ChemicalBook >> CAS DataBase List >>PKI 166 hydrochloride
PKI 166 hydrochloride
- CAS No.
- 2230253-82-2
- Chemical Name:
- PKI 166 hydrochloride
- Synonyms
- PKI 166 hydrochloride;PKI 166 hydrochloride,PKI166 hydrochloride
- CBNumber:
- CB05185856
- Molecular Formula:
- C20H19ClN4O
- Molecular Weight:
- 366.85
- MDL Number:
- MOL File:
- 2230253-82-2.mol
Last updated:2024-10-28 23:16:16
PKI 166 hydrochloride Chemical Properties,Uses,Production
Biological Activity
PKI-166 hydrochloride is a potent, selective, and orally bioactive EGFR tyrosine kinase inhibitor with IC50 of 0.7 nM.
in vivo
PKI-166 hydrochloride (100 mg/kg; po; daily; for 29 days) inhibits of pancreatic cancer growth.
| Animal Model: < /td> | Male athymic nude mice with L3.6pl cells xenograft (8-12 weeks) |
| Dosage: < /td> | 100 mg/kg |
| Administration: | Oral administration; daily; for 29 days |
| Result: | Significantly decreased median tumor volume. |
target
IC50: 0.7 nM (EGFR tyrosine kinase)
storage
Store at +4°C
PKI 166 hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
PKI 166 hydrochloride Suppliers
Global( 11)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52925 | 58 |
| Nanjing Nohon Biological Technology Co., Ltd. | 025-85767923 18512596075 | sales@nuoxibio.com | China | 1364 | 55 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6777 | 58 |
| Guangzhou Younan Technology Co., Ltd | 020-82000279 18988968278 | sales@ubiochem.com | China | 4297 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29774 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24647 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 4933 | 58 |
| United States Biological | -- | sales@advtechind.com | United States | 6075 | 58 |
View Lastest Price from PKI 166 hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-28 | PKI-166 hydrochloride
2230253-82-2
|
US $578.00 / mg | 10g | TargetMol Chemicals Inc. |
-
- PKI-166 hydrochloride
2230253-82-2
- US $578.00 / mg
- TargetMol Chemicals Inc.
PKI 166 hydrochloride
PKI 166 hydrochloride,PKI166 hydrochloride
2230253-82-2