ACA
- CAS No.
- 99196-74-4
- Chemical Name:
- ACA
- Synonyms
- ACL;ACA;AMARANTHUS CAUDATUS LECTIN;GAMRBCZMOOMBSQ-CCEZHUSRSA-N;N-(4-Pentylcinnamoyl)anthranilic acid;N-(p-Amylcinnamoyl)anthranilic acid >=98% (HPLC);2-[3-(4-pentylphenyl)prop-2-enoylamino]benzoic acid;2-[[1-oxo-3-(4-Pentylphenyl)-2-propen-1-yl]amino]-benzoic acid;Benzoic acid, 2-[[(2E)-1-oxo-3-(4-pentylphenyl)-2-propen-1-yl]amino]-
- CBNumber:
- CB0782117
- Molecular Formula:
- C21H23NO3
- Molecular Weight:
- 337.41
- MDL Number:
- MFCD01321668
- MOL File:
- 99196-74-4.mol
Boiling point | 563.1±50.0 °C(Predicted) |
---|---|
Density | 1.178±0.06 g/cm3(Predicted) |
storage temp. | room temp |
solubility | DMSO: ≥20mg/mL |
form | powder |
pka | 3.46±0.36(Predicted) |
color | white to off-white |
FDA UNII | LCJ9M6AJ5F |
ACA price More Price(3)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | A8486 | N-(p-Amylcinnamoyl)anthranilic acid ≥98% (HPLC) | 99196-74-4 | 5mg | $84.1 | 2024-03-01 | Buy |
Sigma-Aldrich | A8486 | N-(p-Amylcinnamoyl)anthranilic acid ≥98% (HPLC) | 99196-74-4 | 25mg | $335 | 2024-03-01 | Buy |
American Custom Chemicals Corporation | PRO0004861 | ACA 95.00% | 99196-74-4 | 5MG | $495.56 | 2021-12-16 | Buy |
ACA Chemical Properties,Uses,Production
Uses
N-(p-Amylcinnamoyl)anthranilic acid has been used as a transient receptor potential cation channel subfamily M member 2 (TRPM2) inhibitor, in studying its role in regulating the production of reactive oxygen species (ROS).
Definition
ChEBI: N-(p-amylcinnamoyl)anthranilic acid is an amidobenzoic acid that is anthranilic acid in which one of the anilino hydrogens is replaced by a 4-pentylcinnamoyl group. It is a transient receptor potential (TRP) channel blocker and phospholipase A2 (PLA2) inhibitor. It has a role as an EC 3.1.1.4 (phospholipase A2) inhibitor and a TRP channel blocker. It is an amidobenzoic acid, a member of cinnamamides and a secondary carboxamide.
General Description
N-(p-Amylcinnamoyl)anthranilic acid (ACA) functions as a broad spectrum phospholipase A2 inhibitor and blocks transient receptor potential (TRP) channels. It inhibits calcium activated chloride current in cardiac ventricular myocytes. ACA regulates various ion channels.
Biochem/physiol Actions
Broad spectrum phospholipase A2 (PLA2) inhibitor and TRP channel blocker.
ACA Preparation Products And Raw materials
Raw materials
Preparation Products
ACA Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51456 | 80 |
Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44918 | 58 |
Shanghai Yaji Biological Technology Co., Ltd. | 021-34661275 15301693058 | yajikit@163.com | China | 9719 | 58 |
Supplier | Advantage |
---|---|
Sigma-Aldrich | 80 |
Energy Chemical | 58 |
Shanghai Yaji Biological Technology Co., Ltd. | 58 |