ChemicalBook >> CAS DataBase List >>N-BUTANOYL-D-ERYTHRO-SPHINGOSINE
N-BUTANOYL-D-ERYTHRO-SPHINGOSINE
- CAS No.
- 74713-58-9
- Chemical Name:
- N-BUTANOYL-D-ERYTHRO-SPHINGOSINE
- Synonyms
- CERAMIDE C4;N-Butyryl-D-sphingosine;C4 Ceramide (d18:1/4:0);N-BUTANOYL-D-ERYTHRO-SPHINGOSINE;N-Butanoyl-D-erythro-sphingosineCeramide C4;N-Butanoyl-D-erythro-sphingosine, synthetical;(2S,3R,4E)-2-(Butyrylamino)-4-octadecene-1,3-diol;N-Butanoyl-D-erythro-sphingosine, synthetical, 99+%;N-BUTANOYL-D-ERYTHRO-SPHINGOSINE, 99+%, SYNTHETICAL;N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)butyramide
- CBNumber:
- CB0757643
- Molecular Formula:
- C22H43NO3
- Molecular Weight:
- 369.58
- MDL Number:
- MFCD02181206
- MOL File:
- 74713-58-9.mol
Last updated:2025-01-27 09:38:02
| Melting point | 64-67°C |
|---|---|
| Boiling point | 499.67°C (rough estimate) |
| Density | 1.0181 (rough estimate) |
| refractive index | 1.5614 (estimate) |
| storage temp. | -20°C |
| solubility | DMF: 20 mg/mL; DMSO: 20 mg/mL; Ethanol: 30 mg/mL; PBS (pH 7.2): < 50 μg/ml |
| form | A crystalline solid |
| pka | 13.54±0.20(Predicted) |
| CAS DataBase Reference | 74713-58-9 |
| FDA UNII | SF3LP91341 |
| UNSPSC Code | 12352211 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Safety Statements | 24/25 |
|---|---|
| WGK Germany | 3 |
| HS Code | 29225000 |
N-BUTANOYL-D-ERYTHRO-SPHINGOSINE price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 56857 | N-Butyryl-D-sphingosine ≥98.0% (TLC) | 74713-58-9 | 250mg | $726 | 2023-06-20 | Buy |
| Cayman Chemical | 22528 | C4 Ceramide (d18:1/4:0) | 74713-58-9 | 10mg | $63 | 2024-03-01 | Buy |
| Cayman Chemical | 22528 | C4 Ceramide (d18:1/4:0) | 74713-58-9 | 250mg | $533 | 2024-03-01 | Buy |
| Cayman Chemical | 22528 | C4 Ceramide (d18:1/4:0) | 74713-58-9 | 50mg | $153 | 2024-03-01 | Buy |
| Cayman Chemical | 22528 | C4 Ceramide (d18:1/4:0) | 74713-58-9 | 100mg | $275 | 2024-03-01 | Buy |
N-BUTANOYL-D-ERYTHRO-SPHINGOSINE Chemical Properties,Uses,Production
Chemical Properties
Off-white solid
Uses
N-butyroyl-D-erythro-sphingosine is a ceramide derivative for pharmaceutical use as antitumor agents.
Biological Activity
C4 Ceramide (d18:1/4:0) is implicated in a series of mutual autophosphorylation and phosphorylation actions between 3-phosphoinositide-dependent kinase 1 (PDK1) and serum/glucocorticoid-induced protein kinase 1 (SGK1). It stimulates cyclic adenosine monophosphate (cAMP)-activated chloride secretion and represses hypersecretion of interleukin-8 (IL-8). C4 Ceramide might be a potential therapeutic for cystic fibrosis (CF).
N-BUTANOYL-D-ERYTHRO-SPHINGOSINE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 36)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alfa Chemistry | Info@alfa-chemistry.com | United States | 24072 | 58 | |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 021-61259108 18621169109 | market03@meryer.com | China | 40228 | 62 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32321 | 50 |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17770 | 75 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 1316706386 | anhua.mao@aladdin-e.com | China | 25003 | 65 |
| Yichang Zhongyitai Trading Co., Ltd. | 0717-6449896 13886658719 | root@zhongyitai.com | China | 1977 | 58 |
| Alfa Chemistry | 1-516-6625404 | support@alfa-chemistry.com | United States | 9171 | 60 |
| Codow Chemical Co.,Ltd. | 18620099427 | amy@howeipharm.com | China | 17687 | 55 |
74713-58-9(N-BUTANOYL-D-ERYTHRO-SPHINGOSINE)Related Search:
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N-BUTANOYL-D-ERYTHRO-SPHINGOSINE
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74713-58-9
Mixed Fatty Acids
Activators
Fatty Acid Derivatives & Lipids
Glycerols
Inhibitors
Protein Kinase Inhibitors and Activators