Isothiazolinones
- CAS No.
- 26172-55-4
- Chemical Name:
- Isothiazolinones
- Synonyms
- CMIT;Isothiazolinone;CMI;CMIT/MIT;5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE;MCI;5-Chloro-2-methyl-3(2H)-isothiazolone;Chloromethylisothiazolinone;5-chloro-2-methyl-2H-isothiazol-3-one;isothiazolin
- CBNumber:
- CB4132565
- Molecular Formula:
- C4H4ClNOS
- Molecular Weight:
- 149.6
- MDL Number:
- MFCD00792550
- MOL File:
- 26172-55-4.mol
- MSDS File:
- SDS
Melting point | 42-45?C |
---|---|
Boiling point | 109.7°C |
Density | 1.25 (14% aq.) |
refractive index |
n |
storage temp. | Refrigerator |
solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated) |
form | Liquid |
pka | -4.06±0.40(Predicted) |
Stability | Stable. Incompatible with strong oxidizing agents. |
LogP | 0.240 (est) |
Indirect Additives used in Food Contact Substances | 5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE |
CAS DataBase Reference | 26172-55-4(CAS DataBase Reference) |
FDA UNII | DEL7T5QRPN |
NIST Chemistry Reference | 5-Chloro-2-methyl-3(2h)-isothiazolone(26172-55-4) |
EPA Substance Registry System | 5-Chloro-2-methyl-4-isothiazolin-3-one (26172-55-4) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H317-H319-H412 |
Precautionary statements | P261-P264-P273-P280-P302+P352-P305+P351+P338 |
Hazard Codes | C,N,T,Xn |
Risk Statements | 34-43-50-20/21/22-50/53-23/24/25-42/43 |
Safety Statements | 26-36/37/39-45-60-61-24-28-36/37-23 |
RIDADR | UN 1760 8/PG 2 |
WGK Germany | 1 |
RTECS | NX8156850 |
HazardClass | 8 |
PackingGroup | III |
HS Code | 3808929090 |
Isothiazolinones price More Price(32)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | PHR1597 | CMIT/MIT Pharmaceutical Secondary Standard; Certified Reference Material | 26172-55-4 | 1ml | $97.5 | 2024-03-01 | Buy |
TRC | C369235 | 5-Chloro-2-methyl-3-isothiazolone | 26172-55-4 | 2.5mg | $160 | 2021-12-16 | Buy |
Usbiological | C5029-26 | 5-Chloro-2- | 26172-55-4 | 2.5mg | $496 | 2021-12-16 | Buy |
Usbiological | 435989 | 5-Chloro-2- | 26172-55-4 | 1mg | $360 | 2021-12-16 | Buy |
Usbiological | 161851 | 5-Chloro-2- | 26172-55-4 | 1g | $418 | 2021-12-16 | Buy |
Isothiazolinones Chemical Properties,Uses,Production
Description
Isothiazolinone is a heterocyclic chemical compound related to isothiazole. Isothiazolinone is an antimicrobial preservative that is often used to control fungi, bacteria, and algae. Since water-containing solutions are the breeding grounds for bacteria, isothiazolinone can easily be used in such solutions.
Applications
Although isothiazolinones have no direct applications, their derivatives such as 5-chloro-2-methyl-4-isothiazolin-3-on and 2-methyl-4-isothiazolin-3 which are used together as preservatives in commercial households and cosmetics products, for instance, cleaners, shampoos, and washing materials. Notably, various products that use isothiazolinones are in the market, including shampoo, hand sanitizer, and lotions. Isothiazolinones is used in these products as an inhibitor of microbial activity that could lead to the product spoiling before the expected expiration date.
Safety Information
The recommended use of isothiazolinone products by the manufacturers used as wrinkle releaser is not harmful. However, allergy to skin is one of the most reported issue with isothiazolinone.
Description
Methy1chloro-isothiazolinone (MCI) is contained, along with methylisothiazolinone (MI), in Kathon cosmetic grade (CG) and MCI/MI. It is irritant and sensitizer.
Chemical Properties
Liquid
Uses
A isothiazolidin-3-one derivative as antimicrobial. It was tested for inhibition of PCAF activity. 5-Chloroisothiazolinones showed the most potent inhibition of PCAF.
Uses
Isocil(R) RW is a high performance industrial microbiocide for use in recirculating water cooling towers, wood, mold and mildew control, pulp and paper mills, air washer systems. Suggested applications: Industrial water treatment. Very low use levels.
Uses
Isocil(R) PC is a cost-effective antimicrobial for personal care formulations. Suggested applications: personal care preservative.
Uses
Isocil(R) MW-14 is a high performance biocide for preserving metal working fluids, hydraulic fluids, polymer emulsions, pigment dispersions. Suggested applications: preservative concentrate. Very low level.
Definition
ChEBI: A 1,2-thiazole that is 4-isothiazolin-3-one bearing a methyl group on the nitrogen atom and a chlorine at C-5. It is a powerful biocide and preservative and is the major active ingredient in the commercial product KathonTM.
Isothiazolinones Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34571 | 58 |
Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | info@fortunachem.com | China | 5989 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5867 | 58 |
Suzhou Genemill Biotechnology Co.,Ltd | +8615862502491 | aimeegao@genemill.com | China | 39 | 58 |
Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | lisa@kingfinertech.com | China | 2989 | 58 |
Wuhan Quanjinci New Material Co.,Ltd. | +8615271838296 | kyra@quanjinci.com | China | 1534 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20294 | 58 |
Shandong Juchuang Chemical Co., LTD | +undefined15030412209 | admin@juchuangchem.com | China | 387 | 58 |
Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3002 | 58 |
Hebei Shengyang Water Conservancy Engineering Co., Ltd. | +8615373025980 | clara@hbshengyang.com | China | 873 | 58 |
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View Lastest Price from Isothiazolinones manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2024-09-05 | Isothiazolinones
26172-55-4
|
US $5.60-3.20 / kg | 1kg | 99% | 10 tons | Shandong Deshang Chemical Co., Ltd. | |
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2024-09-05 | Isothiazolinones
26172-55-4
|
US $100.00-75.00 / ton | 1ton | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | |
![]() |
2024-09-04 | Isothiazolinones
26172-55-4
|
US $0.00-0.00 / kg | 1kg | 98%min | 10MT | WUHAN FORTUNA CHEMICAL CO., LTD |
-
- Isothiazolinones
26172-55-4
- US $5.60-3.20 / kg
- 99%
- Shandong Deshang Chemical Co., Ltd.
-
- Isothiazolinones
26172-55-4
- US $100.00-75.00 / ton
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
-
- Isothiazolinones
26172-55-4
- US $0.00-0.00 / kg
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD