1,4-DIBROMOISOQUINOLINE
- CAS No.
- 51206-40-7
- Chemical Name:
- 1,4-DIBROMOISOQUINOLINE
- Synonyms
- 1,4-DIBROMOISOQUINOLINE;Isoquinoline, 1,4-dibromo-;1,4-DIBROMOISOQUINOLINE ISO 9001：2015 REACH
- CBNumber:
- CB0769271
- Molecular Formula:
- C9H5Br2N
- Molecular Weight:
- 286.95
- MDL Number:
- MFCD00234475
- MOL File:
- 51206-40-7.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
1,4-DIBROMOISOQUINOLINE price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | D425538 | 1,4-Dibromoisoquinoline | 51206-40-7 | 500mg | $175 | 2021-12-16 | Buy |
| Matrix Scientific | 072377 | 1,4-Dibromoisoquinoline 95+% | 51206-40-7 | 250mg | $537 | 2021-12-16 | Buy |
| AK Scientific | W6621 | 1,4-Dibromoisoquinoline | 51206-40-7 | 10g | $1011 | 2021-12-16 | Buy |
| Matrix Scientific | 072377 | 1,4-Dibromoisoquinoline 95+% | 51206-40-7 | 1g | $1158 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0069282 | 1,4-DIBROMO-ISOQUINOLINE 96.00% | 51206-40-7 | 250MG | $1167.71 | 2021-12-16 | Buy |
1,4-DIBROMOISOQUINOLINE Chemical Properties,Uses,Production
Synthesis
491-30-5
51206-40-7
General procedure for the synthesis of 1,4-dibromoisoquinoline from 1-hydroxyisoquinoline: 2.90 g (19.07 mmol) of 1-hydroxyisoquinoline was mixed with 14.40 g (33.68 mmol) of phosphorus pentabromide and heated to a molten state at 140 °C. The reaction was carried out at a temperature of about 2.5 ° C. The reaction was carried out in the presence of a red liquid. During the reaction, the melt gradually transformed into a red liquid and after about 10 minutes, the reaction mixture solidified and subsequently cooled to room temperature. The solidified reaction mixture was pulverized and slowly poured into ice water. The resulting solid product was collected by filtration and dried in air. 5.50 g of 1,4-dibromoisoquinoline was finally obtained in 96% yield with a melting point of 94-96 °C. The product had an Rf value of 0.66 in a hexane solution of 40% ethyl acetate.
References
[1] Patent: EP1228063, 2009, B1. Location in patent: Page/Page column 32
[2] Patent: WO2007/118602, 2007, A1. Location in patent: Page/Page column 51
[3] Journal of Medicinal Chemistry, 2018, vol. 61, # 17, p. 8029 - 8047
[4] Patent: WO2017/103586, 2017, A1. Location in patent: Page/Page column 38
[5] Patent: US2010/222345, 2010, A1. Location in patent: Page/Page column 97
1,4-DIBROMOISOQUINOLINE Preparation Products And Raw materials
1,4-DIBROMOISOQUINOLINE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49733 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30230 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 22418 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53900 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
View Lastest Price from 1,4-DIBROMOISOQUINOLINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-03-24 | 1,4-DIBROMOISOQUINOLINE
51206-40-7
|
US $1.10 / g | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited |
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- 1,4-DIBROMOISOQUINOLINE
51206-40-7
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited