ChemicalBook >> CAS DataBase List >>PKUMDL-LC-101-D04
PKUMDL-LC-101-D04
- CAS No.
- 2143896-83-5
- Chemical Name:
- PKUMDL-LC-101-D04
- Synonyms
- PKUMDL-LC-101-D04;GPX4-Activator-1d4;PKUMDL LC 101 D04,PKUMDL-LC-101-D-04,PKUMDLLC101D04;N-(2-Aminoethyl)-4-(3-cyclopentylthioureido)benzenesulfonamide hydrochloride;N-(2-aminoethyl)-4-[[(cyclopentylamino)thioxomethyl]amino]-benzenesulfonamide, monohydrochloride
- CBNumber:
- CB06197722
- Molecular Formula:
- C14H23ClN4O2S2
- Molecular Weight:
- 378.93
- MDL Number:
- MOL File:
- 2143896-83-5.mol
Last updated:2024-11-01 18:09:03
PKUMDL-LC-101-D04 Chemical Properties,Uses,Production
Description
PKUMDL-LC-101-D04 is an allosteric activator of glutathione peroxidase 4 (GPX4).1 It increases GPX4 activity to 150% of control levels when used at a concentration of 20 μM in a cell-free assay and at 61 μM in wild-type, but not Gpx4-/-, mouse embryonic fibroblast (MEF) extracts. PKUMDL-LC-101-D04 (200 μM) also reduces cholesterol hydroperoxide-induced MEF death.
References
1. Li, C., Deng, X., Zhang, W., et al. Novel allosteric activators for ferroptosis regulator glutathione peroxidase 4 J. Med. Chem. 62(1),266-275(2019).
PKUMDL-LC-101-D04 Preparation Products And Raw materials
Raw materials
Preparation Products
PKUMDL-LC-101-D04 Suppliers
Global( 21)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32820 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32038 | 58 |
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 | 757984502@qq.com | China | 892 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9806 | 58 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 6527 | 58 |
| Heze Development Zone chuangli Chemical Co., Ltd. | +86-530-529 6766，+86-15666160102 15666160102 | info@chuangli-chem.com | China | 889 | 55 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6777 | 58 |
| DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9410 | 58 |
| Wuxi Donghe Pharmaceutical Technology Co., Ltd. | 63313187 15358055255 | 63313187@qq.com | China | 1993 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11217 | 58 |
View Lastest Price from PKUMDL-LC-101-D04 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-01 | PKUMDL-LC-101-D04
2143896-83-5
|
US $80.00-428.00 / mg | 98.71% | 10g | TargetMol Chemicals Inc. |
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- PKUMDL-LC-101-D04
2143896-83-5
- US $80.00-428.00 / mg
- 98.71%
- TargetMol Chemicals Inc.
GPX4-Activator-1d4
PKUMDL-LC-101-D04
PKUMDL LC 101 D04,PKUMDL-LC-101-D-04,PKUMDLLC101D04
N-(2-aminoethyl)-4-[[(cyclopentylamino)thioxomethyl]amino]-benzenesulfonamide, monohydrochloride
N-(2-Aminoethyl)-4-(3-cyclopentylthioureido)benzenesulfonamide hydrochloride
2143896-83-5