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BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE

CAS No.
184951-87-9
Chemical Name:
BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE
Synonyms
BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE;(S)-2-(Boc-amino)-3-phenyl propanethioic O-acid-1-;(S)-2-(BOC-AMINO)-PRPPNETHIOIC O-ACID-1-(6-NITRO)BENZOTRIAZOLIDE;BOC-L-2-AMINO-3-PHENYLPROPANETHIOIC ACID-1-(6-NITRO)BENZOTRIAZOLIDE;(S)-2-(BOC-AMINO)-3-PHENYL-PROPANETHIOIC O-ACID-1-(6-NITRO)BENZOTRIAZOLIDE;(S)-2-[(t-Butoxycarbonyl)amino]-1-(6-nitrobenzotriazol-1-yl)-3-phenylpropane-1-thione;N-ALPHA-T-BUTOXYCARBONYL-L-2-AMINO-3-PHENYLPROPANETHIOIC ACID-1-(6-NITRO) BENZOTRIAZOLIDE;tert-butyl N-[(2S)-1-(6-nitrobenzotriazol-1-yl)-3-phenyl-1-sulfanylidenepropan-2-yl]carbamate;[(1S)-2-(6-Nitro-1H-benzotriazol-1-yl)-1-(phenylmethyl)-2-thioxoethyl]carbamic acid tert-butyl ester;Carbamic acid, [(1S)-2-(6-nitro-1H-benzotriazol-1-yl)-1-(phenylmethyl)-2-thioxoethyl]-, 1,1-dimethylethyl ester (9CI)
CBNumber:
CB0753852
Molecular Formula:
C20H21N5O4S
Molecular Weight:
427.48
MDL Number:
MFCD01318725
MOL File:
184951-87-9.mol
MSDS File:
SDS
Last updated:2023-04-27 16:27:43

BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE Properties

Density 1.36
storage temp. -15°C
pka 10.06±0.46(Predicted)

BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth Carbosynth FB111268 Boc-Thionophe-1-(6-nitro)benzotriazolide 184951-87-9 250mg $150 2021-12-16 Buy
Biosynth Carbosynth FB111268 Boc-Thionophe-1-(6-nitro)benzotriazolide 184951-87-9 500mg $260 2021-12-16 Buy
Biosynth Carbosynth FB111268 Boc-Thionophe-1-(6-nitro)benzotriazolide 184951-87-9 1g $453 2021-12-16 Buy
American Custom Chemicals Corporation CCH0007944 (S)-2-(BOC-AMINO)-3-PHENYL PROPANETHIOIC O-ACID-1-(6-NITRO)BENZOTRIAZOLIDE 95.00% 184951-87-9 5MG $497.43 2021-12-16 Buy
AK Scientific 0001CS Boc-ThionoPhe-1-(6-nitro)benzotriazolide 184951-87-9 1g $661 2021-12-16 Buy
Product number Packaging Price Buy
FB111268 250mg $150 Buy
FB111268 500mg $260 Buy
FB111268 1g $453 Buy
CCH0007944 5MG $497.43 Buy
0001CS 1g $661 Buy

BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE Chemical Properties,Uses,Production

Uses

BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Synthesis

1.jpg
To a solution of thioanilide 7 (2 mmol) dissolved by gentle warming at 40 °C and then cooled to 0 °C in glacial acetic acid (diluted with 5% water, 15 mL) was added NaNO2 (0.21 g, 3 mmol) in portions over 5 min with stirring. After 30 min, ice water (~100 mL) was added, and the precipitated product was filtered and washed with water. The orange solid was dried in vacuo at rt overnight and then at 50 °C for 4 h to afford benzotriazoles 1-(N-BOC-L-thionophenylalaninyl)-6-nitrobenzotriazole (9b): yield 81%. as amorphous solids of sufficient purity for use in the next step.

13734-34-4
184951-87-9
Synthesis of BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE from N-(tert-Butoxycarbonyl)-L-phenylalanine

BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE Preparation Products And Raw materials

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TCI (Shanghai) Chemical Trading Co., Ltd. 021-021-61109150 sales@tcisct.com China 31121 58
Carbosynth -- sales@carbosynth.com United Kingdom 6005 58
(S)-2-(BOC-AMINO)-3-PHENYL-PROPANETHIOIC O-ACID-1-(6-NITRO)BENZOTRIAZOLIDE (S)-2-(BOC-AMINO)-PRPPNETHIOIC O-ACID-1-(6-NITRO)BENZOTRIAZOLIDE N-ALPHA-T-BUTOXYCARBONYL-L-2-AMINO-3-PHENYLPROPANETHIOIC ACID-1-(6-NITRO) BENZOTRIAZOLIDE (S)-2-(Boc-amino)-3-phenyl propanethioic O-acid-1- BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE BOC-L-2-AMINO-3-PHENYLPROPANETHIOIC ACID-1-(6-NITRO)BENZOTRIAZOLIDE [(1S)-2-(6-Nitro-1H-benzotriazol-1-yl)-1-(phenylmethyl)-2-thioxoethyl]carbamic acid tert-butyl ester Carbamic acid, [(1S)-2-(6-nitro-1H-benzotriazol-1-yl)-1-(phenylmethyl)-2-thioxoethyl]-, 1,1-dimethylethyl ester (9CI) (S)-2-[(t-Butoxycarbonyl)amino]-1-(6-nitrobenzotriazol-1-yl)-3-phenylpropane-1-thione tert-butyl N-[(2S)-1-(6-nitrobenzotriazol-1-yl)-3-phenyl-1-sulfanylidenepropan-2-yl]carbamate 184951-87-9 C20H21N5O4S