TERT-BUTYL ISOCYANIDE
- CAS No.
- 7188-38-7
- Chemical Name:
- TERT-BUTYL ISOCYANIDE
- Synonyms
- 2-ISOCYANO-2-METHYL-PROPANE;TBIN;Propane, 2-isocyano-2-methyl-;T-BUTYLISOCYANIDE;TERT-BUTYL ISONITRILE;2-methylpropyl isocyanide;(CH3)3CNC;TERT-BUTYL ISOCYANIDE;2-methylpropyl cyanide;t-Butylisocyanide,min.98%
- CBNumber:
- CB8121846
- Molecular Formula:
- C5H9N
- Molecular Weight:
- 83.13
- MDL Number:
- MFCD00000002
- MOL File:
- 7188-38-7.mol
- MSDS File:
- SDS
Melting point | 148-150 °C |
---|---|
Boiling point | 91 °C(lit.) |
Density | 0.735 g/mL at 25 °C(lit.) |
refractive index |
n |
Flash point | -2 °C |
storage temp. | Inert atmosphere,2-8°C |
solubility | Soluble in organic solvents such as ethanol, methanol, ether, toluene and dichloromethane. |
form | liquid |
color | colorless |
Specific Gravity | 0.735 |
BRN | 1903156 |
Exposure limits | NIOSH: IDLH 25 mg/m3 |
Stability | store cold |
CAS DataBase Reference | 7188-38-7(CAS DataBase Reference) |
EWG's Food Scores | 1 |
FDA UNII | 22S4Z857K3 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() GHS02,GHS06 |
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---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H225-H330 | |||||||||
Precautionary statements | P210-P304+P340+P310 | |||||||||
Hazard Codes | F,T | |||||||||
Risk Statements | 11-23-2017/11/23 | |||||||||
Safety Statements | 16-45 | |||||||||
RIDADR | UN 1993 3/PG 2 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | EQ7102500 | |||||||||
HazardClass | 3 | |||||||||
PackingGroup | II | |||||||||
HS Code | 29299090 | |||||||||
NFPA 704 |
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TERT-BUTYL ISOCYANIDE price More Price(23)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 260630 | tert-Butyl isocyanide 98% | 7188-38-7 | 1g | $56.6 | 2024-03-01 | Buy |
Sigma-Aldrich | 260630 | tert-Butyl isocyanide 98% | 7188-38-7 | 5g | $173 | 2024-03-01 | Buy |
TCI Chemical | B1274 | tert-Butyl Isocyanide >95.0%(GC) | 7188-38-7 | 5mL | $138 | 2024-03-01 | Buy |
TCI Chemical | B1274 | tert-Butyl Isocyanide >95.0%(GC) | 7188-38-7 | 25mL | $476 | 2024-03-01 | Buy |
Alfa Aesar | L19747 | tert-Butyl isocyanide 98% | 7188-38-7 | 1g | $52.1 | 2024-03-01 | Buy |
TERT-BUTYL ISOCYANIDE Chemical Properties,Uses,Production
Chemical Properties
clear colorless liquid
Uses
tert-Butyl isocyanide is used in a tin-free procedure for alkyl radical reactions in the presence of a free-radical initiator. It is a useful intermediate in multicomponent reactions. It is also used in the synthesis of coumarines, 4H-chromenes, isoxazolines and to trap 2-cyclopropylidene-1,3-diones.
Preparation
Phosgene (1.0 kg, 10.1 mol) was delivered through a wide tube into a stirred solution of N-t-butylformamide (1.01 kg, 10.0 mol) in triethylamine (1.30 kg) and o-dichlorobenzene (7.0 L) in a flask fitted with a reflux condenser charged with a freezing mixture of ice and salt (-20 C°). Water was added, the layers were separated, and the non-aqueous layer was dried over anhydrous potassium carbonate or magnesium sulfate and fractionated; bp 90–92 C°/750 mmHg; yield: 681 g (82%).
Preparation
CAUTION: Use a well-ventilated hood and observe all precautions when using hydrogen cyanide.
To a 1-1, stainless steel Hoke pressure cylinder in a well-ventilated hood is added 196 gm (3.5 moles) of isobutene, 95 gm (3.5 moles) of hydrogen cyanide, and 100 gm (0.7 mole) or cuprous bromide. The cylinder is closed, shaken for 15 hr at 70°C, cooled to room temperature, and vented cautiously in the hood, and the viscous residue is poured slowly into aqueous potassium cyanide (260 gm in 100 ml of water) to decompose the cuprous complex, liberating an organic layer. The organic layer is separated, dried, and distilled under reduced pressure to afford 97 gm, b.p. 60-63°C (314 mm Hg), ng 1.3749, IR 2143 s, 1472 m, 1368 m, 1230 m, 1208 m, 855 w c m - 1; yield, 33% based on starting isobutylene; 16% based on CuBr.
General Description
Carbon dative bond formation by tert-butyl isocyanide on the germanium (100) surface has been reported. It also forms complexes with metals and inserts into metal-carbon bonds to form iminoacyls.
TERT-BUTYL ISOCYANIDE Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20294 | 58 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 16914 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21668 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29894 | 58 |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 7621 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
Nanjing jinheyou Trading Co., Ltd. | 15705188088 | admin@jheyou.com | CHINA | 1268 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
View Lastest Price from TERT-BUTYL ISOCYANIDE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-03-29 | TERT-BUTYL ISOCYANIDE
7188-38-7
|
US $6.00-0.20 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
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2022-09-12 | TERT-BUTYL ISOCYANIDE
7188-38-7
|
US $0.00-0.00 / KG | 1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd. | |
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2021-07-13 | TERT-BUTYL ISOCYANIDE
7188-38-7
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- TERT-BUTYL ISOCYANIDE
7188-38-7
- US $6.00-0.20 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-
- TERT-BUTYL ISOCYANIDE
7188-38-7
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- TERT-BUTYL ISOCYANIDE
7188-38-7
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd