotechnology Co., Ltd	+8615531157085	abby@weibangbio.com	China	8804	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-81139210 +86-18192627656	1059@dideu.com	China	3003	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-81148696 +86-15536356810	1022@dideu.com	China	3882	58
Hebei Mujin Biotechnology Co.,Ltd	+86 13288715578 +8613288715578	sales@hbmojin.com	China	12826	58
Hebei Kingfiner Technology Development Co.Ltd	+86-15532196582 +86-15373005021	lisa@kingfinertech.com	China	3007	58
Hebei Junhua Import and Export Co., LTD	+8618503288844	junhua1@hb-junhua.com	China	267	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29792	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	19906	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21632	55
Fluoropharm Co., Ltd.	+86-0571-85586753; +8613336034509	sales@fluoropharm.com	China	1376	60

Supplier	Advantage
Hebei Weibang Biotechnology Co., Ltd	58
Shaanxi Dideu Medichem Co. Ltd	58
Shaanxi Dideu Medichem Co. Ltd	58
Hebei Mujin Biotechnology Co.,Ltd	58
Hebei Kingfiner Technology Development Co.Ltd	58
Hebei Junhua Import and Export Co., LTD	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Fluoropharm Co., Ltd.	60

View Lastest Price from 3-(Trifluoromethyl)benzaldehyde manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-02-20	3-(Trifluoromethyl)benzaldehyde 454-89-7	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mujin Biotechnology Co.,Ltd
2025-02-20	3-(Trifluoromethyl)benzaldehyde 454-89-7	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mujin Biotechnology Co.,Ltd
2025-02-20	3-(Trifluoromethyl)benzaldehyde 454-89-7	US $5.00 / kg	1kg	≥99%	200mt/year	Jinan Finer Chemical Co., Ltd

3-(Trifluoromethyl)benzaldehyde
454-89-7
US $0.00 / KG
99%
Hebei Mujin Biotechnology Co.,Ltd

3-(Trifluoromethyl)benzaldehyde
454-89-7
US $0.00 / KG
99%
Hebei Mujin Biotechnology Co.,Ltd

3-(Trifluoromethyl)benzaldehyde
454-89-7
US $5.00 / kg
≥99%
Jinan Finer Chemical Co., Ltd

3-(Trifluoromethyl)benzaldehyde Spectrum

3-(Trifluoromethyl)benzaldehyde(454-89-7)MS 3-(Trifluoromethyl)benzaldehyde(454-89-7)¹HNMR 3-(Trifluoromethyl)benzaldehyde(454-89-7)¹³CNMR 3-(Trifluoromethyl)benzaldehyde(454-89-7)IR1 3-(Trifluoromethyl)benzaldehyde(454-89-7)Raman

454-89-7(3-(Trifluoromethyl)benzaldehyde)Related Search:

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m-Trifluoromethoxy benzaldehyde 3-Formylbenzotrifluoride, alpha,alpha,alpha-Trifluoro-3-tolualdehyde Alpha-Trifluoro-M-tolualdehyde 3-(TrifluoroMethyl)benzaldehyde, 97% 25GR 3-(TrifluoroMethyl)benzaldehyde, 97% 5GR 3-Formylbenzotrifluoride, alpha,alpha,alpha-Trifluoro-m-tolualdehyde 3-(three fluoroMethyl)benzeneforMaldehyde Between the three groups in benzene forMaldehyde alpha,alpha,alpha-Trifluoro-m-toluylaldehyde 3-TRIFLUORMETHYLBENZALDEHYDE 3-(TRIFLUOROMETHYL)BENZALDEHYDE A,A,A-TRIFLUORO-3-TOLUALDEHYDE A,A,A-TRIFLUORO-M-TOLUALDEHYDE alpha,alpha,alpha-Trifluoro-3-tolualdehyde ALPHA,ALPHA,ALPHA-TRIFLUORO-M-TOLUALDEHYDE BENZOTRIFLUORIDE-3-CARBALDEHYDE M-TRIFLUOROMETHYLBENZALDEHYDE 3-(trifluoromethyl)-benzaldehyd m-Tolualdehyde, alpha,alpha,alpha-trifluoro- m-Trifluoromethylbenzaldehyde 3-Trifluoromethyl Benzaldehyde 3-TRIFLUOROMETHYLBENZYLDEHYDE m-Trifluoromethylbenzaldehyde,97% à,à,à-trifluoro-m-tolualdehyde 3-(Trifluoromethyl)benzaldehyde98% A,A,A-TRIFLUORO-META-TOLUALDEHYDE ALPHA,ALPHA,ALPHA-TRIFLUORO-META-TOLUALDEHYDE m-Trifuoromethylbenzaldehyde Benzaldehyde, 3-(trifluoromethyl)- 3-(Trifluoromethyl)benzaldehyde,97% Cinacalcet Impurity 56 3-(three fluoroMethyl 3-(Trifluorzomethyl)Benzaldehyde trifluoromethylbenzaldehyde-13C6 α,α,α-Trifluoro-m-toluylaldehyde MTF-BAD α,α,α-trifluoro-3-tolualdehyde 3-(Trifluoromethyl)benzaldehyde, 10 mM in DMSO 454-89-7 455-89-7 454-89-1 454-89-71 455-89-7 C8H5F3O Carbonyl Compounds C8 ALDEHYDE Organic Building Blocks Aldehydes Building Blocks Benzotrifluoride Series Aromatic Aldehydes & Derivatives (substituted) Benzaldehyde 3-(Trifluoromethyl)benzaldehyde bc0001