Hydroxyacetone
- CAS No.
- 116-09-6
- Chemical Name:
- Hydroxyacetone
- Synonyms
- 2-Propanone, 1-hydroxy-;1-hydroxypropan-2-one;ACETOL;1-HYDROXY-2-PROPANONE;1-Hydroxyacetone;1-hydroxy-propan-2-one;2-oxopropanol;Acetomethanol;Hydroxyaceton;Hydroxypropanone
- CBNumber:
- CB0714802
- Molecular Formula:
- C3H6O2
Lewis structure
- Molecular Weight:
- 74.08
- MDL Number:
- MFCD00004669
- MOL File:
- 116-09-6.mol
- MSDS File:
- SDS
Melting point | -17 °C (lit.) |
---|---|
Boiling point | 145-146 °C (lit.) |
Density | 1.082 g/mL at 25 °C (lit.) |
vapor pressure | 9.01hPa at 25℃ |
FEMA | 4462 | HYDROXYACETONE |
refractive index |
n |
Flash point | 133 °F |
storage temp. | 2-8°C |
solubility | water: miscible |
pka | 13.14±0.10(Predicted) |
form | clear liquid |
color | Colorless liquid |
Specific Gravity | 1.090 (20/4℃) |
Odor | at 10.00 % in dipropylene glycol. pungent sweet caramellic ethereal |
Odor Type | caramellic |
Water Solubility | Miscible with water, alcohol and ether. |
Sensitive | Hygroscopic |
Merck | 14,65 |
JECFA Number | 1945 |
BRN | 605368 |
Stability | Stable. Flammable. Incompatible with strong oxidizing agents, strong acids. Protect from moisture - hygroscopic. |
InChIKey | XLSMFKSTNGKWQX-UHFFFAOYSA-N |
LogP | 0.3 at 25℃ |
Substances Added to Food (formerly EAFUS) | HYDROXYACETONE |
CAS DataBase Reference | 116-09-6(CAS DataBase Reference) |
EWG's Food Scores | 1 |
FDA UNII | 7I7YM0835W |
NIST Chemistry Reference | 2-Propanone, 1-hydroxy-(116-09-6) |
EPA Substance Registry System | 1-Hydroxyacetone (116-09-6) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS02 |
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Signal word | Warning | |||||||||
Hazard statements | H226 | |||||||||
Precautionary statements | P210-P233-P240-P241-P242-P243 | |||||||||
Risk Statements | 2017/10/16 | |||||||||
Safety Statements | 23-24/25-5 | |||||||||
RIDADR | UN 1224 3/PG 3 | |||||||||
WGK Germany | 1 | |||||||||
RTECS | UC2800000 | |||||||||
TSCA | Yes | |||||||||
HazardClass | 3 | |||||||||
PackingGroup | III | |||||||||
HS Code | 29144090 | |||||||||
Toxicity | mmo-sat 500 mg/plate ABCHA6 47,2461,83 | |||||||||
NFPA 704 |
|
Hydroxyacetone price More Price(24)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 138185 | Hydroxyacetone contains ≤500ppm sodium carbonate as stabilizer, technical grade, 90% | 116-09-6 | 5g | $41 | 2024-03-01 | Buy |
Sigma-Aldrich | 138185 | Hydroxyacetone contains ≤500ppm sodium carbonate as stabilizer, technical grade, 90% | 116-09-6 | 100g | $44.3 | 2024-03-01 | Buy |
TCI Chemical | H0388 | Hydroxyacetone >80.0%(GC) | 116-09-6 | 25mL | $34 | 2024-03-01 | Buy |
TCI Chemical | H0388 | Hydroxyacetone >80.0%(GC) | 116-09-6 | 100mL | $58 | 2024-03-01 | Buy |
Alfa Aesar | L15008 | Hydroxyacetone, 95% | 116-09-6 | 100g | $43.7 | 2024-03-01 | Buy |
Hydroxyacetone Chemical Properties,Uses,Production
Chemical Properties
colourless to yellow liquid
Uses
Reagent in organic synthesis; protecting group for the synthesis of peptides.
Uses
Hydroxyacetone is a chemical reagent used in various organic chemical reactions. It is a component of the Mannich reaction, amino acid caalyzes direct asymmetric aldol reactions. In the pharmaceutical setting, this compound is used in the synthesis of imidazoles acting as potent and orally active antihypertensive agents.
Uses
Hydroxyacetone is used as a reagent in organic chemical reactions. It also serves as a component for Mannich reaction and aldol reactions. It is also used in the syntheses of 2-oxo-propionaldehyde, imidazoles, polyols, acrolein, dyes and skin tanning agents. It yields (R)-1,2-propanediol upon reduction of hydroxyacetone in the presence of a microbial cell catalyst.
Definition
ChEBI: A propanone that is acetone in which one of the methyl hydrogens is replaced by a hydroxy group.
General Description
Hydroxyacetone (Acetol) is important for the manufacture of polyols, acrolein, dyes and skin tanning agents. It undergoes asymmetric reduction to yield (R)-1,2-propanediol in the presence of microbial cell catalyst.
Safety Profile
Moderately toxic by ingestion. Mutation data reported. An allergen. Implicated in aplastic anemia. A 10 gram dose may be fatal to an adult. skin contact, inhalation, or ingestion can cause asthma, sneezing, irritation of eyes and nose, hives, and eczema. Combustible when exposed to heat or flame. When heated to decomposition it emits acrid smoke and fumes.
Synthesis
Hydroxyacetone is produced from Bromoacetone plus sodium formate, followed by Methanol hydrolysis of the formed ester. Or by biochemical synthesis from Propylene glycol with sorbose bacterium.
Hydroxyacetone Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12495 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5895 | 58 |
JINING XINHE CHEMICAL CO., LTD | +8615318402391 | sales@xinhepharma.com | China | 808 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18628 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21663 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8820 | 58 |
Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
View Lastest Price from Hydroxyacetone manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-29 | Hydroxyacetone
116-09-6
|
US $10.70-10.70 / kg | 10kg | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | ||
2024-07-16 | Hydroxyacetone
116-09-6
|
US $0.00-0.00 / kg | 1kg | 98% | 10ton | JINING XINHE CHEMICAL CO., LTD | ||
2023-08-14 | Hydroxyacetone
116-09-6
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd |
- Hydroxyacetone
116-09-6
- US $10.70-10.70 / kg
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
- Hydroxyacetone
116-09-6
- US $0.00-0.00 / kg
- 98%
- JINING XINHE CHEMICAL CO., LTD
- Hydroxyacetone
116-09-6
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd