Sodium dichloroacetate
- CAS No.
- 2156-56-1
- Chemical Name:
- Sodium dichloroacetate
- Synonyms
- SDA;dichloroctansodny;erlcyiuanna;sodium dichloroacet;NATRIUMDICHLORACETAT;Sodiumdichloracetate;Dichloroacetate (DCA);SODIUM DICHLOROACETATE;Dichloroacetate Sodium;Sodium dichloroacetater
- CBNumber:
- CB0695718
- Molecular Formula:
- C2H3Cl2NaO2
- Molecular Weight:
- 152.93
- MDL Number:
- MFCD00070489
- MOL File:
- 2156-56-1.mol
- MSDS File:
- SDS
Melting point | 198 °C (dec.) (lit.) |
---|---|
storage temp. | Inert atmosphere,2-8°C |
solubility | Methanol (Slightly), Water (Slightly) |
form | Powder |
color | White |
PH | 6.0 to 8.5(50g/L, 25 ℃) |
Water Solubility | soluble in cold water |
Sensitive | Moisture Sensitive |
Stability | Hygroscopic |
InChIKey | LUPNKHXLFSSUGS-UHFFFAOYSA-M |
CAS DataBase Reference | 2156-56-1(CAS DataBase Reference) |
FDA UNII | 42932X67B5 |
NCI Drug Dictionary | sodium dichloroacetate |
EPA Substance Registry System | Sodium dichloroacetate (2156-56-1) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07,GHS08 |
|||||||||
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335-H351 | |||||||||
Precautionary statements | P201-P302+P352-P305+P351+P338-P308+P313 | |||||||||
Hazard Codes | Xi,Xn | |||||||||
Risk Statements | 36/37/38-40 | |||||||||
Safety Statements | 26-37/39-36-36/37 | |||||||||
RIDADR | 2811 | |||||||||
WGK Germany | 2 | |||||||||
RTECS | AG9275000 | |||||||||
HS Code | 29154000 | |||||||||
NFPA 704 |
|
Sodium dichloroacetate price More Price(25)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 347795 | Sodium dichloroacetate 98% | 2156-56-1 | 10g | $75.8 | 2024-03-01 | Buy |
Sigma-Aldrich | 347795 | Sodium dichloroacetate 98% | 2156-56-1 | 50g | $262 | 2024-03-01 | Buy |
TCI Chemical | D1048 | Sodium Dichloroacetate >97.0%(T) | 2156-56-1 | 25g | $76 | 2024-03-01 | Buy |
TCI Chemical | D1719 | Sodium Dichloroacetate >99.0%(T) | 2156-56-1 | 10g | $54 | 2024-03-01 | Buy |
Alfa Aesar | B21827 | Sodium dichloroacetate, 97% | 2156-56-1 | 10g | $57.65 | 2024-03-01 | Buy |
Sodium dichloroacetate Chemical Properties,Uses,Production
Uses
Sodium dichloroacetate (DCA) is a mitochondrial pyruvate dehydrogenase kinase inhibitor, and is an orally absorbable small molecular compound for MELAS syndrome, and children with congenital lactic acidosis and other diseases that are treated in the clinic. Recent studies had found that DCA acts as a potential vasoprotective agent by inhibiting PDK2 and reducing coronary endarterium proliferation. Further, DCA promotes brain regeneration after cerebral ischemia, which indicates that DCA might play an important role in VD.
Chemical Properties
white powder
Uses
Sodium dichloroacetate is an inhibitor of mitochondrial pyruvate dehydrogenase kinase.
Uses
Treatment of neurologic injury (pyruvate dehydrogenase activator).
brand name
Ceresine (Cypros).
General Description
Sodium dichloroacetate is a mitochondrial pyruvate dehydrogenase kinase (PDK) inhibitor that exhibits potent anti-leukemic activity.
Biological Activity
Inhibitor of mitochondrial pyruvate dehydrogenase kinase (PDK). Shifts pyruvate metabolism from glycolysis and lactate production to glucose oxidation in the mitochondria. Induces mitochondrial-dependent apoptosis and reverses the inhibition/downregulation of K V 1.5 channels in cancer but not normal cells. Decreases tumor growth in vitro and in vivo .
storage
Desiccate at RT
Sodium dichloroacetate Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12839 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5857 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5892 | 58 |
Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-17333973358 | sales06@hbduling.cn | China | 8053 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20287 | 58 |
Hangzhou Hyper Chemicals Limited | +86-0086-57187702781 +8613675893055 | info@hyper-chem.com | China | 295 | 58 |
Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618092446649 | sarah@tnjone.com | China | 1143 | 58 |
Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3002 | 58 |
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | +86-15350851019 +86-15383190639 | admin@86-ss.com | China | 1000 | 58 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
Related articles
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- Dec 30,2019
View Lastest Price from Sodium dichloroacetate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-25 | Sodium Dichloroacetate
2156-56-1
|
US $99.00-35.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co.,Ltd | ||
2024-11-25 | Sodium dichloroacetate
2156-56-1
|
US $100.00-75.00 / kg | 1kg | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | ||
2024-11-17 | Sodium dichloroacetate
2156-56-1
|
US $45.00 / mg | 99.87% | 10g | TargetMol Chemicals Inc. |
- Sodium Dichloroacetate
2156-56-1
- US $99.00-35.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
- Sodium dichloroacetate
2156-56-1
- US $100.00-75.00 / kg
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
- Sodium dichloroacetate
2156-56-1
- US $45.00 / mg
- 99.87%
- TargetMol Chemicals Inc.