Crospovidone
- CAS No.
- 25249-54-1
- Chemical Name:
- Crospovidone
- Synonyms
- PVP;PVPP;POP;PVP K-30;POLYVINYLPYRROLIDONE K 90;POLYVINYLPOLYPYRROLIDONE;Polyplasdone;K-30;PLASDONE;POLYVIDONE
- CBNumber:
- CB0744957
- Molecular Formula:
- C6H9NO
- Molecular Weight:
- 111.14176
- MDL Number:
- MFCD00149016
- MOL File:
- 25249-54-1.mol
| Melting point | ~165 °C (dec.)(lit.) |
|---|---|
| form | powder |
| color | White to off-white |
| Water Solubility | Insoluble in water, acid and alkaline. |
| InChI | InChI=1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2 |
| InChIKey | WHNWPMSKXPGLAX-UHFFFAOYSA-N |
| SMILES | N1(C=C)CCCC1=O |
| CAS DataBase Reference | 25249-54-1 |
| FDA 21 CFR | 173.50 |
| EWG's Food Scores | 1 |
| Cosmetics Info | PVP |
SAFETY
Risk and Safety Statements
| Safety Statements | 22-24/25 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| WGK Germany | 1 | |||||||||
| RTECS | TR8370000 | |||||||||
| HS Code | 39059900 | |||||||||
| NFPA 704 |
|
Crospovidone price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 773417 | Poly(vinyl pyrrolidone), cyanomethyl diphenylcarbamodithioate average Mn 6,000, PDI ≤1.2 | 25249-54-1 | 1g | $183 | 2023-01-07 | Buy |
| Alfa Aesar | 041631 | Polyvinylpyrrolidone, cross linked | 25249-54-1 | 100g | $55.1 | 2024-03-01 | Buy |
| Alfa Aesar | 041631 | Polyvinylpyrrolidone, cross linked | 25249-54-1 | 500g | $196 | 2024-03-01 | Buy |
| Chem-Impex | 33085 | Poly(vinylpolypyrrolidone),<=50ìmparticlesize.,meetsUSPspecifications meetsUSPspecifications | 25249-54-1 | 2.5KG | $235.2 | 2021-12-16 | Buy |
| Chem-Impex | 33085 | Poly(vinylpolypyrrolidone),<=50ìmparticlesize.,meetsUSPspecifications meetsUSPspecifications | 25249-54-1 | 5KG | $403.2 | 2021-12-16 | Buy |
Crospovidone Chemical Properties,Uses,Production
Indications and Usage
Polyvinylpyrrolidone (PVP) is a polymer of vinyl pyrrolidone. It is divided based on degree of polymerization into soluble PVP and insoluble polyvinyl polypyrrolidone (PVPP). Commercially available PVPs are divided into four viscosity grades by K value (Fikentscher K): K-15, K-30, K-60, K-90, with respective molecular masses of 10000, 40000, 160000, and 360000. K value or relative molecular mass is one of the important factors determining the various properties of PVP.
Polyvinylpyrrolidone is one of the three major new medicinal materials. It can be used for tablets, granules, a cosolvent for injections, glidant for capsules, liquid preparation and dispersant for colorants, stabilizer for enzymes and thermosensitive drugs, precipitant for poorly soluble drugs, and a removal agent and lubricant for eye drops, etc. The combination of PVP with toxins, drugs, and chemical agents can reduce their toxicity. Complexes with iodine are very stable, with good bactericidal effects, reducing toxicity.
Used in industry as a foaming polystyrene additive, gelling agent, stabilizer, fiber treatment agent, paper processing aid, adhesive, and thickener. Some dyes can also be strongly complexed with PVP, which is the basis for polyvinylpyrrolidone PVP as a dye bleaching agent.
Polyvinylpyrrolidone PVP and its copolymer is an important raw material for cosmetics, mainly used for hair styling agents. The film it forms on hair is flexible and shiny, with good combing performance, without attracting dust. Different resins can satisfy different relative humidity and climatic conditions, so it is an indispensable raw material for styling hair cream, hair gel, and mousse. It can also be used as a cosmetic skin care moisturizing agent, base material of grease, hair coloring dispersant, and foam stabilizer. It can improve the consistency of shampoo. Insoluble PVP is a stabilizer for beer, fruit juice, vinegar, wine and so on, improving its clarity, color and taste.
Toxicity
ADI 0-50(FAO/WHO, 2001)
LD50>100g/kg(rats, orally administered)
LD5012g/kg(rats, abdominal injection)
Can be safely used in food (FDA, §173.55, 2000).
Chemical Properties
white to off-white micro-crystalline powder
Uses
Polyvinylpyrrolidone is used in coatings, printing ink, rubber, glass, leather, cosmetics, soaps, plastics, in paper making and as a stabilizer. It acts as a disintegrant in pharmaceutical tablets and as a fining to extract impurities. It is used to remove polyphenols in beer.
Uses
Polyvinylpyrrolidone (PVP) has been used as a clarifying agent in the food industry.
Uses
PVP (polyvinylpyrrolidone) is a chemical ingredient that, depending on the formulatory requirement, can act as a binder, viscosity controller, emulsion stabilizer, or film former. Its benefits include water and wear resistance, pigment dispersion, a non-greasy feel, and improved stick integrity. PVP is commonly found in waterproof sunscreens, mascaras, and lipsticks in order to improve their wear.
Definition
ChEBI: N-Vinyl-2-pyrrolidone is a member of pyrrolidin-2-ones.
Crospovidone Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Dorra Pharmaceutical Technology Co., Ltd | 025-82232955; | info@dorrapharma.com | China | 34 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10319 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 12272 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8810 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12839 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5857 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | info@fortunachem.com | China | 5978 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5892 | 58 |
| Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-17333973358 | sales06@hbduling.cn | China | 8053 | 58 |
Related articles
- Crospovidone: A Comprehensive Overview
- Crospovidone produced by different preparation methods has different swelling capacity in water and presents various forms.
- Oct 21，2024
View Lastest Price from Crospovidone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-27 | PVPP
25249-54-1
|
US $0.00 / Kg/Drum | 15KG | medicine grade | 10 TONS | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2024-11-27 | Crospovidone
25249-54-1
|
US $6.00 / kg | 1kg | 99% | 2000KG/Month | HebeiShuoshengImportandExportco.,Ltd | |
 |
2024-11-27 | Polyvinylpyrrolidone cross-linked
25249-54-1
|
US $10.00 / kg | 1kg | 99% | 20 ton | Hebei Zhuanglai Chemical Trading Co Ltd |
-
- PVPP
25249-54-1
- US $0.00 / Kg/Drum
- medicine grade
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Crospovidone
25249-54-1
- US $6.00 / kg
- 99%
- HebeiShuoshengImportandExportco.,Ltd
-
- Polyvinylpyrrolidone cross-linked
25249-54-1
- US $10.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co Ltd