1-Methyl-3-nitro-1-nitrosoguanidine

1-Methyl-3-nitro-1-nitrosoguanidine Properties

Melting point	118°C (dec.)
Boiling point	267.16°C (rough estimate)
Density	1.7979 (rough estimate)
refractive index	1.6410 (estimate)
storage temp.	0-6°C
solubility	almost transparency in hot Methanol
form	powder to crystal
pka	3.09±0.50(Predicted)
color	Light yellow to Brown
Water Solubility	Reacts violently
Merck	14,6103
Stability	Unstable. Reacts violently with water. May detonate under impact. Heat, light and moisture sensitive. May explode if stored in sealed ampules. Highly flammable. Incompatible with aqueous solutions, acids, bases, oxidizing agents, reducing agents. Alkaline hydrolysis releases toxic and explosive gases.
InChIKey	VZUNGTLZRAYYDE-UHFFFAOYSA-N
CAS DataBase Reference	70-25-7(CAS DataBase Reference)
EWG's Food Scores	2
FDA UNII	12H3O2UGSF
Proposition 65 List	N-Methyl-N'-nitro-N-nitrosoguanidine
IARC	2A (Vol. 4, Sup 7) 1987
NIST Chemistry Reference	Guanidine, n-methyl-n'-nitro-n-nitroso-(70-25-7)
EPA Substance Registry System	N-Methyl-N'-nitro-N-nitrosoguanidine (70-25-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS06,GHS07,GHS08,GHS09

Signal word

Danger

Hazard statements

H228-H301-H315-H319-H332-H350-H411

Precautionary statements

P201-P202-P210-P240-P241-P261-P264-P270-P271-P273-P280-P301+P310+P330-P302+P352+P332+P313+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P308+P313-P391-P405-P501

Hazard Codes

T;N,N,T

Risk Statements

45-20-36/38-51/53

Safety Statements

53-45-61

RIDADR

2926

RTECS

MF4200000

HS Code

2925.29.9000

HazardClass

4.1

PackingGroup

II

Toxicity

LD50 oral in rat: 90mg/kg

NFPA 704

	2
2		0

1-Methyl-3-nitro-1-nitrosoguanidine price More Price(7)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	M0527	1-Methyl-3-nitro-1-nitrosoguanidine (wetted with ca. 50% Water) (unit weight on dry weight basis) >95.0%(T)	70-25-7	5g	$89	2021-12-16	Buy
TCI Chemical	M0527	1-Methyl-3-nitro-1-nitrosoguanidine (wetted with ca. 50% Water) (unit weight on dry weight basis) >95.0%(T)	70-25-7	25g	$313	2021-12-16	Buy
TRC	N493990	N’-Nitro-N-nitroso-N-methylguanidine(StabilizedwithWater)	70-25-7	100mg	$45	2021-12-16	Buy
American Custom Chemicals Corporation	NUC0003097	N-METHYL-N'-NITRO-N-NITROSOGUANIDINE 95.00%	70-25-7	100MG	$721.88	2021-12-16	Buy
Matrix Scientific	168011	1-Methyl-3-nitro-1-nitrosoguanidine	70-25-7	25g	$792	2021-12-16	Buy

Product number	Packaging	Price	Buy
M0527	5g	$89	Buy
M0527	25g	$313	Buy
N493990	100mg	$45	Buy
NUC0003097	100MG	$721.88	Buy
168011	25g	$792	Buy

1-Methyl-3-nitro-1-nitrosoguanidine Chemical Properties,Uses,Production

Chemical Properties

yellow to pink crystals

Uses

Experimentally as carcinogen and mutagen. Formerly in preparation of diazomethane.

Uses

A DNA-damaging agent, used as a positive control in SHE cell transformation assays.

Production Methods

MNNG is one of the first chemical mutagens and is a stabilized form of methylnitrosoguanidine, which has not been isolated. It does not occur in nature, and human exposure to it is limited to laboratories.

Definition

ChEBI: An N-nitroguanidine compound having nitroso and methyl substituents at the N'-position

General Description

A yellow powder. Melting point 244°F. Decomposes above 212°F. A suspected carcinogen. Extremely hazardous as a mutagen. Avoid skin contact and inhalation of of vapors. Usually stored frozen (below 32°F) in polyethylene bottles that are tightly closed and contained in a metal can. May decomposed during prolonged storage and develop sufficient pressure in a closed container to explode. Keep away from heat, sparks, and open flame.

Air & Water Reactions

Highly flammable. Reacts violently with water .

Reactivity Profile

1-Methyl-3-nitro-1-nitrosoguanidine will detonate under high impact. 1-Methyl-3-nitro-1-nitrosoguanidine is sensitive to heat. A sample has exploded when melted in a sealed capillary tube. Incompatible with acids, bases, oxidizing agents and reducing agents. Reacts with bases to release highly toxic, irritating and explosive gases. Reacts slowly with acids to release nitrous acid. Reacts with various nucleophiles, especially amines and thiols. Reacts with aqueous potassium hydroxide to form a highly reactive compound. The crude product from aqueous nitrosation is pyrophoric but recrystallized material is stable .

Health Hazard

Fire may produce irritating and/or toxic gases. Contact may cause burns to skin and eyes. Contact with molten substance may cause severe burns to skin and eyes. Runoff from fire control may cause pollution.

Fire Hazard

Flammable/combustible material. May be ignited by friction, heat, sparks or flames. Some may burn rapidly with flare burning effect. Powders, dusts, shavings, borings, turnings or cuttings may explode or burn with explosive violence. Substance may be transported in a molten form at a temperature that may be above its flash point. May re-ignite after fire is extinguished.

Safety Profile

Confirmed carcinogen with experimental carcinogenic, tumorigenic, and teratogenic data. Poison by ingestion, intraperitoneal, and intravenous routes. Moderately toxic by subcutaneous route. Experimental reproductive effects. Human mutation data reported. An explosive sensitive to heat or impact. Flammable when exposed to heat or flame; can react vigorously with oxidizing materials. When heated to decomposition it emits very toxic fumes of NOx.

Carcinogenicity

N-Methyl-N-nitro-N-nitrosoguanidine (MNNG) is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

1-Methyl-3-nitro-1-nitrosoguanidine synthesis

Synthesis of 1-Methyl-3-nitro-1-nitrosoguanidine from 1-Methyl-3-nitroguanidine

1-Methyl-3-nitro-1-nitrosoguanidine Preparation Products And Raw materials

Raw materials

Nitroguanidine Ethanol Methylamine Sodium nitrite 2-Methyl-2-thiopseudourea sulfate

1-Methyl-3-nitroguanidine Nitric acid Methanol 1-Butanol Cyanamide

Sulfuric acid

1of3

Preparation Products

3-METHOXY-2-CYCLOHEXEN-1-ONE

1-Methyl-3-nitro-1-nitrosoguanidine Suppliers

Global( 173)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29791	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21634	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29884	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49374	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	13505	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10319	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34553	58
HONG KONG IPURE BIOLOGY CO.,LIMITED	86 18062405514 18062405514	ada@ipurechemical.com	CHINA	3461	58
Wuhan Monad Medicine Tech Co.,LTD	02768782018 18771942761	sales01@whmonad.com	CHINA	979	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Zhengzhou Alfa Chemical Co.,Ltd	58
Hubei Ipure Biology Co., Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
HONG KONG IPURE BIOLOGY CO.,LIMITED	58
Wuhan Monad Medicine Tech Co.,LTD	58

View Lastest Price from 1-Methyl-3-nitro-1-nitrosoguanidine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2021-08-31	1-Methyl-3-nitro-1-nitrosoguanidine 70-25-7	US $10.00 / KG	1KG	99.99%	20 tons/month	Wuhan Monad Medicine Tech Co.,LTD
2021-08-12	1-Methyl-3-nitro-1-nitrosoguanidine 70-25-7	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2019-07-06	1-Methyl-3-nitro-1-nitrosoguanidine 70-25-7	US $1.00 / KG	1KG	98%	1kg,5kg,100kg	Career Henan Chemical Co

1-Methyl-3-nitro-1-nitrosoguanidine
70-25-7
US $10.00 / KG
99.99%
Wuhan Monad Medicine Tech Co.,LTD

1-Methyl-3-nitro-1-nitrosoguanidine
70-25-7
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

1-Methyl-3-nitro-1-nitrosoguanidine
70-25-7
US $1.00 / KG
98%
Career Henan Chemical Co

1-Methyl-3-nitro-1-nitrosoguanidine Spectrum

1-Methyl-3-nitro-1-nitrosoguanidine(70-25-7)¹HNMR 1-Methyl-3-nitro-1-nitrosoguanidine(70-25-7)¹³CNMR 1-Methyl-3-nitro-1-nitrosoguanidine(70-25-7)IR1

70-25-7(1-Methyl-3-nitro-1-nitrosoguanidine)Related Search:

METSULFURON METHYL Methylparaben Nitroguanidine Methyl salicylate Methyl acrylate

Tribenuron methyl NITROSOGUANIDINE Methanol Tetramethylguanidine Diazomethane

Basic Violet 1 Kresoxim-methyl 6-Methyl-1,3,5-triazine-2,4-diamine Methyl nitrotoluene

AZINPHOS-METHYL 1-BUTYL-3-NITRO-1-NITROSOGUANIDINE N'-NITRO-N-NITROSO-N-PROPYLGUANIDINE

1of4

1-nitroso-3-nitro-1-methylguanidine Guanidine, 1-methyl-3-nitro-1-nitroso- mnng(n-methyl-n’-nitro-n-nitrosoguanidine n’-nitro-n-nitroso-n-methylguanidine NA 1325 nci-c01423 N-Methyl-N',2-dioxohydrazinecarboximidohydrazide 2-oxide n-methyl-n’-nitro-n-nitroso-guanidin N-Methyl-N-nitrosonitroguanidin n-methylo-n’-nitro-n-nitrozoguanidyny(polish) N-Methyl-N'-nitro-N-nitrosoguanidine (wetted with ca. 50% Water, containing 5g on a dry weight basis) Guanidine, N-methyl-N-nitro-N-nitroso- NMETHYLNNITRONITROSOGUANIDINE 1-METHYL-3-NITRO-NITROSOGUANIDINE METHYL-N-NITRO-N-NITROSOGUANIDINE NITROSOMETHYLNITROGUANIDINE METHYLNITROSONITROGUANIDINE NITROSO-NITRO-METHYLGUANIDINE N-METHYL-N''-NITRO-N-NITROSOGUANIDINE , WETTED WITH 50% WATER Diazomethane precursor, MNNG, N-Methyl-Nμ-nitro-N-nitrosoguanidine 1-Methyl-2-nitro-1-nitrosoguanidine 3-Methyl-1-nitro-3-nitrosoguanidine 1-Methyl-3-nitro-1-nitrosoguanidine (wetted with ca. 50% Water) (unit weight on dry weight basis) 1-METHYL-3-NITRO-1-NITROSOGUANIDINE 1-Methyl-3-nitro-1-nitrosoguanidine (wetted with ca. 50% Water, containing 5g on a dry weight basis) N-METHYL-n,n'-NITROSOGUANIDINE N-Methyl-N'-nitro-N-nitrosoguanidine ,97% N-METHYL-N'-NITRO-N-NITROSOGUANIDINE, MO ISTENED WITH WATER (wetted with ca. 50% Water, containing 5g on a dry weight basis) 1-Methyl-3-nitro-1-nitrosoguanidine 1-Methyl-1-Nitroso-3-nitroguanidine n-metylo-n’-nitro-n-nitrozoguanidyny n-metylo-n’-nitro-n-nitrozoguanidyny(polish) N-Metylo-N'-nitro-N-nitrozoguanidyny N'-Nitro-N-nitroso-N-methylguanidine n-nitroso-n’-nitro-n-methylguanidine N-Nitroso-N-methylnitroguanidine NSC 9369 nsc9369 Rcra waste number U163 rcrawastenumberu163 DIAZOMETHANE PRECURSOR N-METHYL-N-NITROSO-N'-NITROGUANIDINE 1-METHYL-3-NITRO-1-NITROSOGUANIDINE, MOISTENED WITH WATER 1-Methyl-3-nitro-1-nitrosoguanidine (wetted with ca. 50% Water) N-Methyl-N′-nitro-N-nitrosoguanidine (wetted with ca. 50% water) N-Methyl-N'-nitro-N-nitrosoguanidine@100 μg/mL in Toluene 1-Methyl-3-nitro-1-nitrosoguanidine(wettedwithca.50%Water,containing5gonadryweightbasis)> N’-Nitro-N-nitroso-N-methylguanidine (Stabilized with Water) 1-METHYL-3-NITRO-1-NITROSOGUANIDINE (~50% WATER W/W. UNIT WEIGHT ON DRY BASIS) 1-Methyl-3-nitro-1-nitrosouanidine N’-Nitro-N-nitroso-N-methylguanidine (Stabilized with Water) (1.0 mg/mL in Methanol) 1-methyl-3-nitro-1-nitroso-guanidin Methylnitronitrosoguanidine MNG MNNG N-METHYL-N'-NITRO-N-NITROSOGUANIDINE N’-Nitro-N-nitroso-N-methylguanidine (Stabilized with 40% Water)