1-Methyl-3-nitro-1-nitrosoguanidine
- CAS No.
- 70-25-7
- Chemical Name:
- 1-Methyl-3-nitro-1-nitrosoguanidine
- Synonyms
- MNNG;Methylnitronitrosoguanidine;MNG;1-methyl-3-nitro-1-nitroso-guanidin;N-methyl-N'-nitro-N-nitrosoguanidine;TE85;TE-85;NA 1325;nsc9369;TE 85.T
- CBNumber:
- CB0730037
- Molecular Formula:
- C2H5N5O3
- Molecular Weight:
- 147.09
- MDL Number:
- MFCD00007034
- MOL File:
- 70-25-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 118°C (dec.) |
|---|---|
| Boiling point | 267.16°C (rough estimate) |
| Density | 1.7979 (rough estimate) |
| refractive index | 1.6410 (estimate) |
| storage temp. | 0-6°C |
| solubility | almost transparency in hot Methanol |
| form | powder to crystal |
| pka | 3.09±0.50(Predicted) |
| color | Light yellow to Brown |
| Water Solubility | Reacts violently |
| Merck | 14,6103 |
| Henry's Law Constant | 8.2×106 mol/(m3Pa) at 25℃, HSDB (2015) |
| Stability | Unstable. Reacts violently with water. May detonate under impact. Heat, light and moisture sensitive. May explode if stored in sealed ampules. Highly flammable. Incompatible with aqueous solutions, acids, bases, oxidizing agents, reducing agents. Alkaline hydrolysis releases toxic and explosive gases. |
| InChIKey | VZUNGTLZRAYYDE-UHFFFAOYSA-N |
| CAS DataBase Reference | 70-25-7(CAS DataBase Reference) |
| EWG's Food Scores | 2 |
| FDA UNII | 12H3O2UGSF |
| Proposition 65 List | N-Methyl-N'-nitro-N-nitrosoguanidine |
| IARC | 2A (Vol. 4, Sup 7) 1987 |
| NIST Chemistry Reference | Guanidine, n-methyl-n'-nitro-n-nitroso-(70-25-7) |
| EPA Substance Registry System | N-Methyl-N'-nitro-N-nitrosoguanidine (70-25-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |      GHS02,GHS06,GHS07,GHS08,GHS09 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H228-H301-H315-H319-H332-H350-H411 | |||||||||
| Precautionary statements | P201-P202-P210-P240-P241-P261-P264-P270-P271-P273-P280-P301+P310+P330-P302+P352+P332+P313+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P308+P313-P391-P405-P501 | |||||||||
| Hazard Codes | T;N,N,T | |||||||||
| Risk Statements | 45-20-36/38-51/53 | |||||||||
| Safety Statements | 53-45-61 | |||||||||
| RIDADR | 2926 | |||||||||
| RTECS | MF4200000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 2925290090 | |||||||||
| HazardClass | 4.1 | |||||||||
| PackingGroup | II | |||||||||
| Hazardous Substances Data | 70-25-7(Hazardous Substances Data) | |||||||||
| Toxicity | LD50 oral in rat: 90mg/kg | |||||||||
| NFPA 704 |
|
1-Methyl-3-nitro-1-nitrosoguanidine price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | M0527 | 1-Methyl-3-nitro-1-nitrosoguanidine (wetted with ca. 50% Water) (unit weight on dry weight basis) >95.0%(T) | 70-25-7 | 5g | $89 | 2021-12-16 | Buy |
| TCI Chemical | M0527 | 1-Methyl-3-nitro-1-nitrosoguanidine (wetted with ca. 50% Water) (unit weight on dry weight basis) >95.0%(T) | 70-25-7 | 25g | $313 | 2021-12-16 | Buy |
| TRC | TRC-N493990-5G | N'-Nitro-N-nitroso-N-methylguanidine (Stabilized with Water) >95%(HPLC) | 70-25-7 | 5g | $407 | 2026-06-03 | Buy |
| TRC | TRC-N493990-1G | N'-Nitro-N-nitroso-N-methylguanidine (Stabilized with Water) >95%(HPLC) | 70-25-7 | 1g | $149 | 2026-06-03 | Buy |
| TRC | TRC-N493990-100MG | N'-Nitro-N-nitroso-N-methylguanidine (Stabilized with Water) >95%(HPLC) | 70-25-7 | 100mg | $102 | 2026-06-03 | Buy |
1-Methyl-3-nitro-1-nitrosoguanidine Chemical Properties, Uses, Production
Chemical Properties
yellow to pink crystals
Uses
Experimentally as carcinogen and mutagen. Formerly in preparation of diazomethane.
Uses
A DNA-damaging agent, used as a positive control in SHE cell transformation assays.
Production Methods
MNNG is one of the first chemical mutagens and is a stabilized form of methylnitrosoguanidine, which has not been isolated. It does not occur in nature, and human exposure to it is limited to laboratories.
Definition
ChEBI: An N-nitroguanidine compound having nitroso and methyl substituents at the N'-position
General Description
A yellow powder. Melting point 244°F. Decomposes above 212°F. A suspected carcinogen. Extremely hazardous as a mutagen. Avoid skin contact and inhalation of of vapors. Usually stored frozen (below 32°F) in polyethylene bottles that are tightly closed and contained in a metal can. May decomposed during prolonged storage and develop sufficient pressure in a closed container to explode. Keep away from heat, sparks, and open flame.
Air & Water Reactions
Highly flammable. Reacts violently with water .
Reactivity Profile
1-Methyl-3-nitro-1-nitrosoguanidine will detonate under high impact. 1-Methyl-3-nitro-1-nitrosoguanidine is sensitive to heat. A sample has exploded when melted in a sealed capillary tube. Incompatible with acids, bases, oxidizing agents and reducing agents. Reacts with bases to release highly toxic, irritating and explosive gases. Reacts slowly with acids to release nitrous acid. Reacts with various nucleophiles, especially amines and thiols. Reacts with aqueous potassium hydroxide to form a highly reactive compound. The crude product from aqueous nitrosation is pyrophoric but recrystallized material is stable .
Health Hazard
Fire may produce irritating and/or toxic gases. Contact may cause burns to skin and eyes. Contact with molten substance may cause severe burns to skin and eyes. Runoff from fire control may cause pollution.
Fire Hazard
Flammable/combustible material. May be ignited by friction, heat, sparks or flames. Some may burn rapidly with flare burning effect. Powders, dusts, shavings, borings, turnings or cuttings may explode or burn with explosive violence. Substance may be transported in a molten form at a temperature that may be above its flash point. May re-ignite after fire is extinguished.
Safety Profile
Confirmed carcinogen with experimental carcinogenic, tumorigenic, and teratogenic data. Poison by ingestion, intraperitoneal, and intravenous routes. Moderately toxic by subcutaneous route. Experimental reproductive effects. Human mutation data reported. An explosive sensitive to heat or impact. Flammable when exposed to heat or flame; can react vigorously with oxidizing materials. When heated to decomposition it emits very toxic fumes of NOx.
Carcinogenicity
N-Methyl-N-nitro-N-nitrosoguanidine (MNNG) is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
1-Methyl-3-nitro-1-nitrosoguanidine Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Yantai ShengKailun Chemical Technology Co., Ltd. | 13356901049 | 3119594100@qq.com | China | 7964 | 55 |
| Rhawn Reagent | 400-1332688 18019345275 | amy@rhawn.cn | China | 1437 | 58 |
| Yantai Boyun Biological Technology Co. Ltd | 13793517650 13793517650 | 2767277144@qq.com | China | 2856 | 58 |
| Yantai Sheng Kai Lun Biological Products Co. , Ltd. | 13356901049 | mark@sklnchem.cn | China | 7947 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | 021-50182298 021-50180596 | sales@boylechem.com | China | 2202 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9409 | 55 |
View Latest Price from 1-Methyl-3-nitro-1-nitrosoguanidine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-11-11 | 1-Methyl-3-nitro-1-nitrosoguanidine
70-25-7
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2026-07-01 | 1-Methyl-3-nitro-1-nitrosoguanidine
70-25-7
|
1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2021-08-12 | 1-Methyl-3-nitro-1-nitrosoguanidine
70-25-7
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 1-Methyl-3-nitro-1-nitrosoguanidine
70-25-7
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- 1-Methyl-3-nitro-1-nitrosoguanidine
70-25-7
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- 1-Methyl-3-nitro-1-nitrosoguanidine
70-25-7
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
