ChemicalBook >> CAS DataBase List >>(+)-ALPHA-DIHYDROTETRABENAZINE
(+)-ALPHA-DIHYDROTETRABENAZINE
- CAS No.
- 3466-75-9
- Chemical Name:
- (+)-ALPHA-DIHYDROTETRABENAZINE
- Synonyms
- DTBZ;DIHYDROTETRABENAZINE;Hydroxy Tetrabenazine;(+)-ALPHA-DIHYDROTETRABEZINE;(+)-ALPHA-DIHYDROTETRABENAZINE;(+)-ALPHA-DIHYDROTETRABENAZINE;Hydroxy Tetrabenazine - Mixture of cis and trans Isomers;2H-Benzo[a]quinolizin-2-ol, 1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-;2H-BENZO[A]QUINOLIZINE-2-OL, 1,3,4,6,7,11B-HEXAHYDRO-3-ISOBUTYL-9,10-DIMETHOXY-;9,10-dimethoxy-3-(2-methylpropyl)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-ol
- CBNumber:
- CB0716932
- Molecular Formula:
- C19H29NO3
- Molecular Weight:
- 319.44
- MDL Number:
- MFCD20275194
- MOL File:
- 3466-75-9.mol
Last updated:2023-06-08 09:03:09
| Boiling point | 457.8±45.0 °C(Predicted) |
|---|---|
| Density | 1.13±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Chloroform: soluble; Methanol: soluble |
| form | A solid |
| pka | 14.75±0.40(Predicted) |
| CAS DataBase Reference | 3466-75-9 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| NFPA 704 |
|
(+)-ALPHA-DIHYDROTETRABENAZINE price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 27182 | Dihydrotetrabenazine | 3466-75-9 | 500μg | $121 | 2024-03-01 | Buy |
| Cayman Chemical | 27182 | Dihydrotetrabenazine | 3466-75-9 | 1mg | $230 | 2024-03-01 | Buy |
| TRC | H627630 | HydroxyTetrabenazine-MixtureofcisandtransIsomers | 3466-75-9 | 100mg | $175 | 2021-12-16 | Buy |
| AK Scientific | Z3455 | trans-Dihydrotetrabenazine | 3466-75-9 | 1mg | $353 | 2021-12-16 | Buy |
| Chemtos | T-6836 | 2-alpha-DihydrotetrabenazineLabeledd7 | 3466-75-9 | 10mg | $2375 | 2021-12-16 | Buy |
(+)-ALPHA-DIHYDROTETRABENAZINE Chemical Properties,Uses,Production
Description
Dihydrotetrabenazine is an active metabolite of the vesicular monoamine transporter 2 (VMAT2) inhibitor tetrabenazine that is generated by hepatic carbonyl reductases. Dihydrotetrabenazine binds to mouse pons medulla, hypothalamus, and striatum (Kds = 2.72, 2.28, and 2.4 nM, respectively) and inhibits synaptic vesicular serotonin (5-HT) uptake (IC50s = 2.2, 2.8, and 2.3 nM, respectively). It also binds to human caudate nucleus, hippocampus, and substantia nigra pars compacta (Kds = 2.9, 2.5, and 2.8 nM, respectively). Dihydrotetrabenazine stereoisomers bind to VMAT2 in rat striatum.
Chemical Properties
Colourless solid
Definition
ChEBI: B-Dihydrotetrabenazine is a member of isoquinolines.
(+)-ALPHA-DIHYDROTETRABENAZINE Preparation Products And Raw materials
Raw materials
Preparation Products
(+)-ALPHA-DIHYDROTETRABENAZINE Suppliers
Global( 27)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20324 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2923 | 55 | |
| Daicel Chiral Technologies (China)CO.,LTD | 021-50460086-9 15921403865 | han_yajun@dctc.daicel.com | China | 6943 | 65 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
| ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 | sales@chem-strong.com | China | 18018 | 56 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9926 | 65 |
| Shenzhen SUNGENING Bio-Medical Co., Ltd. | 0755-28967200 13631290199 | wxf@sungening.com | China | 9592 | 60 |
| SHANGHAI FDC-CHEMICAL CO.,LTD | 021-61469567 18521078705 | sales@fdc-chemical.com | China | 19969 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
3466-75-9((+)-ALPHA-DIHYDROTETRABENAZINE)Related Search:
(+)-ALPHA-DIHYDROTETRABENAZINE
2H-BENZO[A]QUINOLIZINE-2-OL, 1,3,4,6,7,11B-HEXAHYDRO-3-ISOBUTYL-9,10-DIMETHOXY-
DIHYDROTETRABENAZINE
DTBZ
2H-Benzo[a]quinolizin-2-ol, 1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-
1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol
(+)-ALPHA-DIHYDROTETRABEZINE
Hydroxy Tetrabenazine
9,10-dimethoxy-3-(2-methylpropyl)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-ol
Hydroxy Tetrabenazine - Mixture of cis and trans Isomers
(+)-ALPHA-DIHYDROTETRABENAZINE
2H-Benzo[a]quinolizin-2-ol, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-
3466-75-9