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ChemicalBook >> CAS DataBase List >>Acetamide, 2-[[3,4-dihydro-6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]-N-[(tetrahydro-2-furanyl)methyl]-

Acetamide, 2-[[3,4-dihydro-6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]-N-[(tetrahydro-2-furanyl)methyl]-

Acetamide, 2-[[3,4-dihydro-6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]-N-[(tetrahydro-2-furanyl)methyl]- Structure
Acetamide, 2-[[3,4-dihydro-6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]-N-[(tetrahydro-2-furanyl)methyl]- structure
CAS No.
896683-84-4
Chemical Name:
Acetamide, 2-[[3,4-dihydro-6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]-N-[(tetrahydro-2-furanyl)methyl]-
Synonyms
IL-1β,Inhibitor,STAM-binding protein,inhibit,BC-1471,BC1471,DUBs,STAMBP,NALP7,BC 1471,Deubiquitinase;Acetamide, 2-[[3,4-dihydro-6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]-N-[(tetrahydro-2-furanyl)methyl]-
CBNumber:
CB08110204
Molecular Formula:
C27H32N4O4S
Molecular Weight:
508.63
MDL Number:
MOL File:
896683-84-4.mol
Last updated:2024-07-02 08:54:58
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Acetamide, 2-[[3,4-dihydro-6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]-N-[(tetrahydro-2-furanyl)methyl]- Properties

storage temp. Store at -20°C
solubility DMSO : 50 mg/mL (98.30 mM; Need ultrasonic)
form Solid
color White to off-white

Acetamide, 2-[[3,4-dihydro-6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]-N-[(tetrahydro-2-furanyl)methyl]- Chemical Properties,Uses,Production

Definition

ChEBI: 2-[[6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]-N-(2-oxolanylmethyl)acetamide is a member of quinazolines.

Biological Activity

BC-1471 is a STAM-binding protein (STAMBP) deubiquitinase inhibitor. BC-1471 inhibits NALP7 (NACHT, LRR and PYD domains-containing protein 7) inflammasome activity[1].

References

[1]. Bednash JS, et al. Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity. Nat Commun. 2017 May 11;8:15203.

Acetamide, 2-[[3,4-dihydro-6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]-N-[(tetrahydro-2-furanyl)methyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

Acetamide, 2-[[3,4-dihydro-6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]-N-[(tetrahydro-2-furanyl)methyl]- Suppliers

Global( 9)Suppliers
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Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581 sales@chemhifuture.com China 3136 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 15317229551 15151849396@163.com China 996 58
Nantong Hi-Future Biotechnology Co., Ltd 18051384581 sales@chemhifuture.com China 3057 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24647 58
Shanghai Tachizaki Biomedical Research Center 18014399201 sales@chemlab-tachizaki.com China 2551 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11975 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 021-59167510 18117107507 vip@med-life.cn China 4997 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9268 58
Supplier Advantage
Nantong HI-FUTURE Biology Co., Ltd. 		58
Aladdin Scientific 		58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 58
Nantong Hi-Future Biotechnology Co., Ltd 58
TargetMol Chemicals Inc. 58
Shanghai Tachizaki Biomedical Research Center 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 58
RD International Technology Co., Limited 58

Acetamide, 2-[[3,4-dihydro-6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]-N-[(tetrahydro-2-furanyl)methyl]- Spectrum

Acetamide, 2-[[3,4-dihydro-6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]-N-[(tetrahydro-2-furanyl)methyl]-(896683-84-4)1HNMR
Acetamide, 2-[[3,4-dihydro-6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]-N-[(tetrahydro-2-furanyl)methyl]- IL-1β,Inhibitor,STAM-binding protein,inhibit,BC-1471,BC1471,DUBs,STAMBP,NALP7,BC 1471,Deubiquitinase 896683-84-4