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Sodium dichloroacetate

CAS No.
2156-56-1
Chemical Name:
Sodium dichloroacetate
Synonyms
SDA;dichloroctansodny;erlcyiuanna;sodium dichloroacet;NATRIUMDICHLORACETAT;Sodiumdichloracetate;Dichloroacetate (DCA);SODIUM DICHLOROACETATE;Dichloroacetate Sodium;Sodium dichloroacetater
CBNumber:
CB0695718
Molecular Formula:
C2H3Cl2NaO2
Molecular Weight:
152.93
MDL Number:
MFCD00070489
MOL File:
2156-56-1.mol
MSDS File:
SDS
Last updated:2024-11-17 16:00:36

Sodium dichloroacetate Properties

Melting point 198 °C (dec.) (lit.)
storage temp. Inert atmosphere,2-8°C
solubility Methanol (Slightly), Water (Slightly)
form Powder
color White
PH 6.0 to 8.5(50g/L, 25 ℃)
Water Solubility soluble in cold water
Sensitive Moisture Sensitive
Stability Hygroscopic
InChIKey LUPNKHXLFSSUGS-UHFFFAOYSA-M
CAS DataBase Reference 2156-56-1(CAS DataBase Reference)
FDA UNII 42932X67B5
NCI Drug Dictionary sodium dichloroacetate
EPA Substance Registry System Sodium dichloroacetate (2156-56-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Warning
Hazard statements  H315-H319-H335-H351
Precautionary statements  P201-P302+P352-P305+P351+P338-P308+P313
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-40
Safety Statements  26-37/39-36-36/37
RIDADR  2811
WGK Germany  2
RTECS  AG9275000
HS Code  29154000
NFPA 704
0
2 0

Sodium dichloroacetate price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 347795 Sodium dichloroacetate 98% 2156-56-1 10g $75.8 2024-03-01 Buy
Sigma-Aldrich 347795 Sodium dichloroacetate 98% 2156-56-1 50g $262 2024-03-01 Buy
TCI Chemical D1048 Sodium Dichloroacetate >97.0%(T) 2156-56-1 25g $76 2024-03-01 Buy
TCI Chemical D1719 Sodium Dichloroacetate >99.0%(T) 2156-56-1 10g $54 2024-03-01 Buy
Alfa Aesar B21827 Sodium dichloroacetate, 97% 2156-56-1 10g $57.65 2024-03-01 Buy
Product number Packaging Price Buy
347795 10g $75.8 Buy
347795 50g $262 Buy
D1048 25g $76 Buy
D1719 10g $54 Buy
B21827 10g $57.65 Buy

Sodium dichloroacetate Chemical Properties,Uses,Production

Uses

Sodium dichloroacetate (DCA) is a mitochondrial pyruvate dehydrogenase kinase inhibitor, and is an orally absorbable small molecular compound for MELAS syndrome, and children with congenital lactic acidosis and other diseases that are treated in the clinic. Recent studies had found that DCA acts as a potential vasoprotective agent by inhibiting PDK2 and reducing coronary endarterium proliferation. Further, DCA promotes brain regeneration after cerebral ischemia, which indicates that DCA might play an important role in VD.

Chemical Properties

white powder

Uses

Sodium dichloroacetate is an inhibitor of mitochondrial pyruvate dehydrogenase kinase.

Uses

Treatment of neurologic injury (pyruvate dehydrogenase activator).

brand name

Ceresine (Cypros).

General Description

Sodium dichloroacetate is a mitochondrial pyruvate dehydrogenase kinase (PDK) inhibitor that exhibits potent anti-leukemic activity.

Biological Activity

Inhibitor of mitochondrial pyruvate dehydrogenase kinase (PDK). Shifts pyruvate metabolism from glycolysis and lactate production to glucose oxidation in the mitochondria. Induces mitochondrial-dependent apoptosis and reverses the inhibition/downregulation of K V 1.5 channels in cancer but not normal cells. Decreases tumor growth in vitro and in vivo .

storage

Desiccate at RT

79-43-6
2156-56-1
Synthesis of Sodium dichloroacetate from Dichloroacetic acid

Sodium dichloroacetate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 323)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd
+86 13288715578 +8613288715578 sales@hbmojin.com China 12839 58
Hebei Yanxi Chemical Co., Ltd.
+8617531190177 peter@yan-xi.com China 5857 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325 sales1@chuanghaibio.com China 5892 58
Hebei Fengjia New Material Co., Ltd
+86-0311-87836622 +86-17333973358 sales06@hbduling.cn China 8053 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20287 58
Hangzhou Hyper Chemicals Limited
+86-0086-57187702781 +8613675893055 info@hyper-chem.com China 295 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618092446649 sarah@tnjone.com China 1143 58
Hebei Zhuanglai Chemical Trading Co.,Ltd
+8613343047651 admin@zlchemi.com China 3002 58
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
+86-15350851019 +86-15383190639 admin@86-ss.com China 1000 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29791 60

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View Lastest Price from Sodium dichloroacetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Sodium Dichloroacetate pictures 2024-11-25 Sodium Dichloroacetate
2156-56-1
US $99.00-35.00 / kg 1kg 99% 20ton Hebei Zhuanglai Chemical Trading Co.,Ltd
Sodium dichloroacetate pictures 2024-11-25 Sodium dichloroacetate
2156-56-1
US $100.00-75.00 / kg 1kg 99% 5000 HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Sodium dichloroacetate pictures 2024-11-17 Sodium dichloroacetate
2156-56-1
US $45.00 / mg 99.87% 10g TargetMol Chemicals Inc.
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