CNQX
- CAS No.
- 115066-14-3
- Chemical Name:
- CNQX
- Synonyms
- CNQX;CNOX;FG-9065;CNQX 2NA;CNQX DISODIUM;CNQX DISODIUM SALT;CNQX disodium salt hydrate;CNQX DISODIUM KAINATE/AMPA RECEPTOR;CNQX (FG-9065) (6-CYANO-7-NITROQUINO;6-Nitro-7-cyanoquinoxaline-2,3-dione
- CBNumber:
- CB0728641
- Molecular Formula:
- C9H4N4O4
- Molecular Weight:
- 232.15
- MDL Number:
- MFCD00069232
- MOL File:
- 115066-14-3.mol
- MSDS File:
- SDS
Melting point | 300 °C |
---|---|
Boiling point | 374.31°C (rough estimate) |
Density | 1.5507 (rough estimate) |
refractive index | 1.6590 (estimate) |
RTECS | VD1520000 |
storage temp. | protect from light |
solubility | H2O: 10 mg/mL |
form | solid |
pka | 8.16±0.20(Predicted) |
color | orange to red |
Stability | Store Tightly Sealed at RT |
CAS DataBase Reference | 115066-14-3(CAS DataBase Reference) |
FDA UNII | 6OTE87SCCW |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H302-H315-H319-H335 | |||||||||
Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
Hazard Codes | Xi | |||||||||
Safety Statements | 22-24/25 | |||||||||
WGK Germany | 3 | |||||||||
HS Code | 29335990 | |||||||||
NFPA 704 |
|
CNQX price More Price(47)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | C127 | CNQX ≥98% (HPLC), solid | 115066-14-3 | 5mg | $162 | 2024-03-01 | Buy |
Sigma-Aldrich | C127 | CNQX ≥98% (HPLC), solid | 115066-14-3 | 25mg | $546 | 2024-03-01 | Buy |
Sigma-Aldrich | 5.04914 | CNQX - CAS 115066-14-3 - Calbiochem | 115066-14-3 | 10mg | $176 | 2024-03-01 | Buy |
Alfa Aesar | J63472 | 6-Cyano-7-nitro-1,4-dihydroquinoxaline-2,3-dione, 98% | 115066-14-3 | 10mg | $133.65 | 2024-03-01 | Buy |
Alfa Aesar | J63472 | 6-Cyano-7-nitro-1,4-dihydroquinoxaline-2,3-dione, 98% | 115066-14-3 | 25mg | $349.65 | 2024-03-01 | Buy |
CNQX Chemical Properties,Uses,Production
Chemical Properties
Pale Yellow Solid
Uses
CNQX disodium salt hydrate has been used as:
- as a competitive non-NMDA receptor antagonist and competitive AMPA/kainate receptor antagonist in neuronal cultures(110)
- as a glutamatergic blockers for measuring inhibitory postsynaptic currents in projection neurons(111)
- as a AMPA glutamate receptor antagonist prefrontal cortex neurons(112)
Uses
A potent, competitive kainate/quisqualate (non-NMDA) receptor antagonist. IC50 of tritiated ligands to rat cortical membranes by CNQX: AMPA, Kainate and CPP are 0.3mM, 1.5mM, and 25mM, respectively
Uses
CNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively, versus IC50 = 25 μM for NMDA receptors). This compound has been used to specifically target AMPA and kainate receptor responses and thus differentiate from that of NMDA receptors.
Definition
ChEBI: 6-Cyano-7-nitroquinoxaline-2,3-dione is a quinoxaline derivative.
Biological Activity
Potent AMPA/kainate receptor antagonist. Also antagonist at glycine modulatory site on NMDA receptor complex.
Biochem/physiol Actions
Potent, competitive AMPA/kainate glutamate receptor antagonist.
storage
Room temperature
CNQX Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 13256 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
AFINE CHEMICALS LIMITED | +86-0571-85134551 | info@afinechem.com | China | 15395 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10522 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25363 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33350 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32360 | 55 |
View Lastest Price from CNQX manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2021-08-12 | 6-CYANO-7-NITROQUINOXALINE-2,3-DIONE
115066-14-3
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
- 6-CYANO-7-NITROQUINOXALINE-2,3-DIONE
115066-14-3
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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